未登录 C22-to C26,27-Fluoro-2-(3-hydroxypropyl)-19-norvitamin D 3 , Side-chain Fluorinated MART-10s Suppress IL-19 Secretion from Th17-stimulated Keratinocytes: Potent Therapeutic Effects on Psoriasis Models C22至C26,27-氟代-2-(3-羟基丙基)-19-去甲维生素D3，侧链氟化的MART-10s抑制Th17刺激的角质形成细胞分泌IL-19：对银屑病模型的显著治疗效果 Kawagoe, Fumihiro; Mototani, Sayuri; Yamaguchi, Mana; Takeuchi, Akiko; Yatsu, Tomofumi; Yasuda, Kaori; Takano, Masashi; Akagi, Yusuke; Fujishima, Toshie; Miyata, Yoshiki; Saitoh, Hiroshi; Sakaki, Toshiyuki; Kittaka, Atsushi 分享 收藏
Synthesis of 23,23-Difluoro-24-nor- and 24′,24′-Difluoro-24-Homovitamin D3 Analogues and Unexpected Structure-Activity Relationships 23,23-二氟-24-降-和24′,24′-二氟-24-高维生素D3类似物的合成及意外的构效关系 Kawagoe, Fumihiro; Tabuchi, Hiroya; Ideguchi, Taiyo; Okamoto, Yuki; Murata, Souma; Yatsu, Tomofumi; Yamada, Syota; Yasuda, Kaori; Akagi, Yusuke; Takano, Masashi; Fujishima, Toshie; Miyata, Yoshiki; Aoki, Ken'ichi; Sakaki, Toshiyuki; Kittaka, Atsushi 分享 收藏
Comprehensive Synthesis of Side-Chain Fluorinated 2α-[2-(Tetrazol-2-yl)ethyl]-1α, 25-dihydroxyvitamin D3 Analogs and Preliminary Biological Activities 侧链氟化的2α-[2-(四唑-2-基)乙基]-1α,25-二羟基维生素D3类似物的全面合成及初步生物活性 Kawagoe, Fumihiro; Mototani, Sayuri; Okamoto, Yuki; Murata, Souma; Takeuchi, Akiko; Yatsu, Tomofumi; Yasuda, Kaori; Akagi, Yusuke; Fujishima, Toshie; Miyata, Yoshiki; Saitoh, Hiroshi; Sakaki, Toshiyuki; Kittaka, Atsushi 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
Structure-Function Analysis of Streptomyces griseolus CYP105A1 in the Metabolism of Nonsteroidal Anti-inflammatory Drugs 灰链霉菌CYP105A1的结构-功能分析及其在非甾体抗炎药物代谢中的作用 Takita, Teisuke; Wada, Moeka; Yamagata, Masaya; Kamata, Seiei; Mizutani, Kimihiko; Yogo, Yuya; Hamada, Masahiro; Yasuda, Kaori; Mikami, Bunzo; Sakaki, Toshiyuki; Yasukawa, Kiyoshi 分享 收藏
Gene therapy for alopecia in type II rickets model rats using vitamin D receptor-expressing adenovirus vector Kise, Satoko; Iijima, Ayano; Nagao, Chika; Okada, Tadashi; Nishikawa, Miyu; Ikushiro, Shinichi; Nakanishi, Tomoko; Sato, Shigeto; Yasuda, Kaori; Sakaki, Toshiyuki 分享 收藏
Synthesis of (22R)-, (22S)-22-Fluoro-, and 22,22-Difluoro-25-hydroxyvitamin D3 and Effects of Side-Chain Fluorination on Biological Activity and CYP24A1-Dependent Metabolism Kawagoe, Fumihiro; Mototani, Sayuri; Yasuda, Kaori; Takeuchi, Akiko; Mano, Hiroki; Kakuda, Shinji; Saitoh, Hiroshi; Sakaki, Toshiyuki; Kittaka, Atsushi 分享 收藏
分享 收藏
Hydroxylation and dechlorination of 3,3′,4,4′-tetrachlorobiphenyl (CB77) by rat and human CYP1A1s and critical roles of amino acids composing their substrate-binding cavity Yabu, Miku; Haga, Yuki; Itoh, Toshimasa; Goto, Erika; Suzuki, Motoharu; Yamazaki, Kiyoshi; Mise, Shintaro; Yamamoto, Keiko; Matsumura, Chisato; Nakano, Takeshi; Sakaki, Toshiyuki; Inui, Hideyuki 分享 收藏
分享 收藏
分享 收藏
Novel DNA Aptamer for CYP24A1 Inhibition with Enhanced Antiproliferative Activity in Cancer Cells Biyani, Madhu; Yasuda, Kaori; Isogai, Yasuhiro; Okamoto, Yuki; Weilin, Wei; Kodera, Noriyuki; Flechsig, Holger; Sakaki, Toshiyuki; Nakajima, Miki; Biyani, Manish 分享 收藏
分享 收藏
Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by CYP24A1 and CYP3A using Cyp24a1 knockout rats generated by CRISPR/Cas9 system Yasuda, Kaori; Nishikawa, Miyu; Okamoto, Kairi; Horibe, Kyohei; Mano, Hiroki; Yamaguchi, Mana; Okon, Risa; Nakagawa, Kimie; Tsugawa, Naoko; Okano, Toshio; Kawagoe, Fumihiro; Kittaka, Atsushi; Ikushiro, Shinichi; Sakaki, Toshiyuki 分享 收藏
分享 收藏
Generation of novel genetically modified rats to reveal the molecular mechanisms of vitamin D actions Nishikawa, Miyu; Yasuda, Kaori; Takamatsu, Masashi; Abe, Keisuke; Okamoto, Kairi; Horibe, Kyohei; Mano, Hiroki; Nakagawa, Kimie; Tsugawa, Naoko; Hirota, Yoshihisa; Horie, Tetsuhiro; Hinoi, Eiichi; Okano, Toshio; Ikushiro, Shinichi; Sakaki, Toshiyuki 分享 收藏
分享 收藏
.png){kind=icon}
.png){kind=icon}
.png)
Synlett.png)
.png){kind=icon}
分享.png){kind=icon}
收藏
