D.D. Leonidas - Publications, H-index & Citations

D.D. Leonidas

University of Thessaly

36H指数

252论文数

4.2K被引数

收录论文 66

发表时间

Structural and Biophysical Characterization of C-Glycosylic 1,2-Thiodisaccharides Reveals Determinants of Selective Binding to Galectin-7 and Galectin-8N C-糖苷键1,2-硫二糖的结构和生物物理表征揭示了与半乳糖凝集素-7和半乳糖凝集素-8N选择性结合的决定因素

ChemMedChem

IF3.4

2026-09-08

OAAI

Anastasia S. Tsagkarakou; Anastassia L. Kantsadi; Vasiliki I. Theodoridou; Nikolaos Veliotis; László Lázár; János József; László Juhász; George Kontopidis; Hakon Leffler; Ulf J. Nilsson; László Somsák; Demetres D. Leonidas

Novel Bio-Functional Electrospun Membranes by Chios Mastic Gum Encapsulation 新型由希俄斯乳香树脂包覆的生物功能化静电纺丝膜

Fibers

IF3.9

2026-03-03

OAAI

Panagiotis Μ. Mastorakis; Sotirios I. Marras; Costas Tsioptsias; Stephanos P. Zaoutsos; Demetres D. Leonidas; Ioannis Tsivintzelis; Anna-Maria G. Psarra

Synthesis and evaluation of tetrahydrobenzo[cd]indole derivatives as glycogen phosphorylase inhibitors 四氢苯并[cd]吲哚衍生物的合成与评价及其作为糖原磷酸化酶抑制剂的评估

MEDICINAL CHEMISTRY RESEARCH

IF3.1

2025-02-08

PREAI

Arunrattiyakorn, Panarat; Juiprasert, Chanitha; Koulas, Symeon M.; Boonsri, Pornthip; Aree, Thammarat; Yagi-Utsumi, Maho; Kato, Koichi; Leonidas, Demetres D.

Evidence for the Quercetin Binding Site of Glycogen Phosphorylase as a Target for Liver-Isoform-Selective Inhibitors against Glioblastoma: Investigation of Flavanols Epigallocatechin Gallate and Epigallocatechin

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2024-10-21

OAAI

Alexopoulos, Serafeim; McGawley, Megan; Mathews, Roshini; Papakostopoulou, Souzana; Koulas, Symeon; Leonidas, Demetres D.; Zwain, Tamara; Hayes, Joseph M.; Skamnaki, Vasiliki

Kinetic and Structural Studies of the Plastidial Solanum tuberosum Phosphorylase

ACS OMEGA

IF4.3

2024-09-25

OAAI

Koulas, Symeon M.; Kyriakis, Efthimios; Tsagkarakou, Anastasia S.; Leonidas, Demetres D.

Biochemical and Structural Studies of LjSK1, a Lotus japonicus GSK3β/SHAGGY-like Kinase, Reveal Its Functional Role

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2024-02-08

PREAI

Solovou, Theodora G. A.; Stravodimos, George; Papadopoulos, Georgios E.; Skamnaki, Vassiliki T.; Papadopoulou, Kalliope; Leonidas, Demetres D.

In Vitro Chondrogenesis Induction by Short Peptides of the Carboxy-Terminal Domain of Transforming Growth Factor β1

BIOMEDICINES

IF3.9

2023-11-29

OAAI

Pitou, Maria; Papachristou, Eleni; Bratsios, Dimitrios; Kefala, Georgia-Maria; Tsagkarakou, Anastasia S.; Leonidas, Demetrios D.; Aggeli, Amalia; Papadopoulos, Georgios E.; Papi, Rigini M.; Choli-Papadopoulou, Theodora

Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3?Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-09-02

PREAI

Lazar, Laszlo; Tsagkarakou, Anastasia S.; Stravodimos, George; Kontopidis, George; Leffler, Hakon; Nilsson, Ulf J.; Somsak, Laszlo; Leonidas, Demetres D.

The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studies

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2023-05-01

OAAI

Liggri, Panagiota G. V.; Tsitsanou, Katerina E.; Stamati, Evgenia C. V.; Saitta, Francesca; Drakou, Christina E.; Leonidas, Demetres D.; Fessas, Dimitrios; Zographos, Spyros E.

Structure activity relationship of the binding of p-coumaroyl glucose to glycogen phosphorylase and its effect on hepatic cell metabolic pathways

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS

IF4.1

2021-12-01

OAAI

Tsagkarakou, Anastasia S.; Chasapi, Styliani A.; Koulas, Symeon M.; Tsialtas, Ioannis; Kyriakis, Efthimios; Drakou, Christina E.; Kun, Sandor; Somsak, Laszlo; Spyroulias, Georgios A.; Psarra, Anna-Maria G.; Leonidas, Demetres D.

Mutagenesis of a Lotus japonicus GSK3β/Shaggy-like kinase reveals functionally conserved regulatory residues

PHYTOCHEMISTRY

IF3.4

2021-06-01

PREAI

Solovou, Theodora G. A.; Garagounis, Constantine; Kyriakis, Efthimios; Bobas, Charalambos; Papadopoulos, Georgios E.; Skamnaki, Vassiliki T.; Papadopoulou, Kalliope K.; Leonidas, Demetres D.

Affinity Crystallography Reveals Binding of Pomegranate Juice Anthocyanins at the Inhibitor Site of Glycogen Phosphorylase: The Contribution of a Sugar Moiety to Potency and Its Implications to the Binding Mode

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2020-08-25

PREAI

Drakou, Christina E.; Gardeli, Chrysavgi; Tsialtas, Ioannis; Alexopoulos, Serafeim; Mallouchos, Athanasios; Koulas, Symeon M.; Tsagkarakou, Anastasia S.; Asimakopoulos, Demetres; Leonidas, Demetres D.; Psarra, Anna-Maria G.; Skamnaki, Vasiliki T.

Editorial: Role of Ribonucleases in Immune Response Regulation During Infection and Cancer

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-02-19

OAAI

Boix, Ester; Acquati, Francesco; Leonidas, Demetres; Pulido, David

The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-D-glucopyranosyl thiazoles, imidazoles and an N-β-D glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-01-01

PREAI

Kyriakis, Efthimios; Karra, Aikaterini G.; Papaioannou, Olga; Solovou, Theodora; Skamnaki, Vassiliki T.; Liggri, Panagiota G. V.; Zographos, Spyros E.; Szennyes, Eszter; Bokor, Eva; Kun, Sandor; Psarra, Anna-Maria G.; Somsak, Laszlo; Leonidas, Demetres D.

Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-06-18

PREAI

Szabo, Katalin E.; Kyriakis, Efthimios; Psarra, Anna-Maria G.; Karra, Aikaterini G.; Sipos, Adam; Docsa, Tibor; Stravodimos, George A.; Katsidou, Elisabeth; Skamnaki, Vassiliki T.; Liggri, Panagiota G. V.; Zographos, Spyros E.; Mandi, Attila; Kiraly, Sandor Balazs; Kurtan, Tibor; Leonidas, Demetres D.; Somsak, Laszlo

High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors

MOLECULES

IF4.6

2019-04-03

OAAI

Fischer, Thomas; Koulas, Symeon M.; Tsagkarakou, Anastasia S.; Kyriakis, Efthimios; Stravodimos, George A.; Skamnaki, Vassiliki T.; Liggri, Panagiota G. V.; Zographos, Spyros E.; Riedl, Rainer; Leonidas, Demetres D.

A multidisciplinary study of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-03-01

OAAI

Kun, Sandor; Begum, Jaida; Kyriakis, Efthimios; Stamati, Evgenia C. V.; Barkas, Thomas A.; Szennyes, Eszter; Bokor, Eva; Szabo, Katalin E.; Stravodimos, George A.; Sipos, Adam; Docsa, Tibor; Gergely, Pal; Moffatt, Colin; Patraskaki, Myrto S.; Kokolaki, Maria C.; Gkerdi, Alkistis; Skamnaki, Vassiliki T.; Leonidas, Demetres D.; Somsak, Laszlo; Hayes, Joseph M.

Evidence for Novel Action at the Cell-Binding Site of Human Angiogenin Revealed by Heteronuclear NMR Spectroscopy, insilico and invivo Studies

CHEMMEDCHEM

IF3.4

2018-01-15

OAAI

Chatzileontiadou, Demetra S. M.; Tsika, Aikaterini C.; Diamantopoulou, Zoi; Delbe, Jean; Badet, Josette; Courty, Jose; Skamnaki, Vassiliki T.; Parmenopoulou, Vanessa; Komiotis, Dimitri; Hayes, Joseph M.; Spyroulias, Georgios A.; Leonidas, Demetres D.

Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-D-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-10-03

PREAI

Bokor, Eva; Kyriakis, Efthimios; Solovou, Theodora G. A.; Koppany, Csenge; Kantsadi, Anastassia L.; Szabo, Katalin E.; Szakacs, Andrea; Stravodimos, George A.; Docsa, Tibor; Skamnaki, Vassiliki T.; Zographos, Spyros E.; Gergely, Pal; Leonidas, Demetres D.; Somsak, Laszlo

Proteomic Analysis of Human Angiogenin Interactions Reveals Cytoplasmic PCNA as a Putative Binding Partner 人类血管生成素相互作用的蛋白质组学分析揭示了细胞质PCNA作为推定的结合伴侣

JOURNAL OF PROTEOME RESEARCH

IF3.6

2017-09-08

PREAI

Chatzileontiadou, Demetra S. M.; Samiotaki, Martina; Alexopoulou, Annika N.; Cotsiki, Marina; Panayotou, George; Stamatiadi, Melina; Balatsos, Nikolaos A. A.; Leonidas, Demetres D.; Kontou, Maria

研究方向