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I

Ibrahim H. Eissa

al-azhar university

53H指数
233论文数
7.7K被引数
收录论文 105
发表时间
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New Chromene Derivatives as Promising VEGFR-2 Inhibitors: Experimental Cytotoxicity and Comprehensive Computational Characterization新型色满衍生物作为有前景的VEGFR-2抑制剂：实验细胞毒性及全面的计算表征
errArchiv der Pharmazie
IF3.6
err2026-09-10
err0
PREAI
errHazem Elkady; Aisha A. Alsfouk; Eslam B. Elkaeed; Walid E. Elgammal; Hazem A. Mahdy; Ahmed Nofal; Ibrahim H. Eissa; Dalal Z. Husein; Fatma G. Amin; Ahmed M. Metwaly
err分享
err收藏
Identification of Apixaban as a Potential Inhibitor of the SARS-CoV-2 Main Protease: A Multistage Computational Study阿帕曲班作为SARS-CoV-2主蛋白酶潜在抑制剂的鉴定：一项多阶段计算研究
errJournal of Chemistry
IF2.6
err2026-05-26
err0
errOAAI
errAhmed M. Metwaly; Bshra A. Alsfouk; Ibrahim M. Ibrahim; Eslam B. Elkaeed; Ibrahim H. Eissa
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New N-(isoxazol-3-yl)-4-(1,3,4-thiadiazol-3(2H)-yl)benzenesulfonamide derivatives as potent Aurora kinases inhibitors: Design, synthesis and anti-proliferative activity新型N-(异噁唑-3-基)-4-(1,3,4-噻二唑-3(2H)-基)苯磺酰胺衍生物作为强效Aurora激酶抑制剂：设计、合成及抗增殖活性
errBioorganic Chemistry
IF4.7
err2026-05-25
err0
PREAI
errBshra A. Alsfouk; Hazem Elkady; Walid E. Elgammal; Ahmed Nofal; Hazem A. Mahdy; Dalal Z. Husein; Fatma G. Amin; Eslam B. Elkaeed; Ibrahim H. Eissa; Ahmed M. Metwaly
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Structure-Guided Design and Mechanistic Elucidation of New Chromene Derivatives as Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitors With Potent Anticancer Activity基于结构的全新色烯衍生物设计及其作为选择性血管内皮生长因子受体-2抑制剂的抗癌机制阐释
errDrug Development Research
IF4.2
err2026-05-03
err0
PREAI
errHazem Elkady; Walid E. Elgammal; Ibrahim H. Eissa; Hazem A. Mahdy; Aisha A. Alsfouk; Fatma G. Amin; Dalal Z. Husein; Ahmed M. Metwaly; Eslam B. Elkaeed
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Broad-spectrum antiviral potential of vitexin and isovitexin from Jatropha integerrima: in vitro cytoprotective effects and in silico insights长春西汀和异长春西汀来自Jatropha integerrima的广谱抗病毒潜力：体外细胞保护作用和体外模拟研究
errNaunyn-Schmiedeberg's Archives of Pharmacology
IF3.1
err2026-04-02
err0
errOAAI
errHala Sh. Mohammed; Shimaa M. Khalifa; Eman F. S. Taha; Amal H. Ahmed; Ibrahim H. Eissa; Ahmed M. Metwaly; Mohamed Marzouk
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err收藏
Thiadiazole-Derived VEGFR-2 Inhibitors: From Design to Anticancer Evaluation噻二唑衍生的VEGFR-2抑制剂：从设计到抗癌评价
errChemical Biology & Drug Design
IF3.3
err2026-03-26
err0
PREAI
errAlsfouk, Aisha A.; Elkaeed, Eslam B.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Nofal, Ahmed; Eissa, Ibrahim H.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Elkotamy, Mahmoud S.; Metwaly, Ahmed M.
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Aotaphenazine, a rare hydrophenazine, targets topoisomerase II with anticancer efficacy: In silico to in vitro evidenceAotaphenazine，一种罕见的氢化吩噻嗪，靶向拓扑异构酶II并具有抗癌功效：从计算机模拟到体外实验的证据
errPLOS ONE
IF2.6
err2025-12-05
err0
PREAI
errMetwaly, Ahmed M.; Eissa, Ibrahim H.; Afifi, Wael M.; Elkaeed, Eslam B.; Alsfouk, Aisha A.; Ibrahim, Ibrahim M.; Abdelfattah, Mohamed S.
err分享
err收藏
2,3-Dihydro-1,3,4-thiadiazoles as dual B-Raf / VEGFR-2 inhibitors: Design, synthesis, and anti-breast cancer assessment2,3-二氢-1,3,4-噻二唑类化合物作为双B-Raf / VEGFR-2抑制剂的：设计、合成及抗乳腺癌评估
errJournal of Molecular Structure
IF4.7
err2025-11-14
err0
PREAI
errWalid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Alaa Elwan; Dalal Z. Husein; Fatma G. Amin; Bshra A. Alsfouk; Eslam B. Elkaeed; Ibrahim H. Eissa; Ahmed M. Metwaly
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Development of novel furan-based VEGFR-2 inhibitors and apoptotic inducers for colorectal cancer新型呋喃基VEGFR-2抑制剂和促凋亡诱导剂的研发及其在结直肠癌中的应用
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-11-01
err0
PREAI
errElkaeed, Eslam B.; Al Ward, Maged Mohammed Saleh; Elkady, Hazem; Yousef, Reda G.; Elsheshiny, Asmaa A. A.; Abdelfattah, Shimaa. S.; El-Fakharany, Esmail M.; Alsfouk, Aisha A.; Metwaly, Ahmed M.; Eissa, Ibrahim H.
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A novel thiadiazole-based dual inhibitor of carbonic anhydrase-IX and epidermal growth factor receptor targeting cancer: A combined in silico and in vitro approach
errJOURNAL OF CHEMICAL RESEARCH
IF1.2
err2025-11-01
err0
PREAI
errElkaeed, Eslam B.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Al-ghulikah, Hanan A.; Eissa, Ibrahim H.; Metwaly, Ahmed M.
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Design, Computational, Synthesis, and Anti-Cancer Evaluation of a Multifunctional 2,3-Dihydro-1,3,4-Thiadiazole-Benzenesulfonamide Hybrid as a Triple Inhibitor of CAIX, CAXII, and EGFR设计、计算、合成及抗肿瘤评价：一种作为CAIX、CAXII和EGFR三重抑制剂的2,3-二氢-1,3,4-噻二唑-苯磺酰胺类多功能杂化物
errJournal of Computational Biophysics and Chemistry
IF2.3
err2025-11-01
err0
PREAI
errEissa, Ibrahim H.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Abdullah, Rosine; Alsfouk, Aisha A.; Elkaeed, Eslam B.; Metwaly, Ahmed M.
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Integrated Computational and Experimental Discovery of a Promising Xanthine Derivative with Anticancer Potential Targeting EGFR集成计算与实验方法发现一种靶向EGFR且具有抗癌潜力的黄嘌呤衍生物
errCURRENT CANCER DRUG TARGETS
IF3.5
err2025-10-01
err0
PREAI
errElkaeed, Eslam B.; Yousef, Reda G.; Elkady, Hazem; Al-ghulikah, Hanan A.; Ibrahim, Ibrahim M.; Soliman, Omar A.; Husein, Dalal Z.; Doghish, Ahmed S.; Metwaly, Ahmed M.; Eissa, Ibrahim H.
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Exploring the Anticancer Potential of Chitosome-Encapsulated Theobromine Analogue: Integrated Computational, Physiochemical and In vitro Study探索壳聚糖体包封的可可碱类似物的抗癌潜力：整合计算、生理化学和体外研究
errNATURAL PRODUCT COMMUNICATIONS
IF1.4
err2025-10-01
err1
PREAI
errMetwaly, Ahmed M.; Abd-El-Azim, Heba; Zewail, Mariam; Alsfouk, Aisha A.; Elkaeed, Eslam B.; Elkady, Hazem; Eissa, Ibrahim H.
err分享
err收藏
VEGFR-2-Targeted Semisynthetic Theobromine Derivative: A Computer-Aided Drug Design (CADD) Approach
errJournal of Computational Biophysics and Chemistry
IF2.3
err2025-10-01
err0
PREAI
errElkaeed, Eslam B.; Yousef, Reda G.; Elkady, Hazem; Al-ghulikah, Hanan A.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Metwaly, Ahmed M.; Eissa, Ibrahim H.
err分享
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New 1,3,4-Thiadiazole-Based Dual B-Raf/VEGFR-2 Inhibitors With Potential Anti-Breast Activity: Design, Synthesis, In Vitro and In Silico Evaluations新型1,3,4-噻二唑基双B-Raf/VEGFR-2抑制剂及其潜在抗乳腺癌活性：设计、合成、体外及计算机模拟评价
errArchiv der Pharmazie
IF3.6
err2025-09-28
err0
PREAI
errWalid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Bshra A. Alsfouk; Dalal Z. Husein; Fatma G. Amin; Abdelrahman A. Abuelkhir; Eslam B. Elkaeed; Ahmed M. Metwaly; Ibrahim H. Eissa
err分享
err收藏
Development of new thiadiazole-based compounds targeting VEGFR-2: In vitro anticancer evaluation, mechanistic investigations, and in silico studies基于噻二唑的新化合物靶向VEGFR-2的开发：体外抗肿瘤评价、机制研究和计算机模拟研究
errJournal of Molecular Structure
IF4.7
err2025-08-09
err0
PREAI
errBshra A. Alsfouk; Walid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Saber M. Hassan; Dalal Z. Husein; Omar A. Soliman; Mohamed Hagras; Mohamed A. Elkady; Hany G. Ezzat; Ibrahim H. Eissa; Ahmed M. Metwaly; Eslam B. Elkaeed
err分享
err收藏
Integrated computational and biological evaluations of newly synthesized thiadiazole-based VEGFR-2 inhibitors with targeted anti-breast cancer activity综合计算与生物学评价：具有靶向抗乳腺癌活性的新型噻二唑基VEGFR-2抑制剂的合成
errNaunyn-Schmiedeberg's Archives of Pharmacology
IF3.1
err2025-07-23
err0
PREAI
errBshra A. Alsfouk; Walid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Dalal Z. Husein; Omar A. Soliman; Abdelrahman A. Abuelkhir; Ibrahim H. Eissa; Eslam B. Elkaeed; Ahmed M. Metwaly
err分享
err收藏
New Thiadiazole-Benzenesulfonamide Hybrids as Dual B-Raf/VEGFR-2 Inhibitors With Promising Anti-Hepatic Cancer Activity新型噻二唑-苯磺酰胺杂化物作为具有潜在抗肝癌活性的B-Raf/VEGFR-2双重抑制剂
errChemical Biology & Drug Design
IF3.3
err2025-07-20
err0
PREAI
errAisha A. Alsfouk; Hazem Elkady; Saber M. Hassan; Walid E. Elgammal; Hazem A. Mahdy; Dalal Z. Husein; Fatma G. Amin; Mohamed Hagras; Eslam B. Elkaeed; Ahmed M. Metwaly; Ibrahim H. Eissa
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Development of new anticancer thiadiazole-sulfonamides as dual EGFR/carbonic anhydrase inhibitors新型抗癌噻二唑-磺酰胺类化合物的开发作为EGFR/碳酸酐酶双重抑制剂
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-05-08
err0
PREAI
errEissa, Ibrahim H.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Elshennawy, Hany S.; Husein, Dalal Z.; Amin, Fatma G.; Ibrahim, Ibrahim M.; Alsfouk, Bshra A.; Elkaeed, Eslam B.; Metwaly, Ahmed M.
err分享
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Design and synthesis of thiadiazoles as anticancer, apoptotic, and VEGFR-2 inhibitors噻二唑类化合物的设计、合成及其作为抗癌、促凋亡和VEGFR-2抑制剂的活性研究
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-04-08
err0
PREAI
errElgammal, Walid E.; Elkady, Hazem; Dahab, Mohammed A.; Mahdy, Hazem A.; Hagras, Mohamed; Nofal, Ahmed; Alsfouk, Bshra A.; Elkaeed, Eslam B.; Eissa, Ibrahim H.; Metwaly, Ahmed M.
err分享
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