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Z

Zhengyin Yan

genentech, 1 dna way, south san francisco, california 98080, united states
H指数:27
被引数:2,502

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Breaking the 1% unbound threshold: an IQ consortium whitepaper on the evaluation of plasma protein binding of highly bound compounds

突破1%游离阈值：IQ联盟关于高度结合化合物血浆蛋白结合评价的白皮书

Drug Metabolism and Disposition
IF4
2026-08-010
PRE
Kazmi, Faraz; Gradhand, Ulrike; Gangl, Eric T.; Fricke, Robert; Aldinger, Tanya; Chambers, Rob; Donzelli, Massimiliano; Ferguson, Douglas; Francq, Bernard G.; Harradine, Paul J.; Kazma, Remi; Mardirosian, Saro; Nicolas, Jean-Marie; Shinkyo, Raku; Simon, Sandrine; Sinz, Michael; Stuart, Patricia; Tatikola, Kanaka; Wittwer, Matthias Beat; Vendrell-Navarro, Gloria; Yan, Zhengyin; Kalvass, John C.
Elucidating Molecular Mechanisms of Drug-Induced Hepatotoxicity of Lapatinib

阐明拉帕替尼药物诱导肝毒性的分子机制

Journal of Medicinal Chemistry
IF6.8
2025-07-250
PRE
Qinying Yu; Li Ma; Leah M. Norona; Peter S. Dragovich; Jianshuang Wang; Shuai Wang; Yi-Chen Chen; S. Cyrus Khojasteh; Jane R. Kenny; Brian J. Dean; Cornelis E. C. A. Hop; Sarah J. Robinson; Ke Sherry Li; Lionel Cheruzel; Aaron Fullerton; Yunxing Cheng; Mingtao He; Xinpeng Wang; Klarissa D. Jackson; Zhengyin Yan; Donglu Zhang
Discovery of GuaB inhibitors with efficacy against Acinetobacter baumannii infection
MBIO
IF4.7
2024-10-163
OAAI
Kofoed, Eric M.; Aliagas, Ignacio; Crawford, Terry; Mao, Jialin; Harris, Seth F.; Xu, Min; Wang, Shumei; Wu, Ping; Ma, Fang; Clark, Kevin; Sims, Jessica; Xu, Yiming; Peng, Yutian; Skippington, Elizabeth; Yang, Ying; Reeder, Janina; Ubhayakar, Savita; Baumgardner, Matt; Yan, Zhengyin; Chen, Jacob; Park, Summer; Zhang, Hua; Yen, Chun-Wan; Lorenzo, Maria; Skelton, Nicholas; Liang, Xiaorong; Chen, Liuxi; Hoag, Bridget; Li, Chun Sing; Liu, Zhiguo; Wai, John; Liu, Xingrong; Liang, Jun; Tan, Man Wah
Industry Perspective on Contemporary Protein-Binding Methodologies: Considerations for Regulatory Drug-Drug Interaction and Related Guidelines on Highly Bound Drugs

对当代蛋白质结合方法的行业观点: 监管药物-药物相互作用的考虑以及高结合药物的相关指南

JOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
2017-12-0183
PREAI
Di, Li; Breen, Christopher; Chambers, Rob; Eckley, Sean T.; Fricke, Robert; Ghosh, Avijit; Harradine, Paul; Kalvass, J. Cory; Ho, Stacy; Lee, Caroline A.; Marathe, Punit; Perkins, Everett J.; Qian, Mark; Tse, Susanna; Yan, Zhengyin; Zamek-Gliszczynski, Maciej J.

研究方向

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C
Cornelis E. C. A. Hop
H 指数:48论文数:249被引数:7,122
J
Jane R. Kenny
H 指数:32论文数:113被引数:2,942
N
Noureddine Maher
H 指数:5论文数:9被引数:259
J
Jingwei Cai
H 指数:33论文数:94被引数:5,724
J
J. Cory Kalvass
H 指数:25论文数:49被引数:2,592
M
Matthew Wright
H 指数:28论文数:154被引数:2,456
D
Donglu Zhang
H 指数:47论文数:233被引数:8,089
Y
Yanming Du
H 指数:23论文数:83被引数:1,532
G
Gary W. Caldwell
H 指数:34论文数:184被引数:3,583
J
Julie Huang
H 指数:4论文数:9被引数:151