Claire Lugnier - Publications, H-index & Citations

Claire Lugnier

universite de orleans

46H指数

195论文数

7.2K被引数

收录论文 55

发表时间

PDE4 inhibition as a therapeutic strategy for improvement of pulmonary dysfunctions in Covid-19 and cigarette smoking

BIOCHEMICAL PHARMACOLOGY

IF5.6

2021-03-01

OAAI

Lugnier, Claire; Al-Kuraishy, Hayder M.; Rousseau, Eric

Cyclic nucleotide phosphodiesterases: New targets in the metabolic syndrome?环核苷酸磷酸二酯酶: 代谢综合征的新靶点？

PHARMACOLOGY & THERAPEUTICS

IF12.5

2020-04-01

PREAI

Lugnier, Claire; Meyer, Alain; Talha, Samy; Geny, Bernard

The Endocrine Function of the Heart: Physiology and Involvements of Natriuretic Peptides and Cyclic Nucleotide Phosphodiesterases in Heart Failure

JOURNAL OF CLINICAL MEDICINE

IF2.9

2019-10-21

OAAI

Lugnier, Claire; Meyer, Alain; Charloux, Anne; Andres, Emmanuel; Geny, Bernard; Talha, Samy

Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-09-01

OAAI

Bollenbach, Maud; Lugnier, Claire; Kremer, Melanie; Salvat, Eric; Megat, Salim; Bihel, Frederic; Bourguignon, Jean-Jacques; Barrot, Michel; Schmitt, Martine

Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress

ANTIOXIDANTS

IF6.6

2019-04-07

OAAI

Tetsi, Liliane; Charles, Anne-Laure; Georg, Isabelle; Goupilleau, Fabienne; Lejay, Anne; Talha, Samy; Maumy-Bertrand, Myriam; Lugnier, Claire; Geny, Bernard

VEGF-induced HUVEC migration and proliferation are decreased by PDE2 and PDE4 inhibitors

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-12-06

105

PREAI

Favot, L; Keravis, T; Holl, V; Le Bec, A; Lugnier, C

Modulation of VEGF-induced endothelial cell cycle protein expression through cyclic AMP hydrolysis by PDE2 and PDE4 PDE2和PDE4通过环AMP水解调节VEGF诱导的内皮细胞周期蛋白表达

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-11-30

PREAI

Favot, L; Keravis, T; Lugnier, C

Tumour growth inhibition and anti-angiogenic effects using curcumin correspond to combined PDE2 and PDE4 inhibition

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-11-27

PREAI

Abusnina, Abdurazzag; Keravis, Therese; Zhou, Qingwei; Justiniano, Helene; Lobstein, Annelise; Lugnier, Claire

Therapeutic potentials of natural compounds acting on cyclic nucleotide phosphodiesterase families

CELLULAR SIGNALLING

IF3.7

2017-11-01

PREAI

Abusnina, Abdurazzag; Lugnier, Claire

Endothelium-independent vasorelaxant effect of Thymus linearis via inhibition of phosphodiesterases in porcine coronary artery

BIOCHEMICAL PHARMACOLOGY

IF5.6

2017-09-01

PREAI

Alamgeer, Alamgeer; Auger, Cyril; Chabert, P.; Lugnier, C.; Schini-Kerth, V. B.

Effects of cyclic nucleotide phosphodiesterases (PDEs) on mitochondrial skeletal muscle functions

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2016-12-30

PREAI

Tetsi, Liliane; Charles, Anne-Laure; Paradis, Stephanie; Lejay, Anne; Talha, Samy; Geny, Bernard; Lugnier, Claire

Endothelium-independent vasorelaxant effect of a Berberis orthobotrys root extract via inhibition of phosphodiesterases in the porcine coronary artery

PHYTOMEDICINE

IF8.3

2016-07-01

OAAI

Alamgeer; Chabert, P.; Akhtar, M. S.; Jabeen, Q.; Delecolle, J.; Heintz, D.; Garo, E.; Hamburger, M.; Auger, C.; Lugnier, C.; Kim, H. -J.; Oak, M. -H.; Schini-Kerth, V. B.

Design, Synthesis, and Pharmacological Evaluation of N-Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase-4 Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2012-08-30

110

PREAI

Kuemmerle, Arthur E.; Schmitt, Martine; Cardozo, Suzana V. S.; Lugnier, Claire; Villa, Pascal; Lopes, Alexandra B.; Romeiro, Nelilma C.; Justiniano, Helene; Martins, Marco A.; Fraga, Carlos A. M.; Bourguignon, Jean-Jacques; Barreiro, Eliezer J.

Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2012-02-10

316

OAAI

Keravis, Therese; Lugnier, Claire

Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation

INVESTIGATIONAL NEW DRUGS

IF2.7

2011-12-15

PREAI

Kolli-Bouhafs, Kaouther; Boukhari, Abdelaziz; Abusnina, Abdurazzag; Velot, Emilie; Gies, Jean-Pierre; Lugnier, Claire; Ronde, Philippe

PDE inhibitors: a new approach to treat metabolic syndrome?

CURRENT OPINION IN PHARMACOLOGY

IF4.2

2011-12-01

PREAI

Lugnier, Claire

NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2011-10-01

PREAI

Yougbare, Issaka; Morin, Caroline; Senouvo, Farid Yannick; Sirois, Chantal; Albadine, Roula; Lugnier, Claire; Rousseau, Eric

Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis

CELLULAR SIGNALLING

IF3.7

2011-01-01

PREAI

Abusnina, Abdurazzag; Alhosin, Mahmoud; Keravis, Therese; Muller, Christian D.; Fuhrmann, Guy; Bronner, Christian; Lugnier, Claire

Novel thienylacylhydrazone derivatives inhibit platelet aggregation through cyclic nucleotides modulation and thromboxane A2 synthesis inhibition

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2010-07-01

OAAI

Brito, Fernanda C. F.; Kummerle, Arthur E.; Lugnier, Claire; Fraga, Carlos A. M.; Barreiro, Eliezer J.; Miranda, Ana L. P.

The flavonoid dioclein reduces the production of pro-inflammatory mediators in vitro by inhibiting PDE4 activity and scavenging reactive oxygen species

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2010-05-01

OAAI

Guabiraba, Rodrigo; Campanha-Rodrigues, Ana Lucia; Souza, Adriano L. S.; Santiago, Helton C.; Lugnier, Claire; Alvarez-Leite, Jacqueline; Lemos, Virginia S.; Teixeira, Mauro M.

研究方向