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R

Rosaria Luciani

University of Modena and Reggio Emilia
H指数:20
被引数:1,165

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The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents

aryl-2-nitroethyl三氨基嘧啶作为抗布氏锥虫剂的发现

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2024-01-013
PRE
Linciano, Pasquale; Pozzi, Cecilia; Tassone, Giusy; Landi, Giacomo; Mangani, Stefano; Santucci, Matteo; Luciani, Rosaria; Ferrari, Stefania; Santarem, Nuno; Tagliazucchi, Lorenzo; Cordeiro-da-Silva, Anabela; Tonelli, Michele; Tondi, Donatella; Bertarini, Laura; Gul, Sheraz; Witt, Gesa; Moraes, Carolina B.; Costantino, Luca; Costi, Maria Paola
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-11-033
OAAI
Linciano, Pasquale; Quotadamo, Antonio; Luciani, Rosaria; Santucci, Matteo; Zorn, Kimberley M.; Foil, Daniel H.; Lane, Thomas R.; da Silva, Anabela Cordeiro; Santarem, Nuno; Moraes, Carolina B.; Freitas-Junior, Lucio; Wittig, Ulrike; Mueller, Wolfgang; Tonelli, Michele; Ferrari, Stefania; Venturelli, Alberto; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Ekins, Sean; Costi, Maria Paola
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth

胸苷酸合酶同型二聚体的去稳定剂加速其蛋白酶体降解并抑制癌症生长

ELIFE
IF0
2022-12-076
OAAI
Costantino, Luca; Ferrari, Stefania; Santucci, Matteo; Salo-Ahen, Outi M. H.; Carosati, Emanuele; Franchini, Silvia; Lauriola, Angela; Pozzi, Cecilia; Trande, Matteo; Gozzi, Gaia; Saxena, Puneet; Cannazza, Giuseppe; Losi, Lorena; Cardinale, Daniela; Venturelli, Alberto; Quotadamo, Antonio; Linciano, Pasquale; Tagliazucchi, Lorenzo; Moschella, Maria Gaetana; Guerrini, Remo; Pacifico, Salvatore; Luciani, Rosaria; Genovese, Filippo; Henrich, Stefan; Alboni, Silvia; Santarem, Nuno; da Silva Cordeiro, Anabela; Giovannetti, Elisa; Peters, Godefridus J.; Pinton, Paolo; Rimessi, Alessandro; Cruciani, Gabriele; Stroud, Robert M.; Wade, Rebecca C.; Mangani, Stefano; Marverti, Gaetano; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1

多目标，选择性化合物设计可产生动质体蝶啶还原酶1的有效抑制剂

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-06-0813
OAAI
Poehner, Ina; Quotadamo, Antonio; Panecka-Hofman, Joanna; Luciani, Rosaria; Santucci, Matteo; Linciano, Pasquale; Landi, Giacomo; Di Pisa, Flavio; Dello Iacono, Lucia; Pozzi, Cecilia; Mangani, Stefano; Gul, Sheraz; Witt, Gesa; Ellinger, Bernhard; Kuzikov, Maria; Santarem, Nuno; Cordeiro-da-Silva, Anabela; Costi, Maria P.; Venturelli, Alberto; Wade, Rebecca C.
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics

通过药物化学，筛选和基因组学的应用，在利什曼原虫中发现苯并噻吩-黄酮醇可阻止米替福新和锑耐药性

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2019-12-0121
PREAI
Borsari, Chiara; Dolores Jimenez-Anton, Maria; Eick, Julia; Bifeld, Eugenia; Jose Torrado, Juan; Isabel Olias-Molero, Ana; Jesus Corral, Maria; Santarem, Nuno; Baptista, Catarina; Severi, Leda; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Linciano, Pasquale; Tait, Annalisa; Costantino, Luca; Luciani, Rosaria; Nevado, Paloma Tejera; Zander-Dinse, Dorothea; Franco, Caio H.; Ferrari, Stefania; Moraes, Carolina B.; Cordeiro-da-Silva, Anabela; Ponterini, Glauco; Clos, Joachim; Maria Alunda, Jose; Paola Costi, Maria
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections

增强苯并噻唑作为蝶啶还原酶-1抑制剂治疗锥虫感染

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-03-2528
OAAI
Linciano, Pasquale; Pozzi, Cecilia; dello Iacono, Lucia; di Pisa, Flavio; Landi, Giacomo; Bonucci, Alessio; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Santarem, Nuno; Baptista, Catarina; Franco, Caio; Moraes, Carolina B.; Mueller, Wolfgang; Wittig, Ulrike; Luciani, Rosaria; Sesenna, Antony; Quotadamo, Antonio; Ferrari, Stefania; Pohner, Ina; Cordeiro-da-Silva, Anabela; Mangani, Stefano; Costantino, Luca; Costi, Maria Paola
SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti-Trypanosoma brucei Agent

作为抗布氏锥虫剂的Chromen-4-one衍生物的SAR研究和生物学特性

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2019-01-297
OAAI
Borsari, Chiara; Santarem, Nuno; Macedo, Sara; Dolores Jimenez-Anton, Maria; Torrado, Juan J.; Isabel Olias-Molero, Ana; Corral, Maria J.; Tait, Annalisa; Ferrari, Stefania; Costantino, Luca; Luciani, Rosaria; Ponterini, Glauco; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Behrens, Birte; Reinshagen, Jeanette; Maria Alunda, Jose; Cordeiro-da-Silva, Anabela; Costi, Maria Paola
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-07-237
OAAI
Saxena, Puneet; Severi, Leda; Santucci, Matteo; Taddia, Laura; Ferrari, Stefania; Luciani, Rosaria; Marverti, Gaetano; Marraccini, Chiara; Tondi, Donatella; Mor, Marco; Scalvini, Laura; Vitiello, Simone; Losi, Lorena; Fonda, Sergio; Pacifico, Salvatore; Guerrini, Remo; D'Arca, Domenico; Ponterini, Glauco; Costi, Maria Paola
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections

用于治疗锥虫感染的芳基硫代氨基脲

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2018-02-0132
OAAI
Linciano, Pasquale; Moraes, Carolina B.; Alcantara, Laura M.; Franco, Caio H.; Pascoalino, Bruno; Freitas-Junior, Lucio H.; Macedo, Sara; Santarem, Nuno; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Ferrari, Stefania; Luciani, Rosaria; Quotadamo, Antonio; Costantino, Luca; Costi, Maria Paola
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

利用2-氨基-1，3，4-噻二唑支架抑制布氏锥虫蝶啶还原酶以支持早期药物发现

ACS OMEGA
IF4.3
2017-09-1129
OAAI
Linciano, Pasquale; Dawson, Alice; Poehner, Ina; Costa, David M.; Sa, Monica S.; Cordeiro-da-Silva, Anabela; Luciani, Rosaria; Gul, Sheraz; Witt, Gesa; Ellinger, Bernhard; Kuzikov, Maria; Gribbon, Philip; Reinshagen, Jeanette; Wolf, Markus; Behrens, Birte; Hannaert, Veronique; Michels, Paul A. M.; Nerini, Erika; Pozzi, Cecilia; di Pisa, Flavio; Landi, Giacomo; Santarem, Nuno; Ferrari, Stefania; Saxena, Puneet; Lazzari, Sandra; Cannazza, Giuseppe; Freitas-Junior, Lucio H.; Moraes, Carolina B.; Pascoalino, Bruno S.; Alcantara, Laura M.; Bertolacini, Claudia P.; Fontana, Vanessa; Wittig, Ulrike; Muller, Wolfgang; Wade, Rebecca C.; Hunter, William N.; Mangani, Stefano; Costantino, Luca; Costi, Maria P.
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

用于开发抗锥虫病药物的黄酮醇衍生物的分析

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2016-08-0542
OAAI
Borsari, Chiara; Luciani, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Dello Iacono, Lucia; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jimenez-Anton, Maria D.; Corral, Maria J.; Ma Alunda, Jose; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola

研究方向

暂未获取到该数据
M
Maria Paola Costi
H 指数:36论文数:378被引数:4,595
S
Stefania Ferrari
H 指数:26论文数:141被引数:2,500
S
Stefano Mangani
H 指数:47论文数:346被引数:7,787
C
Cecilia Pozzi
H 指数:25论文数:126被引数:2,105
A
Anabela Cordeiro‐da‐Silva
H 指数:46论文数:237被引数:2.3万
N
Nuno Santarém
H 指数:27论文数:111被引数:7,616
G
Gaetano Marverti
H 指数:22论文数:116被引数:1,485
M
Matteo Santucci
H 指数:15论文数:49被引数:730
P
Pasquale Linciano
H 指数:22论文数:111被引数:1,969
S
Sheraz Gul
H 指数:25论文数:168被引数:2,055