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J

Jacob E. Corn

University of California

50H指数
164论文数
1.6W被引数
收录论文 64
发表时间
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Chemogenomic maps reveal a PRDX1-dependent iron–damage axis in the DNA damage response化学基因组图谱揭示DNA损伤应答中一个依赖PRDX1的铁-损伤轴
errNature Chemical Biology
IF13.7
err2026-09-08
err0
errOAAI
errThomas A. O’Loughlin; Abolfazl Arab; Sara Misiukiewicz; Elizabeth Montesano; Christopher Yogodzinski; Ashir A. Borah; Valentina Quarantotti; Kevin Lou; Barry S. Rosen; Jacob E. Corn; Davide Gianni; Shaheen Kabir; Josep V. Forment; Luke A. Gilbert
err分享
err收藏
The use of homology-directed repair in a complex landscape of genome editors利用同源定向修复在复杂的基因组编辑景观中的应用
errNature Reviews Molecular Cell Biology
IF90.2
err2026-08-24
err0
PREAI
errEric J. Aird; Jacob E. Corn
err分享
err收藏
RAD51 proximity mapping reveals spatial constraints on homology search during DNA double-stranded break repairRAD51邻近定位揭示了同源搜索在DNA双链断裂修复过程中的空间限制
errCell Reports
IF6.9
err2026-08-17
err0
errOAAI
errCharles D Yeh; Lilly van de Venn; Susanne Kreutzer; Xinhe Zheng; Naomi C. Cantos; Luca V. Bechter; Dominic Mailänder; Markus Schröder; Robin Hofmann; Felix E. Gerbaldo; Alexandra Clemens; Beeke Wienert; Christopher D. Richardson; Zacharias Kontarakis; Jacob E. Corn
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CRISPR in clinical oncology: translational advances from molecular diagnostics to therapeutics临床肿瘤学中的CRISPR: 从分子诊断到治疗的转化进展
errNature Reviews Clinical Oncology
IF82.2
err2026-07-09
err0
PREAI
errSamuel Grigg; Carolyn Shembrey; Mohamed Fareh; Piers Blombery; Jacob E. Corn; John F. Seymour; Joshua M. L. Casan
err分享
err收藏
Polyadenylation of insulin mRNA by Tent5a regulates pancreatic beta cellsTent5a介导的胰岛素mRNA多聚腺苷酸化调控胰腺β细胞
errNature Communications
IF15.7
err2026-05-20
err0
errOAAI
errPamuditha N. Silva; Johanna E. Mayrhofer; Pavlo Potalitsyn; Geraldine O. Trüllinger; Svenja Godbersen; Nic Amstutz; Sebastian M. Siegner; Ben Kodiyan; Alexandra C. Title; Burcak Yesildag; Jacob E. Corn; Marc W. Schmid; Markus Stoffel
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err收藏
ERCC6L2 ensures repair fidelity for staggered-end DNA double-strand breaksERCC6L2 确保错位末端DNA双链断裂的修复保真度
errNature Communications
IF15.7
err2026-02-25
err0
errOAAI
errEric J. Aird; Almudena Serrano-Benitez; Sebastian M. Siegner; Elda Cannavo; Rimma Belotserkovskaya; Nadia Gueorguieva; John Fielden; Grégoire Cullot; Sandra Ammann; Aldo S. Bader; Vipul Gupta; Geoffroy Andrieux; Rebecca Raab; Mónica Del Rey González; Toni Cathomen; Petr Cejka; Jacob E. Corn; Stephen P. Jackson
err分享
err收藏
A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles一种裂分位点E3连接酶机制使ZNFX1能够泛素化并聚集单链RNA，形成泛素包被的核蛋白颗粒。
errCell
IF42.5
err2025-08-27
err0
errOAAI
errDaniel B. Grabarczyk; Eric J. Aird; Vanessa Reznikow; Paul C. Kirchgatterer; Julian F. Ehrmann; Robert Kurzbauer; Lillie E. Bell; Max J. Kellner; Ritika Aggarwal; Alexander Schleiffer; Victoria Faas; Luiza Deszcz; Anton Meinhart; Gijs A. Versteeg; Josef M. Penninger; Lukas S. Stelzl; Moritz M. Gaidt; Ingrid Tessmer; Jacob E. Corn; Tim Clausen
err分享
err收藏
Treatment of GATA2 deficiency by allele-specific CRISPR/Cas9-directed gene correction in hematopoietic stem cells通过等位基因特异性CRISPR/Cas9介导的基因修复治疗GATA2缺陷在造血干细胞中的应用
errMolecular Therapy
IF12
err2025-07-29
err0
PREAI
errThomas Wisbech Skov; Jonas Holst Wolff; Didde Haslund; Anne Louise Revenfeld; Lilly van de Venn; Sofie Rahbek Dorset; Sujan Ravendran; Sofie Eg Jørgensen; Martin Kristian Thomsen; Mette Holm; Jacob E. Corn; Bjarne Kuno Møller; Trine H. Mogensen; Rasmus O. Bak; Jacob Giehm Mikkelsen
err分享
err收藏
Single-stranded HDR templates with truncated Cas12a-binding sequences improve knock-in efficiencies in primary human T cells含截短Cas12a结合序列的单链HDR模板可提高原代人T细胞的敲入效率
errMolecular Therapy Nucleic Acids
IF6.1
err2025-05-19
err0
errOAAI
errAna-Maria Nitulescu; Weijie Du; Viktor Glaser; Jonas Kath; Eric J. Aird; Grégoire Cullot; Robert Greensmith; Nanna Steengaard Mikkelsen; Maik Stein; Rasmus O. Bak; Michael Kaminski; Jacob E. Corn; Dimitrios L. Wagner
err分享
err收藏
Genome editing with the HDR-enhancing DNA-PKcs inhibitor AZD7648 causes large-scale genomic alterations使用增强HDR的dna-pkcs抑制剂AZD7648进行基因组编辑会导致大规模的基因组改变
errNATURE BIOTECHNOLOGY
IF41.7
err2024-11-27
err0
errOAAI
errCullot, Gregoire; Aird, Eric J.; Schlapansky, Moritz F.; Yeh, Charles D.; van de Venn, Lilly; Vykhlyantseva, Iryna; Kreutzer, Susanne; Mailaender, Dominic; Lewkow, Bohdan; Klermund, Julia; Montellese, Christian; Biserni, Martina; Aeschimann, Florian; Vonarburg, Cedric; Gehart, Helmuth; Cathomen, Toni; Corn, Jacob E.
err分享
err收藏
Removal of TREX1 activity enhances CRISPR-Cas9-mediated homologous recombination
errNATURE BIOTECHNOLOGY
IF41.7
err2024-08-12
err1
errOAAI
errKarasu, Mehmet E.; Toufektchan, Eleonore; Chen, Yanyang; Albertelli, Alessandra; Cullot, Gregoire; Maciejowski, John; Corn, Jacob E.
err分享
err收藏
CCAR1 promotes DNA repair via alternative splicing
errMOLECULAR CELL
IF16.6
err2024-07-01
err1
errOAAI
errKarasu, Mehmet E.; Jahnke, Leonard; Joseph, Brian J.; Amerzhanova, Yerkezhan; Mironov, Aleksei; Shu, Xuan; Schroder, Markus S.; Gvozdenovic, Ana; Sala, Irene; Zavolan, Mihaela; Jonas, Stefanie; Corn, Jacob E.
err分享
err收藏
Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression
errMOLECULAR THERAPY
IF12
err2024-03-01
err0
errOAAI
errRajendiran, Vignesh; Devaraju, Nivedhitha; Haddad, Mahdi; Ravi, Nithin Sam; Panigrahi, Lokesh; Paul, Joshua; Gopalakrishnan, Chandrasekar; Wyman, Stacia; Ariudainambi, Keerthiga; Mahalingam, Gokulnath; Periyasami, Yogapriya; Prasad, Kirti; George, Anila; Sukumaran, Dhiyaneshwaran; Gopinathan, Sandhiya; Pai, Aswin Anand; Nakamura, Yukio; Balasubramanian, Poonkuzhali; Ramalingam, Rajasekaran; Thangavel, Saravanabhavan; Velayudhan, Shaji R.; Corn, Jacob E.; Mackay, Joel P.; Marepally, Srujan; Srivastava, Alok; Crossley, Merlin; Mohankumar, Kumarasamypet M.
err分享
err收藏
Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy表位工程化的人造血干细胞免受CD123-targeted免疫疗法的影响
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2023-09-29
err15
errOAAI
errMarone, Romina; Landmann, Emmanuelle; Devaux, Anna; Lepore, Rosalba; Seyres, Denis; Zuin, Jessica; Burgold, Thomas; Engdahl, Corinne; Capoferri, Giuseppina; Dell'Aglio, Alessandro; Larrue, Clement; Simonetta, Federico; Rositzka, Julia; Rhiel, Manuel; Andrieux, Geoffroy; Gallagher, Danielle N.; Schroder, Markus S.; Wiederkehr, Amelie; Sinopoli, Alessandro; Do Sacramento, Valentin; Haydn, Anna; Garcia-Prat, Laura; Divsalar, Christopher; Camus, Anna; Xu, Liwen; Bordoli, Lorenza; Schwede, Torsten; Porteus, Matthew; Tamburini, Jerome; Corn, Jacob E.; Cathomen, Toni; Cornu, Tatjana I.; Urlinger, Stefanie; Jeker, Lukas T.
err分享
err收藏
Engineering of the endogenous HBD promoter increases HbA2
errELIFE
IF0
err2023-06-02
err0
errOAAI
errBoontanrart, Mandy Y.; Machler, Elia; Ponta, Simone; Nelis, Jan C.; Preiano, Viviana G.; Corn, Jacob E.
err分享
err收藏
Semisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3
errACS CENTRAL SCIENCE
IF10.4
err2023-04-27
err5
errOAAI
errFarnung, Jakob; Muhar, Matthias; Liang, Jin Rui; Tolmachova, Kateryna A.; Benoit, Roger M.; Corn, Jacob E.; Bode, Jeffrey W.
err分享
err收藏
A CRISPR view on autophagy
errTRENDS IN CELL BIOLOGY
IF18.1
err2022-12-01
err5
errOAAI
errLiang, Jin Rui; Corn, Jacob E.
err分享
err收藏
Adenine base editing efficiently restores the function of Fanconi anemia hematopoietic stem and progenitor cells
errNATURE COMMUNICATIONS
IF15.7
err2022-11-12
err17
errOAAI
errSiegner, Sebastian M.; Ugalde, Laura; Clemens, Alexandra; Garcia-Garcia, Laura; Bueren, Juan A.; Rio, Paula; Karasu, Mehmet E.; Corn, Jacob E.
err分享
err收藏
Recursive Editing improves homology-directed repair through retargeting of undesired outcomes
errNATURE COMMUNICATIONS
IF15.7
err2022-08-05
err9
errOAAI
errMoeller, Lukas; Aird, Eric J.; Schroeder, Markus S.; Kobel, Lena; Kissling, Lucas; van de Venn, Lilly; Corn, Jacob E.
err分享
err收藏
Quantitative proteomic landscapes of primary and recurrent glioblastoma reveal a protumorigeneic role for FBXO2-dependent glioma-microenvironment interactions原发性和复发性胶质母细胞瘤的定量蛋白质组学景观揭示了FBXO2-dependent胶质瘤-微环境相互作用的原瘤作用
errNEURO-ONCOLOGY
IF13.4
err2022-07-08
err10
errOAAI
errBuehler, Marcel; Yi, Xiao; Ge, Weigang; Blattmann, Peter; Rushing, Elisabeth; Reifenberger, Guido; Felsberg, Joerg; Yeh, Charles; Corn, Jacob E.; Regli, Luca; Zhang, Junyi; Cloos, Ann; Ravi, Vidhya M.; Wiestler, Benedikt; Heiland, Dieter Henrik; Aebersold, Ruedi; Weller, Michael; Guo, Tiannan; Weiss, Tobias
err分享
err收藏

研究方向

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