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G

Giuseppe Manfroni

University of Perugia
H指数:32
被引数:2,493

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2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition

2-苯基喹啉通过非结构蛋白13解旋酶抑制表现出抗严重急性呼吸综合征冠状病毒2活性

ChemMedChem
IF3.4
2026-04-100
OA
Giada Cernicchi; Maria Giulia Nizi; Roberta Emmolo; Leentje Persoons; Manon Laporte; Dirk Jochmans; Isabella Romeo; Giacomo Pepe; Ciro Milite; Pietro Campiglia; Jacopo Spezzini; Alma Martelli; Simone Brogi; Francesca Esposito; Tommaso Felicetti; Serena Massari; Giuseppe Manfroni; Stefano Sabatini; Gianluca Sbardella; Stefano Alcaro; Johan Neyts; Angela Corona; Enzo Tramontano; Steven De Jonghe; Oriana Tabarrini
Sulfonyl Anthranilic Acid Analogues Display Pan-Serotype Anti-Dengue Activity by Downregulating the Expression of Ribosomal Proteins Encoded by 5′-Terminal Oligopyrimidine Motif-Containing mRNA

磺酰基邻氨基苯甲酸类似物通过下调含有5′-端寡聚嘧啶基序的mRNA编码的核糖体蛋白的表达，显示出泛血清型抗登革病毒活性。

Journal of Medicinal Chemistry
IF6.8
2026-03-100
OA
Chin Piaw Gwee; Tommaso Felicetti; Kitti Wing Ki Chan; Min Jie Alvin Tan; Muhammad Danial Bin Mohd Mazlan; Ciro Milite; Giacomo Pepe; Chiara Sarnari; Xiao Dan Ng; Wint Wint Phoo; Jasmine Hwee Yee Tan; Marcus G. Mah; Satoru Watanabe; Jing Xiu Huang; Serena Massari; Oriana Tabarrini; Stefano Sabatini; Pietro Campiglia; Gianluca Sbardella; Gavin J. D. Smith; Sylvie Alonso; Alfred Xuyang Sun; Radoslaw M. Sobota; Subhash G. Vasudevan; Giuseppe Manfroni
Optimization of 2,3-dihydrophthalazine-1,4-dione PARP inhibitor scaffold for nanomolar potency and specificity towards human PARP10

2,3-二氢邻苯并二氮䓬-1,4-二酮PARP抑制剂骨架的优化，以实现纳摩尔级别的效力和对人类PARP10的特异性

European Journal of Medicinal Chemistry
IF5.9
2025-08-300
PREAI
Juho Alaviuhkola; Maria Giulia Nizi; Chiara Vagaggini; Chiara Sarnari; Barbara Lippok; Mirko M. Maksimainen; Chiara Bosetti; Saurabh S. Dhakar; Giuseppe Manfroni; Serena Massari; Elena Dreassi; Patricia Korn; Oriana Tabarrini; Lari Lehtiö
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery

通过调节microRNA加工机制发挥作用的新型抗卵巢癌喹诺酮衍生物

RSC MEDICINAL CHEMISTRY
IF3.6
2025-01-011
OAAI
Felicetti, Tommaso; Di Iacovo, Nicola; Della Fazia, Maria Agnese; Piobbico, Danilo; Pieroni, Stefania; Pacetti, Martina; Yu, Jialing; Sun, Yilun; Massari, Serena; Barreca, Maria Letizia; Sabatini, Stefano; Tabarrini, Oriana; Cecchetti, Violetta; Wang, Fei; Pommier, Yves; Morlando, Mariangela; Servillo, Giuseppe; Manfroni, Giuseppe
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains

新型C-6功能化喹啉诺拉抑制剂与环丙沙星强烈协同对抗浮游和生物膜生长的耐药金黄色葡萄球菌菌株

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2022-11-013
PRE
Felicetti, Tommaso; Cedraro, Nicholas; Astolfi, Andrea; Cernicchi, Giada; Mangiaterra, Gianmarco; Vaiasicca, Salvatore; Massari, Serena; Manfroni, Giuseppe; Barreca, Maria Letizia; Tabarrini, Oriana; Biavasco, Francesca; Cecchetti, Violetta; Vignaroli, Carla; Sabatini, Stefano
Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses

吡啶苯并噻唑酮衍生物HeE1-17Y对包膜RNA病毒的杀病毒活性

VIRUSES-BASEL
IF3.5
2022-05-276
OAAI
Bonotto, Rafaela Milan; Boni, Francesco; Milani, Mario; Chaves-Sanjuan, Antonio; Franze, Silvia; Selmin, Francesca; Felicetti, Tommaso; Bolognesi, Martino; Konstantinidou, Soultana; Poggianella, Monica; Marquez, Chantal L.; Dattola, Federica; Zoppe, Monica; Manfroni, Giuseppe; Mastrangelo, Eloise; Marcello, Alessandro
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti- coronavirus Activity

具有广谱抗冠状病毒活性的2-苯基喹啉类化合物的发现

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2022-05-0315
OA
Nizi, Maria Giulia; Persoons, Leentje; Corona, Angela; Felicetti, Tommaso; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Vangeel, Laura; Barreca, Maria Letizia; Esposito, Francesca; Jochmans, Dirk; Milia, Jessica; Cecchetti, Violetta; Schols, Dominique; Neyts, Johan; Tramontano, Enzo; Sabatini, Stefano; De Jonghe, Steven; Tabarrini, Oriana
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search

通过结合聚焦支架跳跃方法和药效团搜索，从喹啉到基于喹唑啉的金黄色葡萄球菌NorA外排泵抑制剂

CHEMMEDCHEM
IF3.4
2021-06-2612
OAAI
Cedraro, Nicholas; Cannalire, Rolando; Astolfi, Andrea; Mangiaterra, Gianmarco; Felicetti, Tommaso; Vaiasicca, Salvatore; Cernicchi, Giada; Massari, Serena; Manfroni, Giuseppe; Tabarrini, Oriana; Cecchetti, Violetta; Barreca, Maria Letizia; Biavasco, Francesca; Sabatini, Stefano

研究方向

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V
Violetta Cecchetti
H 指数:39论文数:192被引数:4,236
O
Oriana Tabarrini
H 指数:38论文数:177被引数:4,235
S
Stefano Sabatini
H 指数:36论文数:156被引数:5,018
S
Serena Massari
H 指数:30论文数:103被引数:2,226
M
Maria Letizia Barreca
H 指数:38论文数:168被引数:4,309
T
Tommaso Felicetti
H 指数:19论文数:54被引数:906
R
Rolando Cannalire
H 指数:21论文数:50被引数:1,828
A
Andrea Astolfi
H 指数:17论文数:38被引数:629
N
Nunzio Iraci
H 指数:35论文数:102被引数:2,575
C
Christophe Pannecouque
H 指数:71论文数:757被引数:2.0万