Mark E. Arnold - Publications, H-index & Citations

Biological Matrix Supply Chain Shortages: More Matrices Are Now Rare-the Case for Surrogate Matrices

IF3.7

2022-05-09

OAAI

Fernandez-Metzler, Carmen; Ackermann, Brad; Garofolo, Fabio; Arnold, Mark E.; DeSilva, Binodh; Gu, Huidong; Laterza, Omar; Mao, Yan; Rose, Mark; Vazvaei-Smith, Faye; Steenwyk, Rick

Overcoming interference with the detection of a stable isotopically labeled microtracer in the evaluation of beclabuvir absolute bioavailability using a concomitant microtracer approach

IF3.7

2022-03-14

OAAI

Dubiel, Evan A.; Myler, Heather; Arnold, Mark E.; Bennett, Patrick; Gatz, Jeff; Groeber, Elizabeth; Gupta, Seema; Kane, Cheikh; Li, Fumin; Mylott, William; Noah, Courtney; O'Dell, Mark; Tewalt, Eric; Warrino, Dominic; Vick, Andrew

Workshop Report: Crystal City VI-Bioanalytical Method Validation for Biomarkers

IF3.1

2017-09-01

PREAI

Jiang, Hao; Titsch, Craig; Zeng, Jianing; Jones, Barry; Joyce, Philip; Gandhi, Yash; Turley, Wesley; Burrell, Richard; Aubry, Anne F.; Arnold, Mark E.

Bioanalysis of dried saliva spot (DSS) samples using detergent-assisted sample extraction with UHPLC-MS/MS detection

IF3.7

2016-08-11

PREAI

Arnold, Mark E.; Booth, Brian; King, Lindsay; Ray, Chad

ANALYTICA CHIMICA ACTA

IF6

2016-08-01

PREAI

Zheng, Naiyu; Zeng, Jianing; Ji, Qin C.; Angeles, Aida; Aubry, Anne-Francoise; Basdeo, Shenita; Buzescu, Adela; Landry, Ishani Savant; Jariwala, Navin; Turley, Wesley; Burrell, Richard; Arnold, Mark E.

Quantitation of a PEGylated protein in monkey serum by UHPLC-HRMS using a surrogate disulfide-containing peptide: A new approach to bioanalysis and in vivo stability evaluation of disulfide-rich protein therapeutics

ANALYTICA CHIMICA ACTA

IF6

2016-04-01

PREAI

Zheng, Naiyu; Zeng, Jianing; Manney, Amy; Williams, Lakenya; Aubry, Anne-Francoise; Voronin, Kimberly; Buzescu, Adela; Zhang, Yan J.; Allentoff, Alban; Xu, Carrie; Shen, Hongwu; Warner, William; Arnold, Mark E.

A highly sensitive and selective LC-MS/MS method to quantify asunaprevir, an HCV NS3 protease inhibitor, in human plasma in support of pharmacokinetic studies

Post-pellet-digestion precipitation and solid phase extraction: A practical and efficient workflow to extract surrogate peptides for ultra-high performance liquid chromatography - tandem mass spectrometry bioanalysis of a therapeutic antibody in the low ng/mL range

IF3.1

2016-02-01

PREAI

Kandoussi, Hamza; Jiang, Hao; Zeng, Jianing; Zheng, Naiyu; Kadiyala, Pathanjali; Eley, Timothy; He, Bing; Garimella, Tushar; Demers, Roger; Cojocaru, Laura; Aubry, Anne-Francoise; Arnold, Mark E.

JOURNAL OF CHROMATOGRAPHY A

IF4

2015-12-01

PREAI

Gong, Chao; Zheng, Naiyu; Zeng, Jianing; Aubry, Anne-Francoise; Arnold, Mark E.

Sensitive and accurate liquid chromatography-tandem mass spectrometry methods for quantitative determination of a novel hepatitis C NS5B inhibitor BMS-791325 and its active metabolite in human plasma and urine

Multiplexed LC-MS/MS method for the simultaneous quantitation of three novel hepatitis C antivirals, daclatasvir, asunaprevir, and beclabuvir in human plasma

IF3.1

2015-03-01

PREAI

Jiang, Hao; Demers, Roger; Kandoussi, Hamza; Burrell, Richard; Eley, Timothy; Kadiyala, Pathanjali; Cojocaru, Laura; Baker, Chanda; Ryan, John; Aubry, Anne-Francoise; Arnold, Mark E.; Zeng, Jianing

Selective Reaction Monitoring of Negative Electrospray Ionization Acetate Adduct Ions for the Bioanalysis of Dapagliflozin in Clinical Studies

IF3.1

2015-03-01

PREAI

Jiang, Hao; Kandoussi, Hamza; Zeng, Jianing; Wang, Jian; Demers, Roger; Eley, Timothy; He, Bing; Burrell, Richard; Easter, John; Kadiyala, Pathanjali; Pursley, Janice; Cojocaru, Laura; Baker, Chanda; Ryan, John; Aubry, Anne-Francoise; Arnold, Mark E.

Workshop Report: Crystal City V-Quantitative Bioanalytical Method Validation and Implementation: The 2013 Revised FDA Guidance

IF6.7

2015-02-24

PREAI

Ji, Qin C.; Xu, Xiaohui; Ma, Eric; Liu, Jane; Basdeo, Shenita; Liu, Guowen; Mylott, William; Boulton, David W.; Shen, Jim X.; Stouffer, Bruce; Aubry, Anne-Francoise; Arnold, Mark E.

Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group

IF3.7

2014-12-31

103

OAAI

Booth, Brian; Arnold, Mark E.; DeSilva, Binodh; Amaravadi, Lakshmi; Dudal, Sherri; Fluhler, Eric; Gorovits, Boris; Haidar, Sam H.; Kadavil, John; Lowes, Steve; Nicholson, Robert; Rock, Marie; Skelly, Michael; Stevenson, Lauren; Subramaniam, Sriram; Weiner, Russell; Woolf, Eric

Introduction to the Proposals from the Global Bioanalysis Consortium Harmonization Team

IF3.7

2014-12-09

OAAI

Evans, Christopher; Arnold, Mark; Bryan, Peter; Duggan, Jeffrey; James, Christopher A.; Li, Wenkui; Lowes, Steve; Matassa, Luca; Olah, Timothy; Timmerman, Philip; Wang, Xiaomin; Wickremsinhe, Enaksha; Williams, John; Woolf, Eric; Zane, Patricia

Selecting the Correct Weighting Factors for Linear and Quadratic Calibration Curves with Least-Squares Regression Algorithm in Bioanalytical LC-MS/MS Assays and Impacts of Using Incorrect Weighting Factors on Curve Stability, Data Quality, and Assay Performance

IF3.7

2014-10-02

OAAI

Timmerman, Philip; Arnold, Mark; DeSilva, Binodh; Garofolo, Fabio; Golob, Michaela; van Amsterdam, Peter; Kudoh, Shinobu; Singhal, Puran; Tang, Daniel; Riccio, Maria Francesca; Barrientos, Rafael; Savale, Shrinivas; Kurokawa, Tatsuo

A Novel and Cost Effective Method of Removing Excess Albumin from Plasma/Serum Samples and Its Impacts on LC-MS/MS Bioanalysis of Therapeutic Proteins

IF6.7

2014-09-04

190

PREAI

Gu, Huidong; Liu, Guowen; Wang, Jian; Aubry, Anne-Francoise; Arnold, Mark E.

Innovative Use of LC-MS/MS for Simultaneous Quantitation of Neutralizing Antibody, Residual Drug, and Human Immunoglobulin G in Immunogenicity Assay Development

IF6.7

2014-08-08

PREAI

Liu, Guowen; Zhao, Yue; Angeles, Aida; Hamuro, Lora L.; Arnold, Mark E.; Shen, Jim X.

Improved liquid-liquid extraction with inter-well volume replacement dilution workflow and its application to quantify BMS-927711 in rat dried blood spots by UHPLC-MS/MS 改进的液-液萃取-孔间体积替代稀释流程及其在uhplc-ms/MS定量大鼠干血斑BMS-927711中的应用

IF6.7

2014-02-17

PREAI

Jiang, Hao; Xu, Weifeng; Titsch, Craig A.; Furlong, Michael T.; Dodge, Robert; Voronin, Kimberly; Allentoff, Alban; Zeng, Jianing; Aubry, Anne-Francoise; DeSilva, Binodh S.; Arnold, Mark E.

Application of a stabilizer cocktail of N-ethylmaleimide and phenylmethanesulfonyl fluoride to concurrently stabilize the disulfide and ester containing compounds in a plasma LC-MS/MS assay

IF3.1

2014-02-01

PREAI

Zheng, Naiyu; Zeng, Jianing; Ji, Qin C.; Angeles, Aida; Buzescu, Adela; Basdeo, Shenita; Aubry, Anne-Francoise; Trouba, Kevin; Patrone, Laura M.; Peng, Qianping; Arnold, Mark E.

Fully Validated LC-MS/MS Assay for the Simultaneous Quantitation of Coadministered Therapeutic Antibodies in Cynomolgus Monkey Serum

IF3.1

2014-01-01

PREAI

Yuan, Long; Jian, Wenying; Zhang, Duxi; Aubry, Anne-Francoise; Arnold, Mark E.