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Transporter expressions as part of required scaling factor to support in vitro in vivo extrapolation for blood-brain barrier drug permeability Al-Majdoub, Zubida M.; Cheong, Jonathan; Mizuno, Kunihiko; Hogan, Janita; De Bruyn, Tom; Kanta, Anne; Guo, Jingjing; Hop, Cornelis E. C. A.; Zientek, Mike; Galetin, Aleksandra; Ogungbenro, Kayode; Rostami-Hodjegan, Amin; Barber, Jill 分享 收藏
Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs Zhang, Donglu; Ma, Bin; Dragovich, Peter S.; Ma, Li; Chen, Shu; Chen, Eugene C.; Ye, Xiaofen; Liu, Joyce; Pizzano, Jennifer; Bortolon, Elizabeth; Chan, Emily; Zhang, Xing; Chen, Yi-Chen; Levy, Elizabeth S.; Yauch, Robert L.; Khojasteh, S. Cyrus; Hop, Cornelis E. C. A. 分享 收藏
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Artificial Intelligence for Quantitative Modeling in Drug Discovery and Development: An Innovation and Quality Consortium Perspective on Use Cases and Best Practices Terranova, Nadia; Renard, Didier; Shahin, Mohamed H.; Menon, Sujatha; Cao, Youfang; Hop, Cornelis E. C. A.; Hayes, Sean; Madrasi, Kumpal; Stodtmann, Sven; Tensfeldt, Thomas; Vaddady, Pavan; Ellinwood, Nicholas; Lu, James 分享 收藏
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Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs (vol 64, pg 7045, 2021) Zhang, Donglu; Wei, Cong; Hop, Cornelis E. C. A.; Wright, Matthew R.; Hu, Ming; Lai, Yurong; Khojasteh, S. Cyrus; Humphreys, W. Griff 分享 收藏
Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs Zhang, Donglu; Wei, Cong; Hop, Cornelis E. C. A.; Wright, Matthew R.; Hu, Ming; Lai, Yurong; Khojasteh, S. Cyrus; Humphreys, W. Griff 分享 收藏
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Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper Prasad, Bhagwat; Achour, Brahim; Artursson, Per; Hop, Cornelis E. C. A.; Lai, Yurong; Smith, Philip C.; Barber, Jill; Wisniewski, Jacek R.; Spellman, Daniel; Uchida, Yasuo; Zientek, Michael A.; Unadkat, Jashvant D.; Rostami-Hodjegan, Amin 分享 收藏
Positron Emission Tomography Imaging of [11C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A Billington, Sarah; Shoner, Steven; Lee, Scott; Clark-Snustad, Kindra; Pennington, Matthew; Lewis, David; Muzi, Mark; Rene, Shirley; Lee, Jean; Tot Bui Nguyen; Kumar, Vineet; Ishida, Kazuya; Chen, Laigo; Chu, Xiaoyan; Lai, Yurong; Salphati, Laurent; Hop, Cornelis E. C. A.; Xiao, Guangqing; Liao, Mingxiang; Unadkat, Jashvant D. 分享 收藏
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Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood-Brain Barrier Measured by Quantitative Targeted Proteomics Billington, Sarah; Salphati, Laurent; Hop, Cornelis E. C. A.; Chu, Xiaoyan; Evers, Raymond; Burdette, Doug; Rowbottom, Christopher; Lai, Yurong; Xiao, Guangqing; Humphreys, W. Griffith; Nguyen, Tot Bui; Prasad, Bhagwat; Unadkat, Jashvant D. 分享 收藏
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Strategies of Drug Transporter Quantitation by LC-MS: Importance of Peptide Selection and Digestion Efficiency (vol 19, pg 1469, 2017) Chen, Buyun; Liu, Liling; Ho, Hoangdung; Chen, Yuan; Yang, Ze; Liang, Xiaorong; Payandeh, Jian; Dean, Brian; Hop, Cornelis E. C. A.; Deng, Yuzhong 分享 收藏
Intratumoral Payload Concentration Correlates with the Activity of Antibody-Drug Conjugates Zhang, Donglu; Yu, Shang-Fan; Khojasteh, S. Cyrus; Ma, Yong; Pillow, Thomas H.; Sadowsky, Jack D.; Su, Dian; Kozak, Katherine R.; Xu, Keyang; Polson, Andrew G.; Dragovich, Peter S.; Hop, Cornelis E. C. A. 分享 收藏
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