未登录 Interlaboratory validation of the human thyroid microtissue assay 实验室间验证人类甲状腺微组织检测试剂盒 Deisenroth, Chad; Foley, Briana; Rogers, Eda; Kuhnlenz, Julia; Chen, Wei; Feshuk, Madison; Bianchi, Enrica; Mckenna, Josiah; Hill, Bridgett N.; Larocca, Jessica; LeCluyse, Edward L.; Kleinstreuer, Nicole; Thomas, Russell S.; Hogberg, Helena T. 分享 收藏
分享 收藏
Characterization of a human thyroid microtissue model for testing thyroid disrupting chemicals Rogers, E.; Breathwaite, E. K.; Nguyen-Jones, T.; Anderson, S. M.; Odanga, J. J.; Parks, D. T.; Wolf, K. K.; Stone, T.; Balbuena, P.; Chen, J.; Presnell, S. C.; Weaver, J. R.; Lecluyse, E. L. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Hepatocyte-Derived Exosomes Promote Liver Immune Tolerance: Possible Implications for Idiosyncratic Drug-Induced Liver Injury 肝细胞来源的外泌体促进肝脏免疫耐受: 对特异质药物性肝损伤的可能影响 Holman, Natalie S.; Church, Rachel J.; Nautiyal, Manisha; Rose, Kelly A.; Thacker, Sarah E.; Otieno, Monicah A.; Wolf, Kristina K.; LeCluyse, Edward; Watkins, Paul B.; Mosedale, Merrie 分享 收藏
Advancing nonclinical innovation and safety in pharmaceutical testing Baker, Elizabeth J.; Beck, Nancy A.; Berg, Ellen L.; Clayton-Jeter, Helene D.; Chandrasekera, P. Charukeshi; Curley, J. Lowry; Donzanti, Bruce A.; Ewart, Lorna C.; Gunther, Jane M.; Kenna, J. Gerry; LeCluysell, Edward L.; Liebman, Michael N.; Pugh, Catherine L.; Watkins, Paul B.; Sullivan, Kristie M. 分享 收藏
miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model Mosedale, Merrie; Eaddy, J. Scott; Trask, O. Joseph, Jr.; Holman, Natalie S.; Wolf, Kristina K.; LeCluyse, Edward; Ware, Brenton R.; Khetani, Salman R.; Lu, Jingtao; Brock, William J.; Roth, Sharin E.; Watkins, Paul B. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing Wetmore, Barbara A.; Wambaugh, John F.; Allen, Brittany; Ferguson, Stephen S.; Sochaski, Mark A.; Setzer, R. Woodrow; Houck, Keith A.; Strope, Cory L.; Cantwell, Katherine; Judson, Richard S.; LeCluyse, Edward; Clewell, Harvey J.; Thomas, Russell S.; Andersen, Melvin E. 分享 收藏
分享 收藏
Liver biomarker and in vitro assessment confirm the hepatic origin of aminotransferase elevations lacking histopathological correlate in beagle dogs treated with GABAA receptor antagonist NP260 Harrill, Alison H.; Eaddy, John S.; Rose, Kelly; Cullen, John M.; Ramanathan, Lakshmi; Wanaski, Stephen; Collins, Stephen; Ho, Yu; Watkins, Paul B.; LeCluyse, Edward L. 分享 收藏
Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice Harrill, Joshua A.; Hukkanen, Renee R.; Lawson, Marie; Martin, Greg; Gilger, Brian; Soldatow, Valerie; LeCluyse, Edward L.; Budinsky, Robert A.; Rowlands, J. Craig; Thomas, Russell S. 分享 收藏
分享 收藏
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME Godoy, Patricio; Hewitt, Nicola J.; Albrecht, Ute; Andersen, Melvin E.; Ansari, Nariman; Bhattacharya, Sudin; Bode, Johannes Georg; Bolleyn, Jennifer; Borner, Christoph; Boettger, Jan; Braeuning, Albert; Budinsky, Robert A.; Burkhardt, Britta; Cameron, Neil R.; Camussi, Giovanni; Cho, Chong-Su; Choi, Yun-Jaie; Rowlands, J. Craig; Dahmen, Uta; Damm, Georg; Dirsch, Olaf; Teresa Donato, Maria; Dong, Jian; Dooley, Steven; Drasdo, Dirk; Eakins, Rowena; Ferreira, Karine Sa; Fonsato, Valentina; Fraczek, Joanna; Gebhardt, Rolf; Gibson, Andrew; Glanemann, Matthias; Goldring, Chris E. P.; Jose Gomez-Lechon, Maria; Groothuis, Geny M. M.; Gustavsson, Lena; Guyot, Christelle; Hallifax, David; Hammad, Seddik; Hayward, Adam; Haeussinger, Dieter; Hellerbrand, Claus; Hewitt, Philip; Hoehme, Stefan; Holzhuetter, Hermann-Georg; Houston, J. Brian; Hrach, Jens; Ito, Kiyomi; Jaeschke, Hartmut; Keitel, Verena; Kelm, Jens M.; Park, B. Kevin; Kordes, Claus; Kullak-Ublick, Gerd A.; LeCluyse, Edward L.; Lu, Peng; Luebke-Wheeler, Jennifer; Lutz, Anna; Maltman, Daniel J.; Matz-Soja, Madlen; McMullen, Patrick; Merfort, Irmgard; Messner, Simon; Meyer, Christoph; Mwinyi, Jessica; Naisbitt, Dean J.; Nussler, Andreas K.; Olinga, Peter; Pampaloni, Francesco; Pi, Jingbo; Pluta, Linda; Przyborski, Stefan A.; Ramachandran, Anup; Rogiers, Vera; Rowe, Cliff; Schelcher, Celine; Schmich, Kathrin; Schwarz, Michael; Singh, Bijay; Stelzer, Ernst H. K.; Stieger, Bruno; Stoeber, Regina; Sugiyama, Yuichi; Tetta, Ciro; Thasler, Wolfgang E.; Vanhaecke, Tamara; Vinken, Mathieu; Weiss, Thomas S.; Widera, Agata; Woods, Courtney G.; Xu, Jinghai James; Yarborough, Kathy M.; Hengstler, Jan G. 分享 收藏
分享 收藏