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J

Johan Broddefalk

medicinal chemistry, astrazeneca, gothenburg 431 53, sweden
H指数:15
被引数:899

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Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15–GFRaL–RET Complex Cell Signaling

双环肽串联的设计:模拟同源二聚体GDF15蛋白以抑制GDF15–GFRaL–RET复合物细胞信号传导

2025-10-090
PRE
Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell
2021-02-2440
PREAI
Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease
2019-03-1430
PREAI
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors
2018-06-239
OAAI
Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid
2018-06-235
OAAI
Discovery of AZD6642, an Inhibitor of 5-Lipoxygenase Activating Protein (FLAP) for the Treatment of Inflammatory Diseases
2014-12-2238
PREAI
Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats
2011-05-0138
PRE