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M

Miriam A. Giardini

Eberhard Karls University of Tubingen
H指数:14
被引数:912

个人简介

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教育背景

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工作经历

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荣誉奖项

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Identification of Substituted 4-Aminocinnolines as Broad-Spectrum Antiparasitic Agents
ACS INFECTIOUS DISEASES
IF3.8
2025-02-120
OAAI
Spaulding, Andrew; Sharma, Amrita; Giardini, Miriam A.; Hoffman, Benjamin; Bernatchez, Jean A.; Mccall, Laura-Isobel; Calvet, Claudia M.; Ackermann, Jasmin; Souza, Julia M.; Thomas, Diane; Millard, Caroline C.; Devine, William G.; Singh, Baljinder; Silva, Everton M.; Leed, Susan E.; Roncal, Norma E.; Penn, Erica C.; Erath, Jessey; Kumar, Gaurav; Sepulveda, Yadira; Garcia, Arnold; Rodriguez, Ana; El-Sakkary, Nelly; Sciotti, Richard J.; Campbell, Robert F.; Momper, Jeremiah D.; Mckerrow, James H.; Caffrey, Conor R.; Siqueira-Neto, Jair L.; Pollastri, Michael P.; Mensa-Wilmot, Kojo; Ferrins, Lori
Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease

克氏锥虫和布氏组织蛋白酶L样蛋白酶靶向coumarin-3-thiosemicarbazones的纳摩尔活性

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2025-02-010
PRE
Nunes, Jessica Alves; Santos-Junior, Paulo Fernando da Silva; Gomes, Midiane Correa; Ferreira, Luiz Alberto Santos; Padilha, Emanuelly Karla Araujo; Teixeira, Thaiz Rodrigues; Stanger, Emily J.; Kaur, Yashpreet; da Silva, Elany Barbosa; Costa, Clara Andrezza Crisostomo Bezerra; de Freitas, Johnnatan Duarte; De Araujo-Junior, Joao Xavier; Mendonca-Junior, Francisco Jaime Bezerra; Giardini, Miriam A.; Siqueira-Neto, Jair L.; Caffrey, Conor R.; Zhang, Peng; Cardoso, Silvia Helena; da Silva-Junior, Edeildo Ferreira
Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors

氨基硫脲作为SARS-CoV-2主要蛋白酶抑制剂的基于结构的发现

FUTURE MEDICINAL CHEMISTRY
IF3.4
2023-07-125
PRE
Maltarollo, Vinicius Goncalves; da Silva, Elany Barbosa; Kronenberger, Thales; Andrade, Marina Mol Sena; Marques, Gabriel V. de Lima; Oliveira, Nereu J. Candido; Santos, Lucianna H.; Rezende Junior, Celso de Oliveira; Martinho, Ana C. Cassiano; Skinner, Danielle; Fajtova, Pavla; Fernandes, Thais H.; dos Santos, Eduardo da Silveira; Gazolla, Poliana A. Rodrigues; de Souza, Ana P. Martins; da Silva, Milene Lopes; dos Santos, Fabiola S.; Lavorato, Stefania N.; Bretas, Ana C. Oliveira; Carvalho, Diogo Teixeira; Franco, Lucas Lopardi; Luedtke, Stephanie; Giardini, Miriam A.; Poso, Antti; Dias, Luiz C.; Podust, Larissa M.; Alves, Ricardo J.; McKerrow, James; Andrade, Saulo F.; Teixeira, Robson R.; Siqueira-Neto, Jair L.; O'Donoghue, Anthony; de Oliveira, Renata B.; Ferreira, Rafaela S.
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2
JOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
2022-08-1226
OA
Santos, Lucianna H.; Kronenberger, Thales; Almeida, Renata G.; Silva, Elany B.; Rocha, Rafael E. O.; Oliveira, Joyce C.; Barreto, Luiza, V; Skinner, Danielle; Fajtova, Pavla; Giardini, Miriam A.; Woodworth, Brendon; Bardine, Conner; Lourenco, Andre Luiz; Craik, Charles S.; Poso, Antti; Podust, Larissa M.; McKerrow, James H.; Siqueira-Neto, Jair L.; O'Donoghue, Anthony J.; da Silva Junior, Eufranio N.; Ferreira, Rafaela S.
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-07-2124
OAAI
Li, Linfeng; Chenna, Bala C.; Yang, Kai S.; Cole, Taylor R.; Goodall, Zachary T.; Giardini, Miriam; Moghadamchargari, Zahra; Hernandez, Elizabeth A.; Gomez, Jana; Calvet, Claudia M.; Bernatchez, Jean A.; Mellott, Drake M.; Zhu, Jiyun; Rademacher, Andrew; Thomas, Diane; Blankenship, Lauren R.; Drelich, Aleksandra; Laganowsky, Arthur; Tseng, Chien-Te K.; Liu, Wenshe R.; Wand, A. Joshua; Cruz-Reyes, Jorge; Siqueira-Neto, Jair L.; Meek, Thomas D.
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells
ACS CHEMICAL BIOLOGY
IF3.8
2021-03-3182
PREAI
Mellott, Drake M.; Tseng, Chien-Te; Drelich, Aleksandra; Fajtova, Pavla; Chenna, Bala C.; Kostomiris, Demetrios H.; Hsu, Jason; Zhu, Jiyun; Taylor, Zane W.; Kocurek, Klaudia, I; Tat, Vivian; Katzfuss, Ardala; Li, Linfeng; Giardini, Miriam A.; Skinner, Danielle; Hirata, Ken; Yoon, Michael C.; Beck, Sungjun; Carlin, Aaron F.; Clark, Alex E.; Beretta, Laura; Maneval, Daniel; Hook, Vivian; Frueh, Felix; Hurst, Brett L.; Wang, Hong; Raushel, Frank M.; O'Donoghue, Anthony J.; de Siqueira-Neto, Jair Lage; Meek, Thomas D.; McKerrow, James H.
Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
IF3.4
2020-08-019
OAAI
Franco, Caio H.; Warhurst, David C.; Bhattacharyya, Tapan; Au, Ho Y. A.; Le, Hai; Giardini, Miriam A.; Pascoalino, Bruno S.; Torrecilhas, Ana Claudia; Romera, Lavinia M. D.; Madeira, Rafael Pedro; Schenkman, Sergio; Freitas-Junior, Lucio H.; Chatelain, Eric; Miles, Michael A.; Moraes, Carolina B.

研究方向

暂未获取到该数据
J
Jair L. Siqueira-Neto
H 指数:36论文数:183被引数:3,963
E
Elany Barbosa da Silva
H 指数:14论文数:52被引数:696
A
Anthony J. O’Donoghue
H 指数:40论文数:210被引数:5,483
J
James H. McKerrow
H 指数:93论文数:416被引数:2.7万
P
Pavla Fajtová
H 指数:20论文数:66被引数:1,177
D
Danielle Skinner
H 指数:14论文数:42被引数:2,223
J
Jean Bernatchez
H 指数:18论文数:173被引数:1,454
B
Brendon Woodworth
H 指数:7论文数:43被引数:386
A
Aleksandra Drelich
H 指数:23论文数:70被引数:1,784
C
Conor R. Caffrey
H 指数:47论文数:189被引数:8,618