Fredric P. Manfredsson - Publications, H-index & Citations

Fredric P. Manfredsson

translational neuroscience

41H指数

154论文数

5.5K被引数

收录论文 78

发表时间

Effects of chemogenetic inhibition of serotonergic raphe-striatal neurons on L-DOPA-induced behaviors and neurochemistry in a rat model of Parkinson’s disease 化学遗传抑制血清素能中缝-纹状体神经元对帕金森病大鼠模型中L-DOPA诱导的行为和神经化学的影响

Acta Neuropathologica Communications

IF5.7

2026-03-11

OAAI

Carla N. Budrow; Luis-Daniel Bernal-Conde; Ivette M. Sandoval; Ashley Galfano; Han Grezenko; Angela Velazquez; David J. Marmion; Eden Flores-Barrera; Shruti Venkatesh; Michael Coyle; Kimberly Meyers; Kayla Nguyen; Hannah Holden; Kuei Yuan Tseng; Christopher R. Bishop; Fredric P. Manfredsson

Tau, amyloid-β and α-synuclein co-pathologies synergistically enhance neuroinflammation and hippocampal neuron loss Tau、amyloid-β和α-synuclein共病理性协同增强神经炎症和海马神经元丢失

Neurobiology of Disease

IF5.6

2026-02-24

OAAI

Jhodi M. Webster; Ya-Ting Yang; Aidan T. Miller; Asta Zane; Kasandra Scholz; William J. Stone; Nikhita Mudium; Nicole J. Corbin-Stein; Woong-Jai Won; Anna C. Stoll; Kelsey M. Greathouse; Noelle H. Cooper; Lillian F. Long; Phaedra N. Manuel; Jeremy H. Herskowitz; Talene A. Yacoubian; Daniel J. Tyrrell; Ivette M. Sandoval; Fredric P. Manfredsson; Jeffrey H. Kordower

Gene therapy for Parkinson’s disease—Ample room for optimism 帕金森病的基因治疗——乐观的理由充足

Current Opinion in Neurobiology

IF5.2

2025-12-19

PREAI

Ivette M. Sandoval; Michael F. Salvatore; Fredric P. Manfredsson

Physics of Protein Aggregation in Normal and Accelerated Brain Aging 正常与加速大脑衰老过程中的蛋白质聚集物理学

BioEssays

IF2.7

2025-06-20

OAAI

Alberto J. Espay; Andrea Sturchio; Alberto Imarisio; Emily J. Hill; Brady Williamson; Kora Montemagno; Christian Hoffmann; Hugo Le Roy; Dragomir Milovanovic; Fredric P. Manfredsson

Disease-modifying, multidimensional efficacy of putaminal CaV1.3-shRNA gene therapy in aged parkinsonism male and female macaques Steece-Collier, K.; Caulfield, M.E.; Vander Werp, M.J.; Muller, S.J.; Stancati, J.A.; Chu, Y.; Sandoval, I.M.; Collier, T.J.; Kordower, J.H.; Manfredsson, F.P. 壳核Ca(V)1.3-shRNA基因疗法在老年帕金森综合征雌雄恒河猴中的疾病修饰性、多维度疗效。Mol. Ther. 2025. [Google Scholar] [CrossRef]

Molecular Therapy

IF12

2025-05-27

OAAI

Kathy Steece-Collier; Margaret E. Caulfield; Molly J. Vander Werp; Scott J. Muller; Jennifer A. Stancati; Yaping Chu; Ivette M. Sandoval; Timothy J. Collier; Jeffrey H. Kordower; Fredric P. Manfredsson

Advancing age and sex modulate antidyskinetic efficacy of striatal CaV1.3 gene therapy in a rat model of Parkinson's disease 在帕金森氏病大鼠模型中，年龄和性别的增加调节纹状体CaV1.3基因治疗的抗运动障碍功效

NEUROBIOLOGY OF AGING

IF3.5

2025-05-01

OAAI

Caulfield, Margaret E.; Vander Werp, Molly J.; Stancati, Jennifer A.; Collier, Timothy J.; Sortwell, Caryl E.; Sandoval, Ivette M.; Kordower, Jeffrey H.; Manfredsson, Fredric P.; Steece-Collier, Kathy

The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson's disease (vol 18, 1463941, 2024)

FRONTIERS IN NEURAL CIRCUITS

IF3

2025-04-01

OAAI

Lipari, Natalie; Galfano, Ashley; Venkatesh, Shruti; Grezenko, Han; Sandoval, Ivette M.; Manfredsson, Fredric P.; Bishop, Christopher

Devaluing memories of reward: a case for dopamine

COMMUNICATIONS BIOLOGY

IF5.1

2025-02-03

OAAI

Fry, Benjamin R.; Russell, Nicolette; Fex, Victoria; Mo, Bing; Pence, Nathan; Beatty, Joseph A.; Manfredsson, Fredric P.; Toth, Brandon A.; Burgess, Christian R.; Gershman, Samuel; Johnson, Alexander W.

The α-synuclein seed amplification assay: Interpreting a test of Parkinson's pathology Α-突触核蛋白种子扩增测定: 解释帕金森病病理的测试

PARKINSONISM & RELATED DISORDERS

IF3.4

2025-02-01

PREAI

Espay, Alberto J.; Lees, Andrew J.; Cardoso, Francisco; Frucht, Steven J.; Erskine, Daniel; Sandoval, Ivette M.; Bernal-Conde, Luis Daniel; Sturchio, Andrea; Imarisio, Alberto; Hoffmann, Christian; Montemagno, Kora T.; Milovanovic, Dragomir; Halliday, Glenda M.; Manfredsson, Fredric P.

Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-12-01

OAAI

Sandoval, Ivette M.; Kelley, Christy M.; Bernal-Conde, Luis Daniel; Steece-Collier, Kathy; Marmion, David J.; Davidsson, Marcus; Crosson, Sean M.; Boye, Sanford L.; Boye, Shannon E.; Manfredsson, Fredric P.

The effects of chemogenetic targeting of serotonin-projecting pathways on L-DOPA-induced dyskinesia and psychosis in a bilateral rat model of Parkinson's disease

FRONTIERS IN NEURAL CIRCUITS

IF3

2024-11-14

OAAI

Lipari, Natalie; Galfano, Ashley; Venkatesh, Shruti; Grezenko, Han; Sandoval, Ivette M.; Manfredsson, Fredric P.; Bishop, Christopher

Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-09-27

OAAI

Joers, Valerie; Murray, Benjamin C.; McLaughlin, Caroline; Oliver, Danielle; Staley, Hannah E.; Coronado, Jazmyn; Achat-Mendes, Cindy; Golshani, Sanam; Kelly, Sean D.; Goodson, Matthew; Lee, Danica; Manfredsson, Fredric P.; Moore II, Bob M.; Tansey, Malu Gamez

Advanced Parkinson's disease: A review

PARKINSONISM & RELATED DISORDERS

IF3.4

2024-06-01

PREAI

Aslam, Sana; Manfredsson, Fredric; Stokes, Ashley; Shill, Holly

IFNγ drives neuroinflammation, demyelination, and neurodegeneration in a mouse model of multiple system atrophy Ifn γ 在多系统萎缩的小鼠模型中驱动神经炎症，脱髓鞘和神经变性

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-01-18

OAAI

Corbin-Stein, Nicole J.; Childers, Gabrielle M.; Webster, Jhodi M.; Zane, Asta; Yang, Ya-Ting; Mudium, Nikhita; Gupta, Rajesh; Manfredsson, Fredric P.; Kordower, Jeffrey H.; Harms, Ashley S.

Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

NEUROBIOLOGY OF DISEASE

IF5.6

2023-06-01

OAAI

Caulfield, Margaret E.; Vander Werp, Molly J.; Stancati, Jennifer A.; Collier, Timothy J.; Sortwell, Caryl E.; Sandoval, Ivette M.; Manfredsson, Fredric P.; Steece-Collier, Kathy

Broad Serotonergic Actions of Vortioxetine as a Promising Avenue for the Treatment of L-DOPA-Induced Dyskinesia

CELLS

IF5.2

2023-03-08

OAAI

Budrow, Carla; Elder, Kayla; Coyle, Michael; Centner, Ashley; Lipari, Natalie; Cohen, Sophie; Glinski, John; Kinzonzi, N'Senga; Wheelis, Emily; McManus, Grace; Manfredsson, Fredric; Bishop, Christopher

Characterizing the relationship between L-DOPA-induced-dyskinesia and psychosis-like behaviors in a bilateral rat model of Parkinson's disease

NEUROBIOLOGY OF DISEASE

IF5.6

2023-01-01

OAAI

Lipari, Natalie; Centner, Ashley; Glinski, John; Cohen, Sophie; Manfredsson, Fredric P.; Bishop, Christopher

The multimodal serotonin compound Vilazodone alone, but not combined with the glutamate antagonist Amantadine, reduces L-DOPA-induced dyskinesia in hemiparkinsonian rats

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2022-06-01

PREAI

Cohen, Sophie R.; Terry, Michelle L.; Coyle, Michael; Wheelis, Emily; Centner, Ashley; Smith, Samantha; Glinski, John; Lipari, Natalie; Budrow, Carla; Manfredsson, Fredric P.; Bishop, Christopher

Sequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits

JOURNAL OF PARKINSONS DISEASE

IF5

2022-05-24

OAAI

Negrini, Matilde; Tomasello, Giuseppe; Davidsson, Marcus; Fenyi, Alexis; Adant, Cecile; Hauser, Swantje; Espa, Elena; Gubinelli, Francesco; Manfredsson, Fredric P.; Melki, Ronald; Heuer, Andreas

2021 Workshop: Neurodegenerative Diseases in the Gut-Brain Axis-Parkinson's Disease

GASTROENTEROLOGY

IF25.1

2022-05-01

OAAI

Mawe, Gary M.; Browning, Kirsteen N.; Manfredsson, Fredric P.; Camilleri, Michael; Hamilton, Frank A.; Hollander, Jonathan A.; Sieber, Beth-Anne; Greenwel, Patricia; Shea-Donohue, Terez; Wiley, John W.

研究方向