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M

Maria Virginia Soldovieri

University of Molise
H指数:33
被引数:3,443

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Constitutive opening of the Kv7.2 pore activation gate causes KCNQ2- developmental encephalopathy

Kv7.2孔激活门的结构性打开导致KCNQ2-发育性脑病

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-11-270
PRE
Nappi, Mario; Alberini, Giulio; Berselli, Alessandro; Roscioni, Agnese; Soldovieri, Maria Virginia; Servettini, Ilenio; Barrese, Vincenzo; Weckhuysen, Sarah; Chiu, Ting-Gee Annie; Scheffer, Ingrid E.; Benfenati, Fabio; Maragliano, Luca; Miceli, Francesco; Taglialatela, Maurizio
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-05-235
OAAI
Iraci, Nunzio; Carotenuto, Lidia; Ciaglia, Tania; Belperio, Giorgio; Di Matteo, Francesca; Mosca, Ilaria; Carleo, Giusy; Basilicata, Manuela Giovanna; Ambrosino, Paolo; Turcio, Rita; Puzo, Deborah; Pepe, Giacomo; Gomez-Monterrey, Isabel; Soldovieri, Maria Virginia; Di Sarno, Veronica; Campiglia, Pietro; Miceli, Francesco; Bertamino, Alessia; Ostacolo, Carmine; Taglialatela, Maurizio
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: Precision medicine approach with fluoxetine

一种引起发育性和癫痫性脑病的新型KCNC1功能获得变体: 氟西汀的精准医学方法

EPILEPSIA
IF6.6
2023-06-0211
PRE
Ambrosino, Paolo; Ragona, Francesca; Mosca, Ilaria; Vannicola, Chiara; Canafoglia, Laura; Solazzi, Roberta; Rivolta, Ilaria; Freri, Elena; Granata, Tiziana; Messina, Giuliana; Castellotti, Barbara; Gellera, Cinzia; Soldovieri, Maria Virginia; DiFrancesco, Jacopo Cosimo; Taglialatela, Maurizio
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism
EBIOMEDICINE
IF10.8
2022-07-0121
OAAI
Miceli, Francesco; Millevert, Charissa; Soldovieri, Maria Virginia; Mosca, Ilaria; Ambrosino, Paolo; Carotenuto, Lidia; Schrader, Dewi; Lee, Hyun Kyung; Riviello, James; Hong, William; Risen, Sarah; Emrick, Lisa; Amin, Hitha; Ville, Dorothee; Edery, Patrick; de Bellescize, Julitta; Michaud, Vincent; Van-Gils, Julien; Goizet, Cyril; Willemsen, Marjolein H.; Kleefstra, Tjitske; Moller, Rikke S.; Bayat, Allan; Devinsky, Orrin; Sands, Tristan; Korenke, G. Christoph; Kluger, Gerhard; Mefford, Heather C.; Brilstra, Eva; Lesca, Gaetan; Milh, Mathieu; Cooper, Edward C.; Taglialatela, Maurizio; Weckhuysen, Sarah
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-04-0418
OA
Nappi, Mario; Barrese, Vincenzo; Carotenuto, Lidia; Lesca, Gaetan; Labalme, Audrey; Ville, Dorothee; Smol, Thomas; Rama, Melanie; Dieux-Coeslier, Anne; Rivier-Ringenbach, Clotilde; Soldovieri, Maria Virginia; Ambrosino, Paolo; Mosca, Ilaria; Pusch, Michael; Miceli, Francesco; Taglialatela, Maurizio
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors

钙细胞毒性使前列腺癌细胞对局部晚期肿瘤的标准治疗敏感

CELL DEATH & DISEASE
IF9.6
2020-12-0720
OAAI
Alaimo, Alessandro; Lorenzoni, Marco; Ambrosino, Paolo; Bertossi, Arianna; Bisio, Alessandra; Macchia, Alice; Zoni, Eugenio; Genovesi, Sacha; Cambuli, Francesco; Foletto, Veronica; De Felice, Dario; Soldovieri, Maria Virginia; Mosca, Ilaria; Gandolfi, Francesco; Brunelli, Matteo; Petris, Gianluca; Cereseto, Anna; Villarroel, Alvaro; Thalmann, George; Carbone, Francesco Giuseppe; Kruithof-de Julio, Marianna; Barbareschi, Mattia; Romanel, Alessandro; Taglialatela, Maurizio; Lunardi, Andrea
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy

加巴喷丁治疗KCNQ2发展性癫痫脑病患者

PHARMACOLOGICAL RESEARCH
IF10.5
2020-10-0110
OAAI
Soldovieri, Maria Virginia; Freri, Elena; Ambrosino, Paolo; Rivolta, Ilaria; Mosca, Ilaria; Binda, Anna; Murano, Carmen; Ragona, Francesca; Canafoglia, Laura; Vannicola, Chiara; Solazzi, Roberta; Granata, Tiziana; Castellotti, Barbara; Messina, Giuliana; Gellera, Cinzia; Labalme, Audrey; Lesca, Gaetan; DiFrancesco, Jacopo C.; Taglialatela, Maurizio
A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate

良性新生儿癫痫家族中电压感应S4段的新型Kv7.3变体: β-羟基丁酸酯的功能表征和体外拯救

FRONTIERS IN PHYSIOLOGY
IF3.4
2020-09-047
OAAI
Miceli, Francesco; Carotenuto, Lidia; Barrese, Vincenzo; Soldovieri, Maria Virginia; Heinzen, Erin L.; Mandel, Arthur M.; Lippa, Natalie; Bier, Louise; Goldstein, David B.; Cooper, Edward C.; Cilio, Maria Roberta; Taglialatela, Maurizio; Sands, Tristan T.
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators

构象限制的瑞替加滨类似物作为新型神经元Kv7通道激活剂的合成和药理学表征

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-12-0927
OAAI
Ostacolo, Carmine; Miceli, Francesco; Di Sarno, Veronica; Nappi, Piera; Iraci, Nunzio; Soldovieri, Maria Virginia; Ciaglia, Tania; Ambrosino, Paolo; Vestuto, Vincenzo; Lauritano, Anna; Musella, Simona; Pepe, Giacomo; Basilicata, Manuela Giovanna; Manfra, Michele; Perinelli, Diego Romano; Novellino, Ettore; Bertamino, Alessia; Gomez-Monterrey, Isabel M.; Campiglia, Pietro; Taglialatela, Maurizio
Autism and developmental disability caused by KCNQ3 gain-of-function variants

KCNQ3功能获得变异引起的自闭症和发育障碍

ANNALS OF NEUROLOGY
IF7.7
2019-06-2681
OAAI
Sands, Tristan T.; Miceli, Francesco; Lesca, Gaetan; Beck, Anita E.; Sadleir, Lynette G.; Arrington, Daniel K.; Schonewolf-Greulich, Bitten; Moutton, Sebastien; Lauritano, Anna; Nappi, Piera; Soldovieri, Maria Virginia; Scheffer, Ingrid E.; Mefford, Heather C.; Stong, Nicholas; Heinzen, Erin L.; Goldstein, David B.; Perez, Ana Grijalvo; Kossoff, Eric H.; Stocco, Amber; Sullivan, Jennifer A.; Shashi, Vandana; Gerard, Benedicte; Francannet, Christine; Bisgaard, Anne-Marie; Tumer, Zeynep; Willems, Marjolaine; Rivier, Francois; Vitobello, Antonio; Thakkar, Kavita; Rajan, Deepa S.; Barkovich, A. James; Weckhuysen, Sarah; Cooper, Edward C.; Taglialatela, Maurizio; Cilio, M. Roberta
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy

奎尼丁早期治疗2例因功能获得性KCNT1突变引起的迁移性局灶性癫痫发作 (EIMFS) 的婴儿期癫痫患者: 功能研究，临床反应和个性化治疗的关键问题

NEUROTHERAPEUTICS
IF6.9
2018-10-0151
OAAI
Dilena, Robertino; DiFrancesco, Jacopo C.; Soldovieri, Maria Virginia; Giacobbe, Antonella; Ambrosino, Paolo; Mosca, Ilaria; Galli, Maria Albina; Guez, Sophie; Fumagalli, Monica; Miceli, Francesco; Cattaneo, Dario; Darra, Francesca; Gennaro, Elena; Zara, Federico; Striano, Pasquale; Castellotti, Barbara; Gellera, Cinzia; Varesio, Costanza; Veggiotti, Pierangelo; Taglialatela, Maurizio

研究方向

暂未获取到该数据
M
Maurizio Taglialatela
H 指数:65论文数:291被引数:1.1万
P
Paolo Ambrosino
H 指数:28论文数:60被引数:2,469
F
Francesco Miceli
H 指数:33论文数:90被引数:2,994
I
Ilaria Mosca
H 指数:17论文数:42被引数:844
V
Vincenzo Barrese
H 指数:22论文数:55被引数:1,579
N
Nunzio Iraci
H 指数:35论文数:103被引数:2,606
G
Giulia Bellini
H 指数:30论文数:73被引数:2,476
G
Gaëtan Lesca
H 指数:67论文数:447被引数:1.4万
B
Barbara Castellotti
H 指数:43论文数:156被引数:7,122
J
Jacopo C. DiFrancesco
H 指数:30论文数:109被引数:3,069