未登录 USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer USP10/GSK3β介导的PTEN抑制驱动乳腺癌对PI3K抑制剂的耐药性 Kumari, Nishi; Wright, Sarah C. E.; Witham, Christopher M.; Monserrat, Laia; Palafox, Marta; Richard, John L. C.; Costa, Carlotta; Elkabets, Moshe; Agostino, Mark; Klemm, Theresa; Eccles, Melissa; Garnham, Alex; Wu, Ting; Nilsson, Jonas A.; Walz, Nikita; Venugopal, Veena; Cerra, Anthony; Vasilevski, Natali; Bridgeman, Stephanie; Bassi, Sona; Saei, Azad; Helal, Moutaz; Neundorf, Philipp; Riedel, Angela; Rosenfeldt, Mathias; Gill, Jespal; Pahor, Nikolett; Hartmann, Oliver; Chung, Jacky; Sidhu, Sachdev S.; Moderau, Nina; Jha, Sudhakar; Rodon, Jordi; Diefenbacher, Markus E.; Komander, David; Serra, Violeta; Eichhorn, Pieter Johan Adam 分享 收藏
Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition 代谢依赖性分析确定了Peroxiredoxin 1是ATM抑制的驱动因素。 Li, Haojian; Furusawa, Takashi; Cavero, Renzo; Xiao, Yunjie; Chari, Raj; Wu, Xiaolin; Sun, David; Hartmann, Oliver; Dhall, Anjali; Holewinski, Ronald; Andresson, Thorkell; Karim, Baktiar; Villamor-Paya, Marina; Gallardo, Devorah; Day, Chi-Ping; Pal, Lipika R.; Nair, Nishanth Ulhas; Ruppin, Eytan; Aladjem, Mirit I.; Pommier, Yves; Villamor-Paya, Marina; Diefenbacher, Markus E.; Lim, Jung Mi; Levine, Rodney L.; Stracker, Travis H. 分享 收藏
Proenkephalin improves risk prediction in acute coronary syndromes: derivation and external validation of the KID-ACS risk score Wenzl, F. A.; Wang, P.; Arrigo, M.; Parenica, J.; Jones, D. J. L.; Hartmann, O.; Kraler, S.; Camici, G. G.; Bergmann, A.; Cao, T. H.; Roffi, M.; Raeber, L.; Mebazaa, A.; Ng, L. L.; Luescher, T. F. 分享 收藏
Adjustment of the SMART risk score by bioactive adrenomedullin enables a more accurate prediction of mortality in patients with ASCVD Kurt, B.; Rau, M.; Hartmann, O.; De Sa, F. Lobo; Moellmann, J.; Spiesshoefer, J.; Milzi, A.; Schwarz, M.; Thiele, K.; Hartmann, N.; Van Der Vorst, E.; Dahl, E.; Marx, N.; Lehrke, M.; Kahles, F. 分享 收藏
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer Reissland, Michaela; Hartmann, Oliver; Tauch, Saskia; Bugter, Jeroen M.; Prieto-Garcia, Cristian; Schulte, Clemens; Loebbert, Sinah; Solvie, Daniel; Bitman-Lotan, Eliya; Narain, Ashwin; Jacomin, Anne-Claire; Schuelein-Voelk, Christina; Fuss, Carmina T.; Pahor, Nikolett; Ade, Carsten; Buck, Viktoria; Potente, Michael; Li, Vivian; Beliu, Gerti; Wiegering, Armin; Grossmann, Tom; Eilers, Martin; Wolf, Elmar; Maric, Hans; Rosenfeldt, Mathias; Maurice, Madelon M.; Dikic, Ivan; Gallant, Peter; Orian, Amir; Diefenbacher, Markus E. 分享 收藏
Proenkephalin A 119-159 (penKid) and mortality in stable patients at high cardiovascular risk Rau, Matthias; Kurt, Berkan; Hartmann, Oliver; de Sa, Fabia Daniela Lobo; Schwarz, Marvin; Thiele, Kirsten; Hartmann, Niels-Ulrik Korbinian; Spiesshoefer, Jens; Moellmann, Julia; Hohl, Mathias; Selejan, Simina-Ramona; van der Vorst, Emiel P. C.; Dahl, Edgar; Marx, Nikolaus; Kahles, Florian; Lehrke, Michael 分享 收藏
Proenkephalin improves cardio-renal risk prediction in acute coronary syndromes: the KID-ACS score 前脑啡肽可改善急性冠脉综合征的心肾风险预测: kid-acs评分 Wenzl, Florian A.; Wang, Peizhi; Arrigo, Mattia; Parenica, Jiri; Jones, Donald J. L.; Bruno, Francesco; Tarnowski, Daniel; Hartmann, Oliver; Boucek, Lubos; Lang, Fabian; Obeid, Slayman; Schober, Andreas; Kraler, Simon; Akhmedov, Alexander; Kahles, Florian; Schober, Alexander; Ow, Kok Weng; Ministrini, Stefano; Camici, Giovanni G.; Bergmann, Andreas; Liberale, Luca; Jarkovsky, Jiri; Schweiger, Victor; Sandhu, Jatinderpal K.; von Eckardstein, Arnold; Templin, Christian; Muller, Olivier; Ondrus, Tomas; Olic, Janet-Jacqueline; Roffi, Marco; Raeber, Lorenz; Cao, Thong H.; Jungbauer, Carsten G.; Ng, Leong L.; Mebazaa, Alexandre; Luescher, Thomas F. 分享 收藏
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ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP Abbas, Ruqaia; Hartmann, Oliver; Asiss, Dorin Theodora; Abbas, Rabab; Kagan, Julia; Kim, Hyoung-Tae; Oren, Moshe; Diefenbacher, Markus; Orian, Amir; Larisch, Sarit 分享 收藏
Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer Furusawa, Takashi; Cavero, Renzo; Liu, Yue; Li, Haojian; Xu, Xia; Andresson, Thorkell; Reinhold, William; White, Olivia; Boufraqech, Myriem; Meyer, Thomas J.; Hartmann, Oliver; Diefenbacher, Markus E.; Pommier, Yves; Weyemi, Urbain 分享 收藏
Bioactive adrenomedullin (bio-ADM) is associated with endothelial dysfunction in infants and children with complex congenital heart disease undergoing open-heart surgery on cardiopulmonary bypass Schaefer, Maike; Stein, Andreas; Ruf, Bettina; Balling, Gunter; Palm, Jonas; Simmelbauer, Andreas; Cleuziou, Julie; Sander, Michaela; Auer, Josef; Borgmann, Kristina; Struck, Joachim; Hartmann, Oliver; Schulte, Janin; Hoerer, Juergen; Tassani-Prell, Peter; Ewert, Peter; Holdenrieder, Stefan; Wolf, Cordula M. 分享 收藏
DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma Strubel, Alexander; Muenick, Philipp; Hartmann, Oliver; Chaikuad, Apirat; Dreier, Birgit; Schaefer, Jonas V.; Gebel, Jakob; Osterburg, Christian; Tuppi, Marcel; Schaefer, Birgit; Buck, Viktoria; Rosenfeldt, Mathias; Knapp, Stefan; Pluckthun, Andreas; Diefenbacher, Markus E.; Doetsch, Volker 分享 收藏
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Effects of enrichment strategies on outcome of adrecizumab treatment in septic shock: Post-hoc analyses of the phase II adrenomedullin and outcome in septic shock 2 trial 富集策略对脓毒症休克adrecizumab治疗结局的影响: II期肾上腺髓质素和脓毒症休克2试验结局的事后分析 van Lier, Dirk; Picod, Adrien; Marx, Gernot; Laterre, Pierre-Francois; Hartmann, Oliver; Knothe, Claudia; Azibani, Feriel; Struck, Joachim; Santos, Karine; Zimmerman, Jens; Bergmann, Andreas; Mebazaa, Alexandre; Pickkers, Peter 分享 收藏
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Growth hormone concentration and risk of all-cause and cardiovascular mortality: The REasons for Geographic And Racial Disparities in Stroke (REGARDS) study Wettersten, Nicholas; Mital, Rohit; Cushman, Mary; Howard, George; Judd, Suzanne E.; Howard, Virginia J.; Safford, Monika M.; Hartmann, Oliver; Bergmann, Andreas; Struck, Joachim; Maisel, Alan 分享 收藏
RNF4∼RGMb∼BMP6 axis required for osteogenic differentiation and cancer cell survival Novak, Rostislav; Abu Ahmad, Yamen; Timaner, Michael; Bitman-Lotan, Eliya; Oknin-Vaisman, Avital; Horwitz, Roi; Hartmann, Oliver; Reissland, Michaela; Buck, Viktoria; Rosenfeldt, Mathias; Nikomarov, David; Diefenbacher, Markus Elmar; Shaked, Yuval; Orian, Amir 分享 收藏
Bioactive adrenomedullin for assessment of venous congestion in heart failure Egerstedt, Anna; Czuba, Tomasz; Bronton, Kevin; Lejonberg, Carl; Ruge, Thoralph; Wessman, Torgny; Radegran, Goran; Schulte, Janin; Hartmann, Oliver; Melander, Olle; Smith, J. Gustav 分享 收藏
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K Prieto-Garcia, Cristian; Hartmann, Oliver; Reissland, Michaela; Braun, Fabian; Bozkurt, Suleyman; Pahor, Nikolett; Fuss, Carmina; Schirbel, Andreas; Schuelein-Voelk, Christina; Buchberger, Alexander; Canale, Marco A. Calzado; Rosenfeldt, Mathias; Dikic, Ivan; Muench, Christian; Diefenbacher, Markus E. 分享 收藏
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