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K

Kimberly A. Foster

Bristol Myers Squibb
H指数:26
被引数:2,970
浏览量:0

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Utilizing Flux to Inform Formulation Strategy Decisions in Preclinical Studies

利用通量信息指导临床前研究中的配方策略决策

Molecular Pharmaceutics
IF4.5
2026-01-010
PRE
Mosquera-Giraldo, Laura I.; Patel, Zina; Yu, Dongyue; Ziemba, Theresa; Everlof, Gerry; Foster, Kimberly A.; Gesenberg, Christoph; Reid, Cameron; Sandhu, Bhupinder; Donoso, Maria; Chen, Xue-Qing
Hydrolysis of cellulose acetate phthalate and hydroxypropyl methylcellulose phthalate in amorphous solid dispersions
JOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
2025-01-010
PRE
Li, Jinghan; Yu, Dongyue; Zeng, Chaowang; Mosquera-Giraldo, Laura I.; Everlof, Gerry; Foster, Kimberly; Gesenberg, Christoph
Hexadecanoic acid mediated cell cycle arrest involving inhibition of cell migration
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Wright, Sasha-gay A.; Aiken, William; Asemota, Helen; Foster, Kimberly; Delgoda, Rupika
Discovery of 12 (BMS-986172) as a Highly Potent MGAT2 Inhibitor that Achieved Targeted Efficacious Exposures at a Low Human Dose for the Treatment of Metabolic Disorders
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-09-191
PRE
Meng, Wei; Brigance, Robert; Mignone, James; Negash, Lidet; Zhao, Guohua; Ahmad, Saleem; Wang, Wei; Moore, Fang; Ye, Xiang-Yang; Sun, Jung-Hui; Mathur, Arvind; Li, Yi-Xin; Azzara, Anthony; Ma, Zhengping; Chu, Ching-Hsuen; Cullen, Mary Jane; Rooney, Suzanne; Harvey, Susan; Kopcho, Lisa; Abell, Lynn; O'Malley, Kevin; Keim, William; Dierks, Elizabeth A.; Chang, Shu; Foster, Kimberly A.; Harden, David; Dabros, Marta; Goti, Vineet; De Oliveira, Claudia; Krishna, Gopal; Pelleymounter, Mary Ann; Whaley, Jean; Robl, Jeffrey A.; Cheng, Dong; Devasthale, Pratik
Optimization of physicochemical properties of pyrrolidine GPR40 AgoPAMs results in a differentiated profile with improved pharmacokinetics and reduced off-target activities
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2023-05-011
PRE
Jurica, Elizabeth A.; Wu, Ximao; Williams, Kristin N.; Haque, Lauren E.; Rampulla, Richard A.; Mathur, Arvind; Zhou, Min; Cao, Gary; Cai, Hong; Wang, Tao; Liu, Heng; Xu, Carrie; Kunselman, Lori K.; Antrilli, Thomas M.; Hicks, Michael B.; Sun, Qin; Dierks, Elizabeth A.; Apedo, Atsu; Moore, Douglas B.; Foster, Kimberly A.; Cvijic, Mary Ellen; Panemangalore, Reshma; Khandelwal, Purnima; Wilkes, Jason J.; Zinker, Bradley A.; Robertson, Donald G.; Janovitz, Evan B.; Galella, Michael; Li, Yi-Xin; Li, Julia; Ramar, Thangeswaran; Jalagam, Prasada Rao; Jayaram, Ramya; Whaley, Jean M.; Barrish, Joel C.; Robl, Jeffrey A.; Ewing, William R.; Ellsworth, Bruce A.
Enhanced aqueous dissolution of hydrophobic apixaban via direct incorporation of hydrophilic nanographene oxide
COLLOIDS AND SURFACES B-BIOINTERFACES
IF5.6
2022-08-015
PRE
Islam, Mohammad Saiful; Renner, Faradae; Foster, Kimberly; Oderinde, Martins S.; Stefanski, Kevin; Mitra, Somenath
Screening Hit to Clinical Candidate: Discovery of BMS-963272, a Potent, Selective MGAT2 Inhibitor for the Treatment of Metabolic Disorders
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-10-068
PREAI
Turdi, Huji; Chao, Hannguang; Hangeland, Jon J.; Ahmad, Saleem; Meng, Wei; Brigance, Robert; Zhao, Guohua; Wang, Wei; Moore, Fang; Ye, Xiang-Yang; Mathur, Arvind; Hou, Xiaoping; Kempson, James; Wu, Dauh-Rurng; Li, Yi-Xin; Azzara, Anthony, V; Ma, Zhengping; Chu, Ching-Hsuen; Chen, Luping; Cullen, Mary Jane; Rooney, Suzanne; Harvey, Susan; Kopcho, Lisa; Panemangelor, Reshma; Abell, Lynn; O'Malley, Kevin; Keim, William J.; Dierks, Elizabeth; Chang, Shu; Foster, Kimberly; Apedo, Atsu; Harden, David; Dabros, Marta; Gao, Qi; Pelleymounter, Mary Ann; Whaley, Jean M.; Robl, Jeffrey A.; Cheng, Dong; Lawrence, R. Michael; Devasthale, Pratik
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors

构象分析指导的2，3-二取代吡啶IDO1抑制剂的发现

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-06-162
OAAI
Cherney, Emily C.; Zhang, Liping; Guo, Weiwei; Huang, Audris; Williams, David; Seitz, Steven; Shan, Weifang; Zhu, Xiao; Gullo-Brown, Johnni; Maley, Derrick; Lin, Tai-an; Hunt, John T.; Huang, Christine; Yang, Zheng; D'Arienzo, Celia J.; Discenza, Lorell N.; Ranasinghe, Asoka; Grubb, Mary F.; Traeger, Sarah C.; Li, Xin; Johnston, Kathy A.; Kopcho, Lisa; Fereshteh, Mark; Foster, Kimberly A.; Stefanski, Kevin; Delpy, Diane; Dhar, Gopal; Anandam, Aravind; Mahankali, Sandeep; Padmanabhan, Shweta; Rajanna, Prabhakar; Murali, Venkata; Mariappan, T. Thanga; Pattasseri, Shabeerali; Nimje, Roshan Y.; Hong, Zhenqiu; Kempson, James; Rampulla, Richard; Mathur, Arvind; Gupta, Anuradha; Borzilleri, Robert; Vite, Gregory; Balog, Aaron
Solvent-Casted Films to Assist Polymer Selection for Amorphous Solid Dispersions During Preclinical Studies: In-vitro and In-vivo Exploration
PHARMACEUTICAL RESEARCH
IF4.3
2021-04-204
PREAI
Mosquera-Giraldo, Laura I.; Donoso, Maria; Stefanski, Kevin; Foster, Kimberly; Gesenberg, Christoph; Abraham, Pamela; Ren, Ying; Rose, Anne; Freeden, Chris; Ranasinghe, Asoka
Hydrophilic and Functionalized Nanographene Oxide Incorporated Faster Dissolving Megestrol Acetate
MOLECULES
IF4.6
2021-03-312
OAAI
Islam, Mohammad Saiful; Renner, Faradae; Foster, Kimberly; Oderinde, Martin S.; Stefanski, Kevin; Mitra, Somenath
Discovery and Preclinical Evaluation of BMS-986242, a Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1

BMS-986242的发现和临床前评估，一种有效的，选择性的Indoleamine-2，3-双加氧酶1抑制剂

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2021-01-2820
OA
Cherney, Emily C.; Zhang, Liping; Nara, Susheel; Zhu, Xiao; Gullo-Brown, Johnni; Maley, Derrick; Lin, Tai-An; Hunt, John T.; Huang, Christine; Yang, Zheng; Darienzo, Celia; Discenza, Lorell; Ranasinghe, Asoka; Grubb, Mary; Ziemba, Theresa; Traeger, Sarah C.; Li, Xin; Johnston, Kathy; Kopcho, Lisa; Fereshteh, Mark; Foster, Kimberly; Stefanski, Kevin; Fargnoli, Joseph; Swanson, Jesse; Brown, Jennifer; Delpy, Diane; Seitz, Steven P.; Borzilleri, Robert; Vite, Gregory; Balog, Aaron
CBFB-MYH11 fusion neoantigen enables T cell recognition and killing of acute myeloid leukemia
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-08-2453
OA
Biernacki, Melinda A.; Foster, Kimberly A.; Woodward, Kyle B.; Coon, Michael E.; Cummings, Carrie; Cunningham, Tanya M.; Dossa, Robson G.; Brault, Michelle; Stokke, Jamie; Olsen, Tayla M.; Gardner, Kelda; Estey, Elihu; Meshinchi, Soheil; Rongvaux, Anthony; Bleakley, Marie
Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-01-2724
PREAI
Shi, Jun; Gu, Zhengxiang; Jurica, Elizabeth Anne; Wu, Ximao; Haque, Lauren E.; Williams, Kristin N.; Hernandez, Andres S.; Hong, Zhenqiu; Gao, Qi; Dabros, Marta; Davulcu, Akin H.; Mathur, Arvind; Rampulla, Richard A.; Gupta, Arun Kumar; Jayaram, Ramya; Apedo, Atsu; Moore, Douglas B.; Liu, Heng; Kunselman, Lori K.; Brady, Edward J.; Wilkes, Jason J.; Zinker, Bradley A.; Cai, Hong; Shu, Yue-Zhong; Sun, Qin; Dierks, Elizabeth A.; Foster, Kimberly A.; Xu, Carrie; Wang, Tao; Panemangalore, Reshma; Cvijic, Mary Ellen; Xie, Chunshan; Cao, Gary G.; Zhou, Min; Krupinski, John; Whaley, Jean M.; Robl, Jeffrey A.; Ewing, William R.; Ellsworth, Bruce Alan
ABRUPT CLINICAL ONSET OF CHIARI MALFORMATION TYPE 1 FOLLOWING MINOR TRAUMA IN A PEDIATRIC PATIENT
CRITICAL CARE MEDICINE
IF6
2018-01-010
PREAI
Mohammad, Laila; Foster, Kimberly; Agarwal, Hemant
SURGICAL DECOMPRESSION OF CHIARI II MALFORMATION IN EARLY INFANCY FOR SEVERE SLEEP APNEA
CRITICAL CARE MEDICINE
IF6
2018-01-010
PREAI
Mohammad, Laila; Foster, Kimberly; Agarwal, Hemant
Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance
JOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
2018-01-0161
OAAI
Chen, Huijun; Pui, Yipshu; Liu, Chengyu; Chen, Zhen; Su, Ching-Chiang; Hageman, Michael; Hussain, Munir; Haskell, Roy; Stefanski, Kevin; Foster, Kimberly; Gudmundsson, Olafur; Qian, Feng
Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT2C Receptor Agonists
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-07-0714
PREAI
Carpenter, Joseph; Wang, Ying; Wu, Gang; Feng, Jianxin; Ye, Xiang-Yang; Morales, Christian L.; Broekema, Matthias; Rossi, Karen A.; Miller, Keith J.; Murphy, Brian J.; Wu, Ginger; Malmstrom, Sarah E.; Azzara, Anthony V.; Sher, Philip M.; Fevig, John M.; Alt, Andrew; Bertekap, Robert L., Jr.; Cullen, Mary Jane; Harper, Timothy M.; Foster, Kimberly; Luk, Emily; Xiang, Qian; Grubb, Mary F.; Robl, Jeffrey A.; Wacker, Dean A.
A Novel Regulatory Cascade Involving BluR, YcgZ, and Lon Controls the Expression of Escherichia coli OmpF Porin
FRONTIERS IN MICROBIOLOGY
IF4.5
2017-06-308
OAAI
Duval, Valerie; Foster, Kimberly; Brewster, Jennifer; Levy, Stuart B.
Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding Mode
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-02-0925
PREAI
Jurica, Elizabeth A.; Wu, Ximao; Williams, Kristin N.; Hernandez, Andres S.; Nirschl, David S.; Rampulla, Richard A.; Mathur, Arvind; Zhou, Min; Cao, Gary; Xie, Chunshan; Jacob, Biji; Cai, Hong; Wang, Tao; Murphy, Brian J.; Liu, Heng; Xu, Carrie; Kunselman, Lori K.; Hicks, Michael B.; Sun, Qin; Schnur, Dora M.; Sitkoff, Doree F.; Dierks, Elizabeth A.; Apedo, Atsu; Moore, Douglas B.; Foster, Kimberly A.; Cvijic, Mary Ellen; Panemangalore, Reshma; Flynn, Neil A.; Maxwell, Brad D.; Hong, Yang; Tian, Yuan; Wilkes, Jason J.; Zinker, Bradley A.; Whaley, Jean M.; Barrish, Joel C.; Robl, Jeffrey A.; Ewing, William R.; Ellsworth, Bruce A.
Inhibition of PI3K/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in established and primary cultured glioblastoma cells
CANCER RESEARCH
IF16.6
2014-10-010
PRE
Jane, Esther P.; Premkumar, Daniel R.; Morales, Alejandro; Foster, Kimberly A.; Pollack, Ian

研究方向

暂未获取到该数据
A
Arvind Mathur
H 指数:32论文数:267被引数:3,431
J
Jeffrey A. Robl
H 指数:32论文数:164被引数:4,461
K
Kevin Stefanski
H 指数:16论文数:50被引数:1,487
D
Daniel R. Premkumar
H 指数:29论文数:108被引数:2,451
E
Elizabeth A. Dierks
H 指数:18论文数:42被引数:1,274
I
Ian F. Pollack
H 指数:95论文数:729被引数:3.1万
E
Esther P. Jane
H 指数:19论文数:124被引数:1,289
J
Jean M. Whaley
H 指数:27论文数:61被引数:5,782
M
Mary Ellen Cvijic
H 指数:27论文数:199被引数:2,661
L
Lisa M. Kopcho
H 指数:17论文数:60被引数:818