Piotr Ruszkowski

Poznan University of Medical Sciences

H指数:17

被引数:919

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Short-Chain Oleanolic Acid Esters and Furoyl Hybrids: Pharmacological Prediction, ADMETox Profiling, In Vitro Cytotoxicity Evaluation, Antioxidant Testing and EGFR Docking

短链齐墩果酸酯和呋喃酰杂化物：药理预测、ADMET毒性分析、体外细胞毒性评价、抗氧化测试和EGFR对接

Pharmaceutics

IF5.5

2026-07-280

Cascade Mono- and Di-Functionalization of Anticancer Diastereomeric Benzoxazole-Ansamycins toward the Development of Highly Potent Hsp90 Inhibitors of Decreased Toxicity in Normal Cells

抗癌差向异构苯并噁唑-安莎霉素的单-和双-官能化级联反应，用于开发低毒性高活性Hsp90抑制剂

Journal of Medicinal Chemistry

IF6.8

2026-01-010

Oleanolic Acid Lactones as Effective Agents in the Combat with Cancers-Cytotoxic and Antioxidant Activity, SAR Analysis, Molecular Docking and ADMETox Profile

齐墩果酸内酯作为抗癌有效药物：细胞毒性及抗氧化活性、构效关系分析、分子对接与ADMET特征

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-04-250

Acetylation of Oleanolic Acid Dimers as a Method of Synthesis of Powerful Cytotoxic Agents

MOLECULES

IF4.6

2024-09-101

OAAI

Acylation of Oleanolic Acid Oximes Effectively Improves Cytotoxic Activity in In Vitro Studies

PHARMACEUTICS

IF5.5

2024-01-092

OAAI

Samarium functionalized few-layer nano graphene oxide redox behavior, cytotoxicity and corrosion inhibition on Mg AZ31 alloy in 3.5% NaCl environment

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2023-12-015

PRE

Modifications of geldanamycin via CuAAC altering affinity to chaperone protein Hsp90 and cytotoxicity

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-08-014

OAAI

Cascade Transformation of the Ansamycin Benzoquinone Core into Benzoxazole Influencing Anticancer Activity and Selectivity

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2023-06-058

OAAI

Biodegradable and Bioactive Carriers Based on Poly(betulin disuccinate-co-sebacic Acid) for Rifampicin Delivery

PHARMACEUTICS

IF5.5

2022-03-069

OAAI

Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2022-01-248

OAAI

Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2021-08-0417

OAAI

Synthesis, structure and anticancer activity of new geldanamycin amine analogs containing C(17)- or C(20)- flexible and rigid arms as well as closed or open ansa-bridges

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-09-0111

PREAI

The influence of cross-linking agent onto adsorption properties, release behavior and cytotoxicity of doxorubicin-imprinted microparticles

COLLOIDS AND SURFACES B-BIOINTERFACES

IF5.6

2019-10-019

PREAI

Application of paclitaxel-imprinted microparticles obtained using two different cross-linkers for prolonged drug delivery

EUROPEAN POLYMER JOURNAL

IF6.3

2019-09-0120

PREAI

Cytotoxic and trypanocidal activities of cinchona alkaloid derivatives

金鸡纳生物碱衍生物的细胞毒性和锥虫杀灭活性

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2018-07-0110

OAAI

Enhancing anticancer activity through the combination of bioreducing agents and triterpenes

FUTURE MEDICINAL CHEMISTRY

IF3.4

2018-02-097

PREAI

Synthesis, Antibacterial, and Anticancer Evaluation of Novel Spiramycin-Like Conjugates Containing C(5) Triazole Arm

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2016-08-1920

PREAI

16-Membered Macrolide Lactone Derivatives Bearing a Triazole-Functionalized Arm at the Aglycone C13 Position as Antibacterial and Anticancer Agents

CHEMMEDCHEM

IF3.4

2016-07-149

PREAI

Biomimetic Multispiked Connecting Ti-Alloy Scaffold Prototype for Entirely-Cementless Resurfacing Arthroplasty Endoprostheses-Exemplary Results of Implantation of the Ca-P Surface-Modified Scaffold Prototypes in Animal Model and Osteoblast Culture Evaluation

MATERIALS

IF3.2

2016-06-2913

OAAI

Synthesis and anticancer activity of some 5-fluoro-2′-deoxyuridine phosphoramidates

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-05-0110

PREAI

Piotr Ruszkowski

个人简介

教育背景

工作经历

荣誉奖项

研究方向