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收藏Immunogenicity of avelumab in patients with metastatic Merkel cell carcinoma or advanced urothelial carcinoma
Hu, Ping; Dai, Haiqing Isaac; Bourdage, James; Zhou, Dongli; Trang, Ky; Kowalski, Karey; Bello, Carlo; Hibma, Jennifer; Khandelwal, Akash; Cowan, Kyra; Dong, Jennifer; Venkatakrishnan, Karthik; Gao, Wei
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收藏Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands
van der Plas, Johan L.; Kuiper, Vincent P.; Bagchus, Wilhelmina M.; Boedding, Matthias; Yalkinoglu, Ozkan; Tappert, Aliona; Seitzinger, Andrea; Spangenberg, Thomas; Bezuidenhout, Deon; Wilkins, Justin; Oeuvray, Claude; Dhingra, Satish K.; Thathy, Vandana; Fidock, David A.; Smidt, Lisanne C. A.; Roozen, Geert V. T.; Koopman, Jan Pieter R.; Lamers, Olivia A. C.; Sijtsma, Jeroen; van Schuijlenburg, Roos; Wessels, Els; Meij, Pauline; Kamerling, Ingrid M. C.; Roestenberg, Meta; Khandelwal, Akash
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收藏A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non-small cell lung cancer
Liu, Han; Milenkovic-Grisic, Ana-Marija; Krishnan, Sreenath M.; Joensson, Siv; Friberg, Lena E.; Girard, Pascal; Venkatakrishnan, Karthik; Vugmeyster, Yulia; Khandelwal, Akash; Karlsson, Mats O.
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收藏Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab
Terranova, Nadia; French, Jonathan; Dai, Haiqing; Wiens, Matthew; Khandelwal, Akash; Ruiz-Garcia, Ana; Manitz, Juliane; von Heydebreck, Anja; Ruisi, Mary; Chin, Kevin; Girard, Pascal; Venkatakrishnan, Karthik
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收藏Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab
Grisic, Ana-Marija; Xiong, Wenyuan; Tanneau, Lenaig; Jonsson, Siv; Friberg, Lena E.; Karlsson, Mats O.; Dai, Haiqing; Zheng, Jenny; Girard, Pascal; Khandelwal, Akash
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收藏Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection study
McCarthy, James S.; Yalkinoglu, Ozkan; Odedra, Anand; Webster, Rebecca; Oeuvray, Claude; Tappert, Aliona; Bezuidenhout, Deon; Giddins, Marla J.; Dhingra, Satish K.; Fidock, David A.; Marquart, Louise; Webb, Lachlan; Yin, Xiaoyan; Khandelwal, Akash; Bagchus, Wilhelmina M.
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收藏Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1
Vugmeyster, Yulia; Wilkins, Justin; Koenig, Andre; El Bawab, Samer; Dussault, Isabelle; Ojalvo, Laureen S.; De Banerjee, Samrita; Klopp-Schulze, Lena; Khandelwal, Akash
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收藏Time-Varying Clearance and Impact of Disease State on the Pharmacokinetics of Avelumab in Merkel Cell Carcinoma and Urothelial Carcinoma
Wilkins, Justin J.; Brockhaus, Brigitte; Dai, Haiqing; Vugmeyster, Yulia; White, Joleen T.; Brar, Satjit; Bello, Carlo L.; Neuteboom, Berend; Wade, Janet R.; Girard, Pascal; Khandelwal, Akash
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收藏An open label study introducing post-op tonsillectomy as a new pain model for clinical research in young children
Lefeber, C.; Tarau, E.; Wassmuth, A.; Goldberg, J.; Rosenburg, R.; Sohns, M.; Khandelwal, A.; Muse, D.; Roberts, D.; Gull, J.
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