В. С. Броварец - Publications, H-index & Citations

В. С. Броварец

national academy of sciences ukraine

15H指数

433论文数

1.4K被引数

收录论文 26

发表时间

In Vitro Anticancer Activity and In Silico Target Profiling of 5-(Piperazin-1-ylsulfonyl)-1,3-oxazole-4-carbonitriles 5-(哌嗪-1-基磺酰基)-1,3-恶唑-4-甲腈类化合物的体外抗肿瘤活性和计算机靶点分析

International Journal of Molecular Sciences

IF4.9

2026-02-18

PREAI

Severin, Oleksandr O.; Bondar, Denys; Bragina, Olga; Nagappa, Nandish M.; Olev, Janari; Brovarets, Volodymyr S.; Semenyuta, Ivan V.; Karpichev, Yevgen

From flavones to flavanols: An enzymatic kinetic resolution approach to enantioenriched 2-(het)arylchroman-4-ols 从黄酮到黄烷醇：一种酶促动力学拆分制备富集对映异构体的2-（杂）芳基色满-4-醇的方法

Tetrahedron

IF2.2

2026-02-01

PREAI

Timokhin, Oleksii S.; Hys, Vladyslav V.; Kucher, Olexandr V.; Kozytskyi, Andrii V.; Yizhak, Roman V.; Brovarets, Volodymyr S.; Grygorenko, Oleksandr O.; Moskvina, Viktoriia S.

Synthesis and Anticancer Activity Study of New Bis-1,3-Oxazole-5-Sulfonylamides 新型双-1,3-噁唑-5-磺酰胺的合成及抗肿瘤活性研究

ChemMedChem

IF3.4

2025-12-03

PREAI

Maryna Kachaeva; Stepan Pilyo; Diana Hodyna; Yurii Shulha; Volodymyr Brovarets

Synthesis, Anticancer Screening, and Virtual Analysis of 5- S -Substituted Derivatives of 1,3-Oxazol-4-ylphosphonates and 1,3-Oxazole-4-carbonitriles 5- S -取代基衍生物的1,3-恶唑-4-基膦酸酯和1,3-恶唑-4-甲腈的合成、抗癌筛选及虚拟分析

SYNOPEN

IF2.1

2025-12-01

OAAI

Bahrieieva, Oksana S.; Kachaeva, Maryna V.; Kobzar, Oleksandr L.; Shulga, Yurii V.; Golovchenko, Oleksandr V.; Golovchenko, Oksana I.; Nizhenkovska, Iryna V.; Mykhailenko, Oleksandr V.; Pilyo, Stepan G.; Zhirnov, Victor V.; Brovarets, Volodymyr S.

Descriptors of Intermolecular Interaction of π-Conjugated Nitrogen-Containing Heterocycles with Amino Acid Residues of Polypeptides π-共轭含氮杂环与多肽氨基酸残基间分子间相互作用的描述符

THEORETICAL AND EXPERIMENTAL CHEMISTRY

IF0.9

2025-12-01

PREAI

Brovarets, V. S.; Obernikhina, N. V.; Kachkovsky, O. D.

Expanding Chemical Space of N-Acyl Sulfonamides for Carbonic Anhydrase Inhibitor Discovery 扩展N-酰基磺酰胺的化学空间以发现碳酸酐酶抑制剂

European Journal of Medicinal Chemistry

IF5.9

2025-10-23

PREAI

Oleksii V. Gavrylenko; Bohdan V. Vashchenko; Vasyl Naumchyk; Oleksii Chuk; Olga Kuchuk; Alla Pogribna; Anzhelika I. Konovets; Volodymyr S. Brovarets; Sergey A. Zozulya; Dmytro S. Radchenko; Oleksandr O. Grygorenko; Yurii S. Moroz

[3+2] Cycloadditions of α,β-Unsaturated Sultams [3+2] 环加成反应的α,β-不饱和噻吩并吡咯烷酮

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

IF2.7

2025-04-01

PREAI

Zaika, Yevhen O.; Vashchenko, Bohdan V.; Sosunovych, Bohdan S.; Khutorianskyi, Andrii V.; Yasman, Pavlo; Ogurok, Volodymyr M.; Brovarets, Volodymyr S.; Grygorenko, Oleksandr O.

Bridged Bicyclic γ-Sultams by Intramolecular Flow Photochemical [2+2] Cycloaddition

ORGANIC LETTERS

IF5

2025-03-01

PREAI

Zaika, Yevhen O.; Borodin, Illia O.; Olekh, Heorhii O.; Kovalov, Maksym V.; Diachenko, Oleksandr D.; Brovarets, Volodymyr S.; Vashchenko, Bohdan V.; Grygorenko, Oleksandr O.

The molecular features of non-peptidic nucleophilic substrates and acceptor proteins determine the efficiency of sortagging

RSC CHEMICAL BIOLOGY

IF3.1

2025-01-01

OAAI

Bondarchuk, Tetiana; Zhuravel, Elena; Shyshlyk, Oleh; Debelyy, Mykhaylo O.; Pokholenko, Oleksandr; Vaskiv, Diana; Pogribna, Alla; Kuznietsova, Mariana; Hrynyshyn, Yevhenii; Nedialko, Oleksandr; Brovarets, Volodymyr; Zozulya, Sergey A.

Design, Synthesis, and Antitumor Potential of New Thiazole-contained 5-Fluoro-2-Oxindole Derivatives as Sunitinib Analogues

CURRENT MEDICINAL CHEMISTRY

IF3.5

2024-11-04

PREAI

Semenyuta, Ivan; Los, Oleksandr; Sinenko, Vitalii; Zhirnov, Victor; Potikha, Lyudmyla; Kobzar, Oleksandr; Brovarets, Volodymyr

Design, Synthesis, and Xanthine Oxidase Inhibitory Activity of 4-(5-Aminosubstituted-4-cyanooxazol-2-yl)benzoic Acids 4-(5-氨基取代-4-氰基恶唑-2-基) 苯甲酸的设计、合成及黄嘌呤氧化酶抑制活性

CHEMMEDCHEM

IF3.4

2024-09-17

PREAI

Kobzar, Oleksandr; Beiko, Alona; Merzhyievskyi, Danylo; Shablykin, Oleg; Brovarets, Volodymyr; Tanchuk, Vsevolod; Vovk, Andriy

Synthesis, Characterization, In Vitro Anticancer Evaluation, ADMET Properties, and Molecular Docking of Novel 5-Sulfanyl Substituted (Thiazol-4-Yl)-Phosphonium Salts

CHEMMEDCHEM

IF3.4

2024-07-24

PREAI

Semenyuta, Ivan; Golovchenko, Oleksandr; Bahrieieva, Oksana; Vydzhak, Roman; Zhirnov, Victor; Brovarets, Volodymyr

Synthetic Amine Linkers for Efficient Sortagging

BIOCONJUGATE CHEMISTRY

IF3.9

2024-07-12

PREAI

Bondarchuk, Tetiana; Vaskiv, Diana; Zhuravel, Elena; Shyshlyk, Oleh; Hrynyshyn, Yevhenii; Nedialko, Oleksandr; Pokholenko, Oleksandr; Pohribna, Alla; Kuchuk, Olga; Brovarets, Volodymyr; Zozulya, Sergey

Recyclization of 5-Amino- oxazoles as a Route to new Functionalized Heterocycles (Developments of VP Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine)

CHEMICAL RECORD

IF7.5

2023-10-26

PREAI

Shablykin, Oleh V.; Brovarets, Volodymyr S.; Shablykina, Olga V.

Synthesis, Characterization and in vitro Anticancer Evaluation of 5-Sulfinyl(sulfonyl)-4-arylsulfonyl-Substituted 1,3-Oxazoles

CHEMMEDCHEM

IF3.4

2023-05-24

OAAI

Zyabrev, Vladimir; Pilyo, Stepan; Demydchuk, Bohdan; Kachaeva, Maryna; Semenyuta, Ivan; Zhirnov, Victor; Velihina, Yevheniia; Brovarets, Volodymyr

Design, synthesis and evaluation of the anti-breast cancer activity of 1,3-oxazolo[4,5-d]pyrimidine and 1,3-oxazolo[5,4-d]pyrimidine derivatives

RSC MEDICINAL CHEMISTRY

IF3.6

2023-01-01

PREAI

Velihina, Yevheniia; Gesese, Raey; Zhirnov, Victor; Kobzar, Oleksandr; Bui, Benjamin; Pilyo, Stepan; Vovk, Andriy; Shen, Hai-Ying; Brovarets, Volodymyr

Evaluation of Anticancer Activity of 1,3-Oxazol-4-ylphosphonium Salts in Vitro

CHEMMEDCHEM

IF3.4

2022-09-15

OAAI

Brusnakov, Mykhailo; Golovchenko, Olexandr; Velihina, Yevheniia; Liavynets, Oleksandr; Zhirnov, Victor; Brovarets, Volodymyr

Theoretical and Experimental Studies of Phosphonium Ionic Liquids as Potential Antibacterials of MDR Acinetobacter baumannii

ANTIBIOTICS-BASEL

IF4.6

2022-04-06

OAAI

Metelytsia, Larysa O.; Hodyna, Diana M.; Semenyuta, Ivan, V; Kovalishyn, Vasyl V.; Rogalsky, Sergiy P.; Derevianko, Kateryna Yu; Brovarets, Volodymyr S.; Tetko, Igor, V

Carbonic Anhydrase Inhibition with Sulfonamides Incorporating Pyrazole- and Pyridazinecarboxamide Moieties Provides Examples of Isoform-Selective Inhibitors

MOLECULES

IF4.6

2021-11-20

OAAI

Angeli, Andrea; Kartsev, Victor; Petrou, Anthi; Pinteala, Mariana; Brovarets, Volodymyr; Vydzhak, Roman; Panchishin, Svitlana; Geronikaki, Athina; Supuran, Claudiu T.

Design of new imidazole derivatives with anti-HCMV activity: QSAR modeling, synthesis and biological testing

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2021-11-12

PREAI

Kovalishyn, Vasyl; Zyabrev, Volodymyr; Kachaeva, Maryna; Ziabrev, Kostiantyn; Keith, Kathy; Harden, Emma; Hartline, Caroll; James, Scott H.; Brovarets, Volodymyr

研究方向