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Francesca Sanvito

IRCCS San Raffaele Scientific Institute
H指数:48
被引数:9,556

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Oncogenic signalling and host immunocompetency govern senescent cell clearance and systemic inflammation in a mouse model of oncogene-induced senescence

癌基因信号和宿主免疫能力调控癌基因诱导衰老模型中衰老细胞的清除和系统性炎症

2026-10-200
OAAI
Targeting white matter astrocytes with a Gfap-disruptive Cas9 nuclease benefits a murine model of Alexander disease

靶向白质星形胶质细胞,使用Gfap干扰性Cas9核酸酶对亚历山大病小鼠模型有益

2026-09-190
OAAI
Liver-directed lentiviral gene therapy confers durable hepatic and systemic amelioration of methylmalonic acidemia in mice

肝脏靶向的慢病毒基因治疗在小鼠中实现了持久的肝脏和系统性改善甲基丙二酸血症

2026-05-250
OAAI
TIGIT disruption rescues the antitumor activity of low avidity TCR-engineered T cells by increasing TCR signal strength

TIGIT干扰通过增强TCR信号强度,恢复了低亲和力TCR工程化T细胞的抗肿瘤活性。

2026-01-080
OA
Microbiome modulation uncouples efficacy and toxicity induced by immune checkpoint blockade in mouse multiple myeloma

微生物组调控可解耦小鼠多发性骨髓瘤中免疫检查点阻断所诱导的疗效与毒性

2025-11-240
OAAI
CAR19 EngTregs offer broad capacity to modulate immune tolerance and improve safety in B and T cell mediated autoimmune disorders
2025-11-010
PRE
Gene therapy supports long-term reconstitution of patient hematopoietic stem cells in deficiency of adenosine deaminase 2

基因疗法支持腺苷脱氨酶2缺乏症患者造血干细胞的长期重建

2025-10-300
OAAI
Spatiotemporal liver dynamics shape hepatocellular heterogeneity and impact in vivo gene engineering

时空肝脏动力学塑造肝细胞异质性并影响体内基因工程

2025-07-030
OAAI
Cerebral thrombus analysis as a useful diagnostic tool for infective endocarditis in ischemic stroke patients

脑血栓分析可作为缺血性卒中患者感染性心内膜炎的有用诊断工具

2025-02-160
PRE
Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders
2023-05-319
PRE
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models
2022-07-1342
PRE
CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome

从幼稚/干记忆T淋巴细胞制造CAR T细胞可增强抗肿瘤反应,同时减少细胞因子释放综合征

2022-06-15115
OAAI
CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function

基于CRISPR的基因破坏和整合高亲和力的WT1-specific T细胞受体可改善抗肿瘤T细胞功能

2022-02-0928
OA