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Nociceptors are functionally male or female: from mouse to monkey to man Stratton, Harrison; Lee, Grace; Dolatyari, Mahdi; Ghetti, Andre; Cotta, Tamara; Mitchell, Stefanie; Yue, Xu; Ibrahim, Mohab; Dumaire, Nicolas; Salih, Lyuba; Moutal, Aubin; Francois-Moutal, Liberty; Martin, Laurent; Navratilova, Edita; Porreca, Frank 分享 收藏
Identification and targeting of a unique NaV1.7 domain driving chronic pain Gomez, Kimberly; Stratton, Harrison J.; Duran, Paz; Loya, Santiago; Tang, Cheng; Calderon-Rivera, Aida; Francois-Moutal, Liberty; Khanna, May; Madura, Cynthia L.; Luo, Shizhen; McKiver, Bryan; Choi, Edward; Ran, Dongzhi; Boinon, Lisa; Perez-Miller, Samantha; Damaj, M. Imad; Moutal, Aubin; Khanna, Rajesh 分享 收藏
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Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology Francois-Moutal, Liberty; Scott, David Donald; Ambrose, Andrew J.; Zerio, Christopher J.; Rodriguez-Sanchez, Marina; Dissanayake, Kumara; May, Danielle G.; Carlson, Jacob M.; Barbieri, Edward; Moutal, Aubin; Roux, Kyle J.; Shorter, James; Khanna, Rajesh; Barmada, Sami J.; McGurk, Leeanne; Khanna, May 分享 收藏
Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents Cai, Song; Moutal, Aubin; Yu, Jie; Chew, Lindsey A.; Isensee, Jorg; Chawla, Reena; Gomez, Kimberly; Luo, Shizhen; Zhou, Yuan; Chefdeville, Aude; Madura, Cynthia; Perez-Miller, Samantha; Bellampalli, Shreya Sai; Dorame, Angie; Scott, David D.; Francois-Moutal, Liberty; Shan, Zhiming; Woodward, Taylor; Gokhale, Vijay; Hohmann, Andrea G.; Vanderah, Todd W.; Patek, Marcel; Khanna, May; Hucho, Tim; Khanna, Rajesh 分享 收藏
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An Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43 Yields Neuroprotective Properties Mollasalehi, Niloufar; Francois-Moutal, Liberty; Scott, David D.; Tello, Judith A.; Williams, Haley; Mahoney, Brendan; Carlson, Jacob M.; Dong, Yue; Li, Xingli; Miranda, Victor G.; Gokhale, Vijay; Wang, Wei; Barmada, Sami J.; Khanna, May 分享 收藏
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The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels Zhou, Yuan; Cai, Song; Moutal, Aubin; Yu, Jie; Gomez, Kimberly; Madura, Cynthia L.; Shan, Zhiming; Pham, Nancy Y. N.; Serafini, Maria J.; Dorame, Angie; Scott, David D.; Francois-Mouta, Liberty; Perez-Miller, Samantha; Patek, Marcel; Khanna, May; Khanna, Rajesh 分享 收藏
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Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS) Francois-Moutal, Liberty; Felemban, Razaz; Scott, David D.; Sayegh, Melissa R.; Miranda, Victor G.; Perez-Miller, Samantha; Khanna, Rajesh; Gokhale, Vijay; Zarnescu, Daniela C.; Khanna, May 分享 收藏
A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B) 一种化学生物学方法来模拟1B型小脑发育不全 (PCH1B) Francois-Moutal, Liberty; Jahanbakhsh, Shahriyar; Nelson, Andrew D. L.; Ray, Debashish; Scott, David D.; Hennefarth, Matthew R.; Moutal, Aubin; Perez-Miller, Samantha; Ambrose, Andrew J.; Al-Shamari, Ahmed; Coursodon, Philippe; Meechoovet, Bessie; Reiman, Rebecca; Lyons, Eric; Beilstein, Mark; Chapman, Eli; Morris, Quaid D.; Van Keuren-Jensen, Kendall; Hughes, Timothy R.; Khanna, Rajesh; Koehler, Carla; Jen, Joanna; Gokhale, Vijay; Khanna, May 分享 收藏
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Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain Francois-Moutal, Liberty; Dustrude, Erik T.; Wang, Yue; Brustovetsky, Tatiana; Dorame, Angie; Ju, Weina; Moutal, Aubin; Perez-Miller, Samantha; Brustovetsky, Nickolay; Gokhale, Vijay; Khanna, May; Khanna, Rajesh 分享 收藏
CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide Moutal, Aubin; Yang, Xiaofang; Li, Wennan; Gilbraith, Kerry B.; Luo, Shizhen; Cai, Song; Francois-Moutal, Liberty; Chew, Lindsey A.; Yeon, Seul Ki; Bellampalli, Shreya S.; Qu, Chaoling; Xie, Jennifer Y.; Ibrahim, Mohab M.; Khanna, May; Park, Ki Duk; Porreca, Frank; Khanna, Rajesh 分享 收藏
Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides Moutal, Aubin; Li, Wennan; Wang, Yue; Ju, Weina; Luo, Shizhen; Cai, Song; Francois-Moutal, Liberty; Perez-Miller, Samantha; Hu, Jackie; Dustrude, Erik T.; Vanderah, Todd W.; Gokhale, Vijay; Khanna, May; Khanna, Rajesh 分享 收藏
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