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Bruno, Agostino

ifom - firc institute of molecular oncology

H指数:0

被引数:4

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Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4

基于结构的HECT连接酶NEDD4的高效且选择性抑制剂的构效关系设计

COMMUNICATIONS CHEMISTRY

IF6.2

2025-05-280

OA

Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria

具有环丙烷羧酸支架的O-乙酰丝氨酸巯基化酶抑制剂是革兰氏阴性细菌中有效的粘菌素佐剂

PHARMACEUTICALS

IF4.8

2022-06-206

OAAI

New 4-Aminoproline-Based Small Molecule Cyclopeptidomimetics as Potential Modulators of α4β1 Integrin

IF4.6

2021-10-073

OAAI

Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2021-09-162

OA

Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants

PHARMACEUTICALS

IF4.8

2021-02-237

OAAI

Shifting Towards αVβ6Integrin Ligands Using Novel Aminoproline-Based Cyclic Peptidomimetics

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2020-09-218

PREAI

Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate

NEUROBIOLOGY OF DISEASE

IF5.6

2020-05-0125

OAAI

Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2020-02-1318

OAAI

The In Sitico Drug Discovery Toolbox: Applications in Lead Discovery and Optimization

Sitico药物发现工具箱: 在线索发现和优化中的应用

CURRENT MEDICINAL CHEMISTRY

IF3.5

2019-09-1944

PRE

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

IF5

2019-08-0720

OAAI

Unbinding of Translocator Protein 18 kDa (TSPO) Ligands: From in Vitro Residence Time to in Vivo Efficacy via in Silico Simulations

ACS CHEMICAL NEUROSCIENCE

IF3.9

2019-06-2125

OAAI

Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2018-11-287

OAAI

Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases

发现一类新的抗真菌剂，选择性抑制微生物碳酸酐酶

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2018-10-0414

OAAI

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand-based drug design

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2018-09-1717

OAAI

Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2018-02-2615

PREAI

Membrane cholesterol effect on the 5-HT2A receptor: Insights into the lipid-induced modulation of an antipsychotic drug target

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

IF2.7

2017-10-0213

PREAI

Identification of Breast Cancer Inhibitors Specific for G Protein-Coupled Estrogen Receptor (GPER)-Expressing Cells

IF3.4

2017-06-2053

OAAI

Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure Activity Relationships of Benzo[b]thiophene-2carboxamides as Antimalarial Agents

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-02-1448

PREAI

Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2016-08-3119

OAAI

Discovery of New Potential Anti-Infective Compounds Based on Carbonic Anhydrase Inhibitors by Rational Target-Focused Repurposing Approaches

IF3.4

2016-06-1546

PREAI