未登录

L

Lailiang Qu

Xinyang Normal University

H指数:16

被引数:687

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Novel pyrazole-4-carboxamides containing a piperazine moiety: Synthesis, crystal structure, antifungal activity, molecular docking, DFT and ESP calculations

含哌嗪基团的新型吡唑-4-甲酰胺：合成、晶体结构、抗真菌活性、分子对接、DFT和ESP计算

Journal of Molecular Structure

IF4.7

2025-09-220

PRE

Design and Synthesis of Novel MEK Inhibitors for the Treatment of Solid Tumors

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2025-02-190

PRE

Novel Pyrazole-4-Carboxamide Derivatives Containing Oxime Ether Group as Potential SDHIs to Control Rhizoctonia solani

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2024-04-224

PRE

Stereoselective Synthesis of β, γ-Fused Bicyclic γ-Ureasultams via an Intramolecular Mannich and aza-Michael Addition Cascade

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2024-04-052

PRE

Novel pyrazole-4-carboxamides and aromatic carboxamides derivatives containing a hydrazine moiety as potential SDHIs

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2023-11-013

PRE

Design, Synthesis, and Antifungal Activities of Novel Pyrazole-4-carboxamide Derivatives Containing an Ether Group as Potential Succinate Dehydrogenase Inhibitors

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2023-06-0726

PRE

Histone Deacetylase and Enhancer of Zeste Homologue 2 Dual Inhibitors Presenting a Synergistic Effect for the Treatment of Hematological Malignancies

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-09-2520

PRE

Discovery of precision targeting EZH2 degraders for triple-negative breast cancer

发现针对三阴性乳腺癌的精确靶向EZH2降解剂

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-08-0131

PRE

Novel insights into RIPK1 as a promising target for future Alzheimer's disease treatment

PHARMACOLOGY & THERAPEUTICS

IF12.5

2022-03-0129

PRE

Discovery of PT-65 as a highly potent and selective Proteolysis-targeting chimera degrader of GSK3 for treating Alzheimer's disease

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-12-0129

PRE

Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-12-0119

PREAI

Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-08-2944

PREAI

Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer's disease

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-07-0133

PREAI

Identification and optimization of piperlongumine analogues as potential antioxidant and anti-inflammatory agents via activation of Nrf2

通过激活Nrf2鉴定和优化胡椒碱类似物作为潜在的抗氧化剂和抗炎剂

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-01-0128

PREAI

Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-01-0118

PREAI

Usnic acid derivatives as tau-aggregation and neuroinflammation inhibitors

松萝酸衍生物作为tau聚集和神经炎症抑制剂

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-02-0129

PREAI

Natural products as sources of new antioxidants: Synthesis and antioxidant evaluation of Mannich bases of novel sesamol derivatives

INDUSTRIAL CROPS AND PRODUCTS

IF6.2

2019-12-0110

PREAI

A hemicyanine derivative for near-infrared imaging of β-amyloid plaques in Alzheimer's disease

用于阿尔茨海默氏病 β-淀粉样斑块的近红外成像的半丙氨酸衍生物

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-10-0124

PREAI

Application of Sustainable Natural Bioresources in Agriculture: Iodine-Mediated Oxidative Cyclization for Metal-Free One-Pot Synthesis of N-Phenylpyrazole Sarisan Analogues as Insecticidal Agents

IF4.3

2017-09-2018

OAAI