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Save the mouse! Non-lethal, repeated blood transcriptome profiling in murine disease models Kobzik, Lester; Chenchik, Alex; Hu, Dongfang; Makhanov, Mikhail; Paraiso, Kitt; Ghias, Khadija; Diehl, Paul; Yabaji, Shivraj; Kramnik, Igor 分享 收藏
Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility 脂质过氧化与I型干扰素耦联促进致病性巨噬细胞活化,导致结核病易感性 Yabaji, Shivraj M.; Zhernovkov, Vadim; Araveti, Prasanna Babu; Lata, Suruchi; Rukhlenko, Oleksii S.; Abdullatif, Salam Al; Vanvalkenburg, Arthur; Alekseyev, Yuriy O.; Ma, Qicheng; Dayama, Gargi; Lau, Nelson C.; Johnson, W. Evan; Bishai, William R.; Crossland, Nicholas A.; Campbell, Joshua D.; Kholodenko, Boris N.; Gimelbrant, Alexander A.; Kobzik, Lester; Kramnik, Igor 分享 收藏
Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization 异型肺修复通过不良的巨噬细胞极化促进结核病促进性微环境的形成。 Yabaji, Shivraj M.; Lata, Suruchi; Tseng, Anna E.; Araveti, Prasanna Babu; Lo, Ming; Gavrish, Igor; O'Connell, Aoife K.; Gertje, Hans P.; Belkina, Anna C.; Thurman, Colleen E.; Kiyokawa, Hirofumi; Kotton, Darrell; Tan, Shumin; Endsley, Janice J.; Bishai, William R.; Crossland, Nicholas; Kobzik, Lester; Kramnik, Igor 分享 收藏
Molecular profiles of blood from numerous species that differ in sensitivity to acute inflammation Gregory, David J.; Han, Feifei; Li, Peng; Gritsenko, Marina A.; Kyle, Jennifer; Riley, Frank E.; Chavez, Deborah; Yotova, Vania; Sindeaux, Renata H. M.; Hawash, Mohamed B. F.; Xu, Fengyun; Hung, Li-Yuan; Hayden, Douglas L.; Tompkins, Ronald G.; Lanford, Robert E.; Kobzik, Lester; Hellman, Judith; Jacobs, Jon M.; Barreiro, Luis B.; Xiao, Wenzhong; Warren, H. Shaw 分享 收藏
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N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes Joffre, Jeremie; Wong, Erika; Lawton, Samira; Lloyd, Elliot; Nguyen, Nina; Xu, Fengyun; Sempio, Cristina; Kobzik, Lester; Zlatanova, Ivana; Schumacher, Mark; Klawitter, Jost; Su, Hua; Rabl, Katalin; Wilhelmsen, Kevin; Yeh, Che-Chung; Hellman, Judith 分享 收藏
Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity Inde, Zintis; Croker, Ben A.; Yapp, Clarence; Joshi, Gaurav N.; Spetz, Johan; Fraser, Cameron; Qin, Xingping; Xu, Le; Deskin, Brian; Ghelfi, Elisa; Webb, Gabrielle; Carlin, Aaron F.; Zhu, Yanfang Peipei; Leibel, Sandra L.; Garretson, Aaron F.; Clark, Alex E.; Duran, Jason M.; Pretorius, Victor; Crotty-Alexander, Laura E.; Li, Chendi; Lee, Jamie Casey; Sodhi, Chhinder; Hackam, David J.; Sun, Xin; Hata, Aaron N.; Kobzik, Lester; Miller, Jeffrey; Park, Jin-Ah; Brownfield, Douglas; Jia, Hongpeng; Sarosiek, Kristopher A. 分享 收藏
The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas Bhattacharya, Bidisha; Xiao, Shiqi; Chatterjee, Sujoy; Urbanowski, Michael; Ordonez, Alvaro; Ihms, Elizabeth A.; Agrahari, Garima; Lun, Shichun; Berland, Robert; Pichugin, Alexander; Gao, Yuanwei; Connor, John; Ivanov, Alexander R.; Yan, Bo-Shiun; Kobzik, Lester; Koo, Bang-Bon; Jain, Sanjay; Bishai, William; Kramnik, Igor 分享 收藏
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Activation of CB1R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells and Reduces Acute Inflammation and Organ Injury 激活CB1R促进脂多糖诱导的单核细胞髓源性抑制细胞分泌IL-10,减轻急性炎症和器官损伤 Joffre, Jeremie; Yeh, Che-Chung; Wong, Erika; Thete, Mayuri; Xu, Fengyun; Zlatanova, Ivana; Lloyd, Elliot; Kobzik, Lester; Legrand, Matthieu; Hellman, Judith 分享 收藏