田智勇 (Zhiyong Tian)

河南大学教授

H指数:15

被引数:651

个人简介

"田智勇，男，汉族，博士，教授，现为河南大学药学院硕士生导师，主要从事药物化学研究。近5年发表SCIE收录论文7篇，主持省级项目1项，厅级1项。"

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

南阳高质量发展智库专家（2023）｜南阳市委、市政府

Trojan horse tactics: Naphthalimide polyamine conjugates revolutionize cancer treatment

Chemico-Biological Interactions

IF5.4

2026-01-160

PRE

LAMP2-Mediated Autophagy Plasticity Deters Lysosomal Uptake of Platinum Ions to Reverse Cisplatin-Induced Glioma Progression in a Macrophage Dependent Manner

LAMP2介导的自噬可塑性阻止了溶酶体对铂离子的摄取，以巨噬细胞依赖的方式逆转顺铂诱导的胶质瘤进展

Journal of Medicinal Chemistry

IF6.8

2025-07-150

PRE

Naphthalimide-polyamine conjugates: a promising avenue for targeted anticancer therapy

萘二甲酰亚胺-多胺偶联物：靶向抗癌治疗的有前景的途径

European Journal of Medicinal Chemistry Reports

IF4.1

2025-07-100

OAAI

An ortho-activation strategy to develop NIR fluorescent probe for rapid imaging of biothiols in vivo

开发用于体内生物硫醇快速成像的NIR荧光探针的邻位激活策略

TALANTA

IF6.1

2024-01-014

PRE

The substituent group effect: investigation of naphthalimide-spermidine conjugates binding to DNA by spectroscopy, molecular docking and dynamics

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2022-11-012

PRE

Discovery of (S)-N-(3-isopropylphenyl)-2-(5-phenylthiazol-2-yl) pyrrolidine-1-carboxamide as potent and brain-penetrant TRPV1 antagonist

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-04-0112

PRE

Investigation of the interaction of a polyamine-modified flavonoid with bovine serum albumin (BSA) by spectroscopic methods and molecular simulation

光谱法和分子模拟研究多胺修饰的类黄酮与牛血清白蛋白 (BSA) 的相互作用

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

IF3.7

2020-08-0153

PREAI

A Polyamine-Based Dinitro-Naphthalimide Conjugate as Substrates for Polyamine Transporters Preferentially Accumulates in Cancer Cells and Minimizes Side Effects in vitro and in vivo

FRONTIERS IN CHEMISTRY

IF4.2

2020-04-0912

OAAI

Synthesis and biological evaluation of genistein-O-alkylamine derivatives as potential multifunctional anti-Alzheimer agents

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2018-10-218

PREAI

Synthesis and biological evaluation of novel alkylated polyamine analogues as potential anticancer agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-01-0118

OAAI

Study on the interaction of anthracenyl-methyl homospermidine conjugate (ANTMHspd) with DNA by spectroscopic methods

光谱法研究蒽基-甲基高精胺共轭物 (ANTMHspd) 与DNA的相互作用

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

IF3.7

2017-04-018

PREAI

Spectroscopic and molecular modeling methods to study the interaction between naphthalimide-polyamine conjugates and DNA

光谱和分子模拟方法研究萘酰亚胺-多胺缀合物与DNA的相互作用

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

IF3.7

2016-05-0130

PREAI

Spectroscopic Study on the Interaction between Naphthalimide-Polyamine Conjugates and Bovine Serum Albumin (BSA)

MOLECULES

IF4.6

2015-09-1147

OAAI

Spectroscopic study on the interaction between mononaphthalimide spermidine (MINS) and bovine serum albumin (BSA)

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

IF3.7

2015-01-01119

PREAI

Spectroscopic study on the interaction between naphthalimide-polyamine conjugates and DNA

萘酰亚胺-多胺偶联物与DNA相互作用的光谱研究

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

IF3.7

2014-09-0126

PREAI

Study on the Synthesis, Biological Activity and Spectroscopy of Naphthalimide-Diamine Conjugates

MOLECULES

IF4.6

2014-06-1017

OAAI

Reactive oxygen species (ROS) accumulation induced by mononaphthalimide-spermidine leads to intrinsic and AIF-mediated apoptosis in HeLa cells

ONCOLOGY REPORTS

IF3.9

2011-04-0120

OAAI

Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2009-01-0170

PREAI

Synthesis, DNA binding and topoisomerase inhibition of mononaphthalimide homospermidine derivatives

CHINESE CHEMICAL LETTERS

IF8.9

2008-05-018

PREAI

Synthesis and bioevaluation of 5-fluorouracil derivatives

MOLECULES

IF4.6

2007-11-0631

田智勇 (Zhiyong Tian)

个人简介

教育背景

工作经历

荣誉奖项

研究方向