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Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo de Oca, Rocio Montes; Alavi, Alireza S.; Vitali, Nick; Bhattacharya, Sabyasachi; Blackwell, Christina; Patel, Krupa; Seestaller-Wehr, Laura; Kaczynski, Heather; Shi, Hong; Dobrzynski, Eric; Obert, Leslie; Tsvetkov, Lyuben; Cooper, David C.; Jackson, Heather; Bojczuk, Paul; Forveille, Sabrina; Kepp, Oliver; Sauvat, Allan; Kroemer, Guido; Creighton-Gutteridge, Mark; Yang, Jingsong; Hopson, Chris; Yanamandra, Niranjan; Shelton, Christopher; Mayes, Patrick; Opalinska, Joanna; Barnette, Mary; Srinivasan, Roopa; Smothers, James; Hoos, Axel 分享 收藏
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Immunodynamics of explanted human tumors for immuno-oncology Dubuisson, Agathe; Fahrner, Jean-Eudes; Goubet, Anne-Gaelle; Terrisse, Safae; Voisin, Nicolas; Bayard, Charles; Lofek, Sebastien; Drubay, Damien; Bredel, Delphine; Mouraud, Severine; Susini, Sandrine; Cogdill, Alexandria; Rebuffet, Lucas; Ballot, Elise; Jacquelot, Nicolas; Thomas de Montpreville, Vincent; Casiraghi, Odile; Radulescu, Camelia; Ferlicot, Sophie; Figueroa, David J.; Yadavilli, Sapna; Waight, Jeremy D.; Ballas, Marc; Hoos, Axel; Condamine, Thomas; Parier, Bastien; Gaudillat, Christophe; Routy, Bertrand; Ghiringhelli, Francois; Derosa, Lisa; Breuskin, Ingrid; Rouanne, Mathieu; Andre, Fabrice; Lebacle, Cedric; Baumert, Herve; Wislez, Marie; Fadel, Elie; Cremer, Isabelle; Albiges, Laurence; Geoerger, Birgit; Scoazec, Jean-Yves; Loriot, Yohann; Kroemer, Guido; Marabelle, Aurelien; Bonvalet, Melodie; Zitvogel, Laurence 分享 收藏
Single-agent belantamab mafodotin for relapsed/refractory multiple myeloma: analysis of the lyophilised presentation cohort from the pivotal DREAMM-2 study Richardson, Paul G.; Lee, Hans C.; Abdallah, Al-Ola; Cohen, Adam D.; Kapoor, Prashant; Voorhees, Peter M.; Hoos, Axel; Wang, Karrie; Baron, January; Piontek, Trisha; Byrne, Julie; Richmond, Scott; Jewell, Roxanne C.; Opalinska, Joanna; Gupta, Ira; Lonial, Sagar 分享 收藏
Non-clinical tumor models reveal broad combination potential of ICOS agonist antibodies Waight, Jeremy D.; Bi, Meixia; Kilian, David; Hopson, Christopher; Zhang, Shu-Yun; Brett, Sara; Yadavilli, Sapna; Zhang, Tianqian; Shi, Hong; Hance, Kenneth W.; Ballas, Marc; Hoos, Axel 分享 收藏
Inducible T cell co-stimulatory (ICOS) receptor agonist, GSK3359609 (GSK609) alone and combination with pembrolizumab: Preliminary results from INDUCE-1 expansion cohorts in head and neck squamous cell carcinoma (HNSCC) Le Tourneau, C.; Rischin, D.; Groenland, S.; Lim, A.; Martin-Liberal, J.; Moreno, V.; Trigo, J. M.; Mathew, M.; Cho, D.; Hansen, A.; Baz, D. Vincente; Maio, M.; Italiano, A.; Bauman, J.; Chisamore, M.; Zhou, H.; Ellis, C.; Ballas, M.; Hoos, A.; Angevin, E. 分享 收藏
Pharmacokinetic/pharmacodynamic (PK/PD) exposure-response characterization of GSK3359609 (GSK609) from INDUCE-1, a phase I open-label study Angevin, E.; Groenland, S.; Bauer, T.; Rischin, D.; Gardeazabal, I.; Moreno, V.; Trigo, J. M.; Chisamore, M.; Shaik, J.; Rigat, F.; Ellis, C.; Chen, H.; Gagnon, R.; Scherer, S. J.; Turner, D.; Yadavilli, S.; Ballas, M.; Hoos, A.; Maio, M. 分享 收藏
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A Phase I/II, open-label, two part study of GSK3359609 in combination with tremelimumab in participants with selected, advanced solid tumors Hansen, Aaron; Abdul-Karim, Raghad; Rizvi, Naiyer; Rischen, Danny; Hilton, John; Li, Zujun; Ott, Patrick; Karpinich-Fedoriw, Natalie; Yadavilli, Sapna; Wang, Xiaowei; Adams, Laurel; Wyres, Melody; Ferte, Charles; Ballas, Marc; Hoos, Axel; Zandberg, Daniel 分享 收藏
Antibody-drug conjugate, GSK2857916, in relapsed/refractory multiple myeloma: an update on safety and efficacy from dose expansion phase I study Trudel, Suzanne; Lendvai, Nikoletta; Popat, Rakesh; Voorhees, Peter M.; Reeves, Brandi; Libby, Edward N.; Richardson, Paul G.; Hoos, Axel; Gupta, Ira; Bragulat, Veronique; He, Zangdong; Opalinska, Joanna B.; Cohen, Adam D. 分享 收藏
Preclinical characterization of GSK532, a novel STING agonist with potent anti-tumor activity Yang, Jingsong; Adam, Michael; Clemens, Jim; Creech, Katrina; Schneck, Jess; Pasikanti, Kishore; Jean-Luc Tran; Joglekar, Devika; Hopson, Chris; Pesiridis, Scott; Ramanjulu, Joshi; Lian, Yiqian; Adams, Jerry L.; Smothers, James; Hoos, Axel 分享 收藏
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ICOS agonism induces potent immune activation and anti-tumor response in non-clinical models Yadavilli, Sapna; Zhang, Tianqian; Hahn, Ashleigh; Seestaller-Wehr, Laura M.; Shi, Hong; Liu, Yao-Bin; DeYoung, M. Phillip; Kilian, David J.; Bi, Meixia; Adam, Michael P.; Zhang, Shu-Yun; Bhattacharya, Sabyasachi; Katlinskaya, Yuliya; Blackwell, Christina; Hopson, Christopher B.; Yanamandra, Niranjan; Srinivasan, Roopa; Mayes, Patrick A.; Hoos, Axel 分享 收藏
INDUCE-1: a phase I open-label study of GSK3359609, an ICOS agonist antibody, administered alone and in combination with pembrolizumab in patients with selected, advanced solid tumors Angevin, Eric; Bauer, Todd M.; Ellis, Catherine E.; Gan, Hui; Hall, Rigel; Hansen, Aaron; Hoos, Axel; Jewell, Roxanne C.; Katz, Jessica; Martin-Liberal, Juan; Maio, Michele; Mayes, Patrick A.; Mazumdar, Jolly; Millward, Michael; Rischin, Danny; Schellens, Jan H.; Yadavilli, Sapna; Zhou, Helen 分享 收藏
A phase I, open-label study of GSK3174998 administered alone and in combination with pembrolizumab in patients (pts) with selected advanced solid tumors (ENGAGE-1) Infante, Jeffrey; Ahlers, Christoph M.; Hodi, F. Stephen; Postel-Vinay, Sopie; Schellens, Jan H. M.; Heymach, John V.; Autio, Karen; Barnette, Mary; Struemper, Herbert; Watmuff, Maura; Paul, Elaine M.; Kaufman, David R.; Weber, Jeffrey S.; Hoos, Axel 分享 收藏
Engaging the immune system with GSK3174998, a potent anti-OX40 agonist antibody Toniatti, Carlo; Yanamandra, Niranjan; Voo, Kui; Al-Shami, Amin; Boyer, Laura; Morley, Peter; Brett, Sara; Lofton, Tim; Greer, Jennifer; Feng, Ningping; Wistuba, Ignacio Ivan; Bhattacharya, Sabyasachi; Hopson, Christopher; Kilian, David; Jackson, Heather; Bojczuk, Paul; Mandal, Mili; Jing, Junping; French, Kevin; Srinivasan, Roopa; Hoos, Axel 分享 收藏
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