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Krystian Pyta

Adam Mickiewicz University in Poznań

H指数:16

被引数:1,017

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Cascade Mono- and Di-Functionalization of Anticancer Diastereomeric Benzoxazole-Ansamycins toward the Development of Highly Potent Hsp90 Inhibitors of Decreased Toxicity in Normal Cells

抗癌差向异构苯并噁唑-安莎霉素的单-和双-官能化级联反应，用于开发低毒性高活性Hsp90抑制剂

Journal of Medicinal Chemistry

IF6.8

2026-01-010

OA

New Structure Activity Relationship Insight into the Role of the C-3 Extension on Rifamycin Antimycobacterial Activity

新结构-活性关系视角下的C-3延伸对利福霉素抗分枝杆菌活性的作用

IF3.4

2025-09-220

OAAI

Cascade Transformation of the Ansamycin Benzoquinone Core into Benzoxazole Influencing Anticancer Activity and Selectivity

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2023-06-058

OAAI

Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2022-01-248

OAAI

An Approach to Modify 14-Membered Lactone Macrolide Antibiotic Scaffolds

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2022-01-123

OAAI

Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2021-08-0417

OAAI

Synthesis, structure and anticancer activity of new geldanamycin amine analogs containing C(17)- or C(20)- flexible and rigid arms as well as closed or open ansa-bridges

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-09-0111

PREAI

Specific Interactions between Rifamycin Antibiotics and Water Influencing Ability To Overcome Natural Cell Barriers and the Range of Antibacterial Potency

ACS INFECTIOUS DISEASES

IF3.8

2019-08-2813

PREAI

Synthesis, docking and antibacterial studies of more potent amine and hydrazone rifamycin congeners than rifampicin

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-04-0135

PREAI

Solvates of Zwitterionic Rifampicin: Recurring Packing Motifs via Nonspecific Interactions

CRYSTAL GROWTH & DESIGN

IF3.4

2018-01-2513

PREAI

The mechanism of activation of amidobenzylidene ruthenium chelates - latent catalysts of olefin metathesis

DALTON TRANSACTIONS

IF3.3

2017-01-0110

PREAI

Synthesis, Antibacterial, and Anticancer Evaluation of Novel Spiramycin-Like Conjugates Containing C(5) Triazole Arm

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2016-08-1920

PREAI

16-Membered Macrolide Lactone Derivatives Bearing a Triazole-Functionalized Arm at the Aglycone C13 Position as Antibacterial and Anticancer Agents

IF3.4

2016-07-149

PREAI

Structure-activity relationship studies of new rifamycins containing L-amino acid esters as inhibitors of bacterial RNA polymerases

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-06-0112

PREAI

Regio- and Stereoselective Functionalization of 16-Membered Lactone Aglycone of Spiramycin via Cascade Strategy

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2015-07-015

PREAI

Structure and evaluation of antibacterial and antitubercular properties of new basic and heterocyclic 3-formylrifamycin SV derivatives obtained via 'click chemistry' approach

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-09-0133

PREAI

X-ray, spectroscopic and computational studies of the tautomeric structure of a new hydrazone of 5-nitrosalicylaldehyde with indole-3-acetic hydrazide

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2010-04-0133

PREAI

Spectroscopic and theoretical studies of the protonation of N-(5-nitrosalicylidene)-ethylamine

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2010-04-0118

PREAI

Synthesis, crystal structures and antibacterial activity studies of aza-derivatives of phytoalexin from cotton plant - gossypol

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2009-11-0135

PREAI

Structure of a new Schiff base of gossypol with 1-(3-aminopropyl)-2-pyrrolidinone studied by the X-ray, FT-IR, NMR, ESI-MS and PM5 methods

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2008-10-0113

PREAI