Jair L. Siqueira-Neto

University of California System

H指数:36

被引数:3,963

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工作经历

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荣誉奖项

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Discovery of benzyl carbamate inhibitors of coronavirus Mpro enzymes from a legacy collection of cysteine protease inhibitors

从半胱氨酸蛋白酶抑制剂的馆藏库中发现苯甲氧羰酰基抑制冠状病毒Mpro酶的抑制剂

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2025-12-310

PRE

Sa Magalhaes Serafim, Mateus; Kronenberger, Thales; Francisco, Karol R.; De Sousa Reis, Erik Vinicius; Goncalves De Oliveira, Ellen; Marcelino E Oliveira, Fernanda Kelly; Serraglio Fortes, Isadora; Maciel Fernandes, Thais Helena; Barbosa Da Silva, Elany; Fajtova, Pavla; Skinner, Danielle E.; Syed, Rafay O.; Lage De Siqueira-Neto, Jair; Poso, Antti; Fernandes Mota, Bruno Eduardo; Alves Coelho-dos-Reis, Jordana Grazziela; Santos Abrahao, Jonatas; Goncalves Maltarollo, Vinicius; O'donoghue, Anthony J.; Caffrey, Conor R.

Identification of Substituted 4-Aminocinnolines as Broad-Spectrum Antiparasitic Agents

ACS INFECTIOUS DISEASES

IF3.8

2025-02-120

OAAI

Spaulding, Andrew; Sharma, Amrita; Giardini, Miriam A.; Hoffman, Benjamin; Bernatchez, Jean A.; Mccall, Laura-Isobel; Calvet, Claudia M.; Ackermann, Jasmin; Souza, Julia M.; Thomas, Diane; Millard, Caroline C.; Devine, William G.; Singh, Baljinder; Silva, Everton M.; Leed, Susan E.; Roncal, Norma E.; Penn, Erica C.; Erath, Jessey; Kumar, Gaurav; Sepulveda, Yadira; Garcia, Arnold; Rodriguez, Ana; El-Sakkary, Nelly; Sciotti, Richard J.; Campbell, Robert F.; Momper, Jeremiah D.; Mckerrow, James H.; Caffrey, Conor R.; Siqueira-Neto, Jair L.; Pollastri, Michael P.; Mensa-Wilmot, Kojo; Ferrins, Lori

Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease

克氏锥虫和布氏组织蛋白酶L样蛋白酶靶向coumarin-3-thiosemicarbazones的纳摩尔活性

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-02-010

PRE

Nunes, Jessica Alves; Santos-Junior, Paulo Fernando da Silva; Gomes, Midiane Correa; Ferreira, Luiz Alberto Santos; Padilha, Emanuelly Karla Araujo; Teixeira, Thaiz Rodrigues; Stanger, Emily J.; Kaur, Yashpreet; da Silva, Elany Barbosa; Costa, Clara Andrezza Crisostomo Bezerra; de Freitas, Johnnatan Duarte; De Araujo-Junior, Joao Xavier; Mendonca-Junior, Francisco Jaime Bezerra; Giardini, Miriam A.; Siqueira-Neto, Jair L.; Caffrey, Conor R.; Zhang, Peng; Cardoso, Silvia Helena; da Silva-Junior, Edeildo Ferreira

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (S, Se) and Their Azole Derivatives against Chagas Disease

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-11-010

PRE

Antimalarial drug discovery: progress and approaches (vol 22, pg 807, 2023)

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-09-130

PRE

Oral Pyronaridine Tetraphosphate Reduces Tissue Presence of Parasites in a Mouse Model of Chagas Disease

ACS OMEGA

IF4.3

2024-08-200

OAAI

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

NATURE COMMUNICATIONS

IF15.7

2024-01-312

OAAI

Xie, Stanley C.; Wang, Yinuo; Morton, Craig J.; Metcalfe, Riley D.; Dogovski, Con; Pasaje, Charisse Flerida A.; Dunn, Elyse; Luth, Madeline R.; Kumpornsin, Krittikorn; Istvan, Eva S.; Park, Joon Sung; Fairhurst, Kate J.; Ketprasit, Nutpakal; Yeo, Tomas; Yildirim, Okan; Bhebhe, Mathamsanqa N.; Klug, Dana M.; Rutledge, Peter J.; Godoy, Luiz C.; Dey, Sumanta; De Souza, Mariana Laureano; Siqueira-Neto, Jair L.; Du, Yawei; Puhalovich, Tanya; Amini, Mona; Shami, Gerry; Loesbanluechai, Duangkamon; Nie, Shuai; Williamson, Nicholas; Jana, Gouranga P.; Maity, Bikash C.; Thomson, Patrick; Foley, Thomas; Tan, Derek S.; Niles, Jacquin C.; Han, Byung Woo; Goldberg, Daniel E.; Burrows, Jeremy; Fidock, David A.; Lee, Marcus C. S.; Winzeler, Elizabeth A.; Griffin, Michael D. W.; Todd, Matthew H.; Tilley, Leann

Antimalarial drug discovery: progress and approaches

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2023-08-3150

OAAI

Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors

氨基硫脲作为SARS-CoV-2主要蛋白酶抑制剂的基于结构的发现

FUTURE MEDICINAL CHEMISTRY

IF3.4

2023-07-125

PRE

Maltarollo, Vinicius Goncalves; da Silva, Elany Barbosa; Kronenberger, Thales; Andrade, Marina Mol Sena; Marques, Gabriel V. de Lima; Oliveira, Nereu J. Candido; Santos, Lucianna H.; Rezende Junior, Celso de Oliveira; Martinho, Ana C. Cassiano; Skinner, Danielle; Fajtova, Pavla; Fernandes, Thais H.; dos Santos, Eduardo da Silveira; Gazolla, Poliana A. Rodrigues; de Souza, Ana P. Martins; da Silva, Milene Lopes; dos Santos, Fabiola S.; Lavorato, Stefania N.; Bretas, Ana C. Oliveira; Carvalho, Diogo Teixeira; Franco, Lucas Lopardi; Luedtke, Stephanie; Giardini, Miriam A.; Poso, Antti; Dias, Luiz C.; Podust, Larissa M.; Alves, Ricardo J.; McKerrow, James; Andrade, Saulo F.; Teixeira, Robson R.; Siqueira-Neto, Jair L.; O'Donoghue, Anthony; de Oliveira, Renata B.; Ferreira, Rafaela S.

Enantioselective inhibition of the SARS-CoV-2 main protease with rhenium(i) picolinic acid complexes

CHEMICAL SCIENCE

IF7.4

2023-01-0115

OAAI

A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani

PATHOGENS

IF3.3

2022-11-267

OAAI

Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2022-10-148

Mottin, Melina; Sousa, Bruna Katiele de Paula; Mesquita, Nathalya Cristina de Moraes Roso; de Oliveira, Ketllyn Irene Zagato; Noske, Gabriela Dias; Sartori, Geraldo Rodrigues; Albuquerque, Aline de Oliveira; Urbina, Fabio; Puhl, Ana C.; Moreira-Filho, Jose Teofilo; Souza, Guilherme E.; Guido, Rafael V. C.; Muratov, Eugene; Neves, Bruno Junior; Silva, Joao Herminio Martins; Clark, Alex E.; Siqueira-Neto, Jair L.; Perryman, Alexander L.; Oliva, Glaucius; Ekins, Sean; Andrade, Carolina Horta

Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2022-08-1226