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科言猫学术研究的AI总结
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M

Mohamed A. Helal

egyptian knowledge bank (ekb)

18H指数
61论文数
914被引数
收录论文 27
发表时间
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Molecular docking and experimental validation for the protective effect of betanin against capecitabine-induced myocardial injury: Binding to TLR4 and downregulation of MyD88/NFxB signaling分子对接与实验验证：乙酰硝基蒽醌对卡培他滨诱导的心肌损伤的保护作用：与TLR4结合并下调MyD88/NFxB信号通路
errTISSUE & CELL
IF2.5
err2026-05-23
err0
PREAI
errSaeedi, Tahani A.; Hakem, Fady T.; Helal, Mohamed A.; Mohamed, Marwa Hussein; Khella, Heba W. Z.; Elbassiouny, Mohamed H.; Ismail, Hussein M.; Alshahrani, Asma M.; Mohamed, Abir S.; Saleh, Asmaa; Mohamed, Noura Moustafa; Zaitone, Sawsan A.
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Synthesis, Characterization, and Biological Evaluation of Novel Isatin-Bearing Amino Acid Derivatives: Cytotoxic Activity and Prospective Applications in Medicinal Chemistry新型含异吲哚酮基氨基酸衍生物的合成、表征与生物评价：细胞毒性活性及其在药物化学中的潜在应用
errChemistrySelect
IF2
err2026-01-03
err0
PREAI
errAlhadhrami, Nahlah A.; Al-harbi, Reem A. K.; Alsehli, Amjad H.; Al-ahmadi, Asma M.; Alahmadi, Ghada A.; Aljohani, Wejdan A. S.; Hakem, Fady T.; Helal, Mohamed A.
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The metal ions (Cu(II), Co(II), Ni(II), Mn(II), and UO2(II)) effect on structural, protein binding, in vitro antimicrobial and anticancer potential of quinoline-aminobenzoic acid mixed ligand complexes金属离子（Cu(II)、Co(II)、Ni(II)、Mn(II)和UO2(II)）对喹啉-氨基苯甲酸混合配体配合物的结构、蛋白质结合、体外抗菌和抗癌活性的影响
errJournal of Molecular Structure
IF4.7
err2025-10-13
err0
PREAI
errSh.M. Morgan; M.A. Diab; A.Z. El-Sonbati; M.M. El-Zahed; M.A. El-Mogazy; M.A. Helal; Mahmoud M. Elaasser; H.M. Salama
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Discovery of indole- and quinolone-based inhibitors of the mTOR/Akt/Pi3K pathway for the potential treatment of autism and certain types of cancer发现吲哚和喹诺酮类mTOR/Akt/Pi3K通路抑制剂的潜在治疗自闭症和某些类型癌症的应用
errRSC Med. Chem.
IF3.6
err2025-10-09
err0
PREAI
errAhmad E Elshahary; Hesham Safwan; Ahmad M. Abdelwaly; Reem K. Arafa; Mohamed Helal
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Betanin mitigates vancomycin-induced acute kidney injury in mice and molecular docking indicated inhibition of STAT3 phosphorylation甜菜红素减轻万古霉素诱导的小鼠急性肾损伤，且分子对接表明抑制了STAT3磷酸化。
errTissue and Cell
IF2.5
err2025-09-25
err0
PREAI
errHaifa Alrshedi; Sawsan A. Zaitone; Reem Alshaman; Mohamed A. Helal; Abdullah Alattar; Sarah A. Alshammari; Hibah S. Bedaiwi; Ghiadaa K. Sroor; Ibtisam R. Alnasser; Abduallh J. Ghabban; Eman Serry Zayed; Roba Alatawy; Dina M. Khodeer
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Recent Advances in the Development of Pro-PROTAC for Selective Protein Degradation近期在选择性蛋白质降解的Pro-PROTAC开发方面的最新进展
errPharmaceutics 2025, Vol. 17, Page 1160
IF5.5
err2025-09-04
err0
errOAAI
errFady Hakem; Ahmad Abdelwaly; Reem Alshaman; Abdullah Alattar; Fawaz E. Alanazi; Sawsan A. Zaitone; Mohamed A. Helal
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Development, biological evaluation, and molecular modelling of novel isocytosine and guanidine derivatives as BACE1 inhibitors using a fragment growing strategy
errRSC MEDICINAL CHEMISTRY
IF3.6
err2025-03-01
err0
PREAI
errAtta, Asmaa M.; Rihan, Nouran; Abdelwaly, Ahmad M.; Nafie, Mohamed S.; Elgawish, Mohamed S.; Moustafa, Samia M.; Helal, Mohamed A.; Darwish, Khaled M.
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Molecular Docking, Bioinformatic Analysis, and Experimental Verification for the Effect of Naringin on ADHD: Possible Inhibition of GSK-3β and HSP90
errPHARMACEUTICALS
IF4.8
err2024-10-26
err0
errOAAI
errMokhtar, Hatem I.; Zaitone, Sawsan A.; El-Sayed, Karima; Lashine, Rehab M.; Ahmed, Nada; Moursi, Suzan M. M.; Shehata, Shaimaa A.; Aldahish, Afaf A.; Helal, Mohamed A.; El-Kherbetawy, Mohamed K.; Fawzy, Manal S.; Abd El-Fadeal, Noha M.
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SARS-CoV-2-associated lymphopenia: possible mechanisms and the role of CD147
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2024-07-04
err5
errOAAI
errShouman, Shaimaa; El-Kholy, Nada; Hussien, Alaa E.; El-Derby, Azza M.; Magdy, Shireen; Abou-Shanab, Ahmed M.; Elmehrath, Ahmed O.; Abdelwaly, Ahmad; Helal, Mohamed; El-Badri, Nagwa
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4-Azido-7-nitrobenzoxadiazole as innovative clickable fluorescence probe for trace and selective quantification of ethinylestradiol in human plasma
errLUMINESCENCE
IF3
err2023-08-27
err2
PREAI
errAref, Heba A.; Salama, Ismail; Aboukhatwa, Shaimaa Mohamed; Helal, Mohamed A.; Kishk, Safaa M.; Elgawish, Mohamed Saleh
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Betanin improves motor function and alleviates experimental Parkinsonism via downregulation of TLR4/MyD88/NF-?B pathway: Molecular docking and biological investigations
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2023-08-01
err12
errOAAI
errElSayed, Mohamed H.; Atif, Huda M.; Eladl, Mohamed Ahmed; Elaidy, Samah M.; Helaly, Ahmed M. N.; Hisham, Fatma Azzahraa; Farag, Noha E.; Osman, Noura M. S.; Ibrahiem, Afaf T.; Khella, Heba W. Z.; Bilasy, Shymaa E.; Albalawi, Marzough Aziz; Helal, Mohamed A.; Alzlaiq, Wafa Ali; Zaiton, Sawsan A.
err分享
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Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-09-27
err4
errOAAI
errGalal, Kareem A.; Truong, Anna; Kwarcinski, Frank; de Silva, Chandi; Avalani, Krisha; Havener, Tammy M.; Chirgwin, Michael E.; Merten, Eric; Ong, Han Wee; Willis, Caleb; Abdelwaly, Ahmad; Helal, Mohamed A.; Derbyshire, Emily R.; Zutshi, Reena; Drewry, David H.
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Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands
errCHEMICAL BIOLOGY & DRUG DESIGN
IF3.3
err2022-04-25
err6
PREAI
errElkholy, Nada; Abdelwaly, Ahmad; Mohamed, Karim; Amata, Emanuele; Lombino, Jessica; Cosentino, Giuseppe; Intagliata, Sebastiano; Helal, Mohamed A.
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Discovery of tetrahydro-β-carboline- and indole-based derivatives as promising phosphodiesterase-4 inhibitors: Synthesis, biological evaluation, and molecular modeling studies发现基于四氢-β-咔啉和吲哚的衍生物作为有前途的phosphodiesterase-4抑制剂: 合成，生物学评估和分子模型研究
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2022-01-01
err2
PREAI
errDarwish, Khaled M.; Abdelwaly, Ahmad; Atta, Asmaa M.; Helal, Mohamed A.
err分享
err收藏
Nifuroxazide Mitigates Angiogenesis in Ehlrich's Solid Carcinoma: Molecular Docking, Bioinformatic and Experimental Studies on Inhibition of Il-6/Jak2/Stat3 Signaling
errMOLECULES
IF4.6
err2021-11-13
err14
errOAAI
errEl-Sherbiny, Mohamed; El-Sayed, Rehab M.; Helal, Mohamed A.; Ibrahiem, Afaf T.; Elmahdi, Hoda S.; Eladl, Mohamed Ahmed; Bilay, Shymaa E.; Alshahrani, Asma M.; Tawfik, Mona K.; Hamed, Ziad E.; Mohamed, Amany O.; Zaitone, Sawsan A.
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Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-06-02
err45
errOAAI
errFallica, Antonino N.; Pittala, Valeria; Modica, Maria N.; Salerno, Loredana; Romeo, Giuseppe; Marrazzo, Agostino; Helal, Mohamed A.; Intagliata, Sebastiano
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Interaction of nanoparticles with biological macromolecules: a review of molecular docking studies
errNANOTOXICOLOGY
IF3.4
err2020-12-07
err64
PREAI
errAbdelsattar, Abdallah S.; Dawoud, Alyaa; Helal, Mohamed A.
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Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands
errMOLECULES
IF4.6
err2020-04-17
err2
errOAAI
errIntagliata, Sebastiano; Helal, Mohamed A.; Materia, Luisa; Pittala, Valeria; Salerno, Loredana; Marrazzo, Agostino; Cagnotto, Alfredo; Salmona, Mario; Modica, Maria N.; Romeo, Giuseppe
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Zinc ternary complexes with gabapentin and neurotransmitters: Synthesis, spectral, thermal and molecular docking studies
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2020-01-01
err5
PREAI
errMahmoud, M. A.; Helal, M. A.; Ammar, A. M.
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Development and validation of an HPLC-UV method for simultaneous determination of sildenafil and tramadol in biological fluids: Application to drug-drug interaction study
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2019-05-01
err30
PREAI
errDahshan, Hosam Eldin; Helal, Mohamed A.; Mostafa, Samia M.; Elgawish, Mohamed Saleh
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研究方向

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