未登录Structure-Based Discovery of Potent and Selective Small-Molecule α5β1 Integrin Inhibitors for Asthma Therapy基于结构的强效且选择性小分子α5β1整合素抑制剂在哮喘治疗中的发现
Beresis, Richard; Sundaram, Aparna; Jo, Hyunil; Adler, Marc; Wang, Zheng; Mcintosh, Joel; Yeon, Seul Ki; Huang, Qiuya; Ngo, Grace; Sheppard, Dean; Degrado, William F. .png)
分享.png)
收藏分享 收藏 Integrin α2β1 regulates collagen I tethering to modulate hyperresponsiveness in reactive airway disease modelsLiu, Sean; Ngo, Uyen; Tang, Xin-Zi; Ren, Xin; Qiu, Wenli; Huang, Xiaozhu; DeGrado, William; Allen, Christopher D. C.; Jo, Hyunil; Sheppard, Dean; Sundaram, Aparna B. 分享 收藏 分享 收藏 A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesionfibrillin-1中与疾病相关的突变差异调节整合素介导的细胞粘附Del Cid, Joselyn S.; Reed, Nilgun Isik; Molnar, Kathleen; Liu, Sean; Dang, Bobo; Jensen, Sacha A.; DeGrado, William; Handford, Penny A.; Sheppard, Dean; Sundaram, Aparna B. 分享 收藏 IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle ContractilityBulek, Katarzyna; Chen, Xing; Parron, Vandy; Sundaram, Aparna; Herjan, Tomasz; Ouyang, Suidong; Liu, Caini; Majors, Alana; Zepp, Jarod; Gao, Ji; Dongre, Ashok; Bodaszewska-Lubas, Malgorzata; Echard, Arnaud; Aronica, Mark; Carman, Julie; Garantziotis, Stavros; Sheppard, Dean; Li, Xiaoxia 分享 收藏 The incidence of abortion and unintended pregnancy in India, 2015Singh, Susheela; Shekhar, Chander; Acharya, Rajib; Moore, Ann M.; Stillman, Melissa; Pradhan, Manas R.; Frost, Jennifer J.; Sahoo, Harihar; Alagarajan, Manoj; Hussain, Rubina; Sundaram, Aparna; Vlassoff, Michael; Kalyanwala, Shveta; Browne, Alyssa 分享 收藏 分享 收藏 分享 收藏 Targeting integrin a α5β1 ameliorates severe airway hyperresponsiveness in experimental asthmaSundaram, Aparna; Chen, Chun; Khalifeh-Soltani, Amin; Atakilit, Amha; Ren, Xin; Qiu, Wenli; Jo, Hyunil; DeGrado, William; Huang, Xiaozhu; Sheppard, Dean 分享 收藏 IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contractionBhattacharya, Mallar; Sundaram, Aparna; Kudo, Makoto; Farmer, Jessica; Ganesan, Previn; Khalifeh-Soltani, Amin; Arjomandi, Mehrdad; Atabai, Kamran; Huang, Xiaozhu; Sheppard, Dean 分享 收藏 The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinasesKatsumoto, Tamiko R.; Kudo, Makoto; Chen, Chun; Sundaram, Aparna; Callahan, Elliott C.; Zhu, Jing W.; Lin, Joseph; Rosen, Connor E.; Manz, Boryana N.; Lee, Jae W.; Matthay, Michael A.; Huang, Xiaozhu; Sheppard, Dean; Weiss, Arthur 分享 收藏 The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cellsSugimoto, Kotaro; Kudo, Makoto; Sundaram, Aparna; Ren, Xin; Huang, Katherine; Bernstein, Xin; Wang, Yanli; Raymond, Wilfred W.; Erie, David J.; Abrink, Magnus; Caughey, George H.; Huang, Xiaozhu; Sheppard, Dean 分享 收藏 分享 收藏 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
