Preparation of Azinones from (Cyclopropylmethoxy)azine EthersJOURNAL OF ORGANIC CHEMISTRYIF3.62023-04-180PRE
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4JOURNAL OF MEDICINAL CHEMISTRYIF6.82022-12-2311PRE
Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic SteatohepatitisJOURNAL OF MEDICINAL CHEMISTRYIF6.82022-11-0214PRE
Structure and Inhibitor Binding Characterization of Oncogenic MLLT1 MutantsACS CHEMICAL BIOLOGYIF3.82021-03-215OA
Sequential Xanthalation and O-Trifluoromethylation of Phenols: A Procedure for the Synthesis of Aryl Trifluoromethyl EthersJOURNAL OF ORGANIC CHEMISTRYIF3.62019-11-1813OAAI
Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic AgentsJOURNAL OF MEDICINAL CHEMISTRYIF6.82018-06-0742PREAI
Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a Treatment for Cardiac FibrosisJOURNAL OF MEDICINAL CHEMISTRYIF6.82018-04-0822PREAI
Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 SynthesisANGEWANDTE CHEMIE-INTERNATIONAL EDITIONIF16.92017-11-2438PREAI
Construction of 1-Heteroary1-3-azabicyclo[3.1.0]hexanes by sp3-sp2 Suzuki-Miyaura and Chan-Evans-Lam Coupling Reactions of Tertiary TrifluoroboratesORGANIC LETTERSIF52017-04-2456PREAI
Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic TreatmentACS MEDICINAL CHEMISTRY LETTERSIF42015-10-0638OAAI
Discovery of Selective Small Molecule Inhibitors of Monoacylglycerol Acyltransferase 3JOURNAL OF MEDICINAL CHEMISTRYIF6.82015-09-0816PREAI
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical CandidateACS MEDICINAL CHEMISTRY LETTERSIF42014-02-2463OAAI
Expedient Synthesis of α-Heteroaryl Piperidines Using a Pd-Catalyzed Suzuki Cross-Coupling-Reduction SequenceORGANIC LETTERSIF52014-01-0320PREAI
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists鉴定四氢吡啶并 [4,3-d] 嘧啶酰胺作为一类新的口服生物可利用的TGR5激动剂ACS MEDICINAL CHEMISTRY LETTERSIF42012-11-0947OA
A New and Useful Method for the Macrocyclization of Linear PeptidesORGANIC LETTERSIF52012-05-2145PREAI
Synthetic modification of manzamine A via Grubbs metathesis. Novel structures with enhanced antibacterial and Antiprotozoal propertiesORGANIC LETTERSIF52007-10-0528OAAI