Luke V. Loftus - Publications, H-index & Citations

Luke V. Loftus

johns hopkins

7H指数

32论文数

412被引数

收录论文 10

发表时间

Polyploid cancer cells surviving cisplatin reallocate central carbon sources to fuel antioxidant metabolism for survival 多倍体癌细胞在顺铂处理后重新分配中心碳源以支持抗氧化代谢维持生存

Molecular Metabolism

IF6.6

2026-04-18

OAAI

Melvin Li; Bradley Priem; Luke V. Loftus; Michael J. Betenbaugh; Kenneth J. Pienta; Sarah R. Amend

Polyploid cisplatin-resistant cancer cells have altered nuclear organization and epigenomic status 多倍体顺铂耐药的癌细胞具有改变的核组织和表观基因组状态

Neoplasia

IF7.7

2026-01-21

OAAI

Anna LK Gonye; Linda Orzolek; Christopher Cherry; Michael Patatanian; Luke V Loftus; Kevin Truskowski; George Butler; Kenneth J Pienta; Sarah R Amend

Dysregulation of Labile Iron Predisposes Chemotherapy Resistant Cancer Cells to Ferroptosis 不稳定铁的失调使化疗耐药癌细胞易感于铁死亡

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-04-28

OAAI

Loftus, Luke V.; Rolle, Louis T. A.; Wang, Bowen; Pienta, Kenneth J.; Amend, Sarah R.

Temporal dynamics of ferroptosis vulnerability in a resistant cancer cell state

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Loftus, Luke; Pienta, Ken; Amend, Sarah

Polyploidization enables initial survival of chemotherapy but a progressively increased susceptibility to ferroptosis

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Loftus, Luke

A non-canonical CDK9 complex mediates endocycling in polyaneuploid cancer cell (PACC) state

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Lee, Cheng-Fan; Loycano, Michael; Loftus, Luke; Kostecka, Laurie; Li, Melvin; Amend, Sarah; Pienta, Kenneth

Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex

CELL REPORTS

IF6.9

2021-03-01

OAAI

Mich, John K.; Graybuck, Lucas T.; Hess, Erik E.; Mahoney, Joseph T.; Kojima, Yoshiko; Ding, Yi; Somasundaram, Saroja; Miller, Jeremy A.; Kalmbach, Brian E.; Radaelli, Cristina; Gore, Bryan B.; Weed, Natalie; Omstead, Victoria; Bishaw, Yemeserach; Shapovalova, Nadiya, V; Martinez, Refugio A.; Fong, Olivia; Yao, Shenqin; Mortrud, Marty; Chong, Peter; Loftus, Luke; Bertagnolli, Darren; Goldy, Jeff; Casper, Tamara; Dee, Nick; Opitz-Araya, Ximena; Cetin, Ali; Smith, Kimberly A.; Gwinn, Ryder P.; Cobbs, Charles; Ko, Andrew L.; Ojemann, Jeffrey G.; Keene, C. Dirk; Silbergeld, Daniel L.; Sunkin, Susan M.; Gradinaru, Viviana; Horwitz, Gregory D.; Zeng, Hongkui; Tasic, Bosiljka; Lein, Ed S.; Ting, Jonathan T.; Levi, Boaz P.

Antibody-drug conjugates of NAMPT inhibitors: Discovery, optimization, and preclinical characterization

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Neumann, Chris; Olivas, Kathleen C.; Wang, Kung Pern; Waight, Andrew B.; Meyer, David W.; Loftus, Luke V.; Zaval, Margo C.; Anderson, Martha E.; Jin, Steven; Cochran, Julia H.; Simmons, Jessica K.; Pittman, Paul G.; Li, Fu; Ulrich, Michelle L.; Wong, Abbie; Zeng, Weiping; Lyon, Robert P.; Senter, Peter D.

Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody-Drug Conjugates

MOLECULAR CANCER THERAPEUTICS

IF5.5

2018-12-03

OAAI

Neumann, Christopher S.; Olivas, Kathleen C.; Anderson, Martha E.; Cochran, Julia H.; Jin, Steven; Li, Fu; Loftus, Luke, V; Meyer, David W.; Neale, Jason; Nix, Jay C.; Pittman, Paul G.; Simmons, Jessica K.; Ulrich, Michelle L.; Waight, Andrew B.; Wong, Abbie; Zaval, Margo C.; Zeng, Weiping; Lyon, Robert P.; Senter, Peter D.

Targeted delivery of cytotoxic NAMPT inhibitors using antibody-drug conjugates

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Neumann, Christopher S.; Olivas, Kathleen C.; Waight, Andrew B.; Meyer, David; Loftus, Luke V.; Zaval, Margo; Anderson, Martha E.; Jin, Steven; Cochran, Julia H.; Simmons, Jessica K.; Pittman, Paul G.; Lyon, Robert P.; Senter, Peter D.

研究方向