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D

David P. Rotella

montclair state university

23H指数
158论文数
1.9K被引数
收录论文 35
发表时间
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Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties (vol 17, pg 547, 2026)强效、高选择性吡咯并嘧啶PDE11A4抑制剂，具有改善的药物性质（vol 17, pg 547, 2026）
errACS Medicinal Chemistry Letters
IF4
err2026-03-01
err0
PREAI
errMahmood, Shams Ul; Boddu, Rama Krishna; Eberhard, Jeremy; Hoffman, Charles S.; Gordon, John; Colussi, Dennis; Childers, Wayne; Amurrio, Elvis; Danaher, Marie; Kelly, Michy P.; Rotella, David P.
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Potent; Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties
errACS Medicinal Chemistry Letters
IF4
err2026-01-30
err0
errOAAI
errShams ul Mahmood; Rama Krishna Boddu; Jeremy Eberhard; Charles S. Hoffman; John Gordon; Dennis Colussi; Wayne Childers; Elvis Amurrio; Marie Danaher; Michy P. Kelly; David P. Rotella
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Versatile Imidazole Scaffold with Potent Activity against Multiple Apicomplexan Parasites多功能咪唑骨架，对多种顶复门寄生虫具有强效活性
errACS INFECTIOUS DISEASES
IF3.8
err2025-05-08
err0
errOAAI
errKhim, M; Montgomery, J; De Souza, ML; Delvillar, M; Weible, LJ; Prabakaran, M; Hulverson, MA; Eck, T; Bheemanabonia, RY; Alday, PH; Rotella, DP; Doggett, JS; Staker, BL; Ojo, KK; Bhanot, P
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First Demonstration of In Vivo PDE11A4 Target Engagement for Potential Treatment of Age-Related Memory Disorders
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-25
err0
errOAAI
errMahmood, Shams Ul; Eberhard, Jeremy; Hoffman, Charles S.; Colussi, Dennis; Gordon, John; Childers, Wayne; Amurrio, Elvis; Patel, Janvi; Kelly, Michy P.; Rotella, David P.
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Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials (vol 67, pg 3467, 2024)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-07-10
err0
PREAI
errGilleran, John A.; Ashraf, Kutub; Delvillar, Melvin; Eck, Tyler; Fondekar, Raheel; Miller, Edward B.; Hutchinson, Ashley; Dong, Aiping; Seitova, Alma; De Souza, Mariana Laureano; Augeri, David; Halabelian, Levon; Siekierka, John; Rotella, David P.; Gordon, John; Childers, Wayne E.; Grier, Mark C.; Staker, Bart L.; Roberge, Jacques Y.; Bhanot, Purnima
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Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-02-19
err3
PREAI
errGilleran, John A.; Ashraf, Kutub; Delvillar, Melvin; Eck, Tyler; Fondekar, Raheel; Miller, Edward B.; Hutchinson, Ashley; Dong, Aiping; Seitova, Alma; De Souza, Mariana Laureano; Augeri, David; Halabelian, Levon; Siekierka, John; Rotella, David P.; Gordon, John; Childers, Wayne E.; Grier, Mark C.; Staker, Bart L.; Roberge, Jacques Y.; Bhanot, Purnima
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First Optimization of Novel, Potent, Selective PDE11A4 Inhibitors for Age-Related Cognitive Decline
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-10-20
err2
errOAAI
errMahmood, Shams ul; Lozano Gonzalez, Mariana; Tummalapalli, Sreedhar; Eberhard, Jeremy; Ly, Judy; Hoffman, Charles; Kelly, Michy; Gordon, John; Colussi, Dennis; Childers, Wayne; Rotella, David
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Patrick M. Woster Memorial Commentary
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-10-03
err0
PREAI
errRotella, David P.; Georg, Gunda
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Patrick M. Woster Memorial Commentary
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-09-08
err0
PREAI
errRotella, David P.; Georg, Gunda
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A novel series of putative Brugia malayi histone demethylase inhibitors as potential anti-filarial drugs
errPLOS NEGLECTED TROPICAL DISEASES
IF3.4
err2022-03-16
err1
errOAAI
errKreiss, Tamara; Eck, Tyler; Hart, Brittany; Tummalapalli, Sreedhar; Rotella, David; Siekierka, John
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Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2021-11-15
err6
errOAAI
errBheemanaboina, Rammohan R. Yadav; Souza, Mariana Laureano de; Gonzalez, Mariana Lozano; Ul Mahmood, Shams; Eck, Tyler; Kreiss, Tamara; Aylor, Samantha O.; Roth, Alison; Lee, Patricia; Pybus, Brandon S.; Colussi, Dennis J.; Childers, Wayne E.; Gordon, John; Siekierka, John J.; Bhanot, Purnima; Rotella, David P.
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Plasmodium falciparum cGMP-Dependent Protein Kinase - A Novel Chemotherapeutic Target恶性疟原虫cGMP依赖性蛋白激酶 -- 一种新的化疗靶点
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2021-02-03
err12
errOAAI
errRotella, David; Siekierka, John; Bhanot, Purnima
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Discovery of isoxazolyl-based inhibitors of Plasmodium falciparum cGMP-dependent protein kinase
errRSC MEDICINAL CHEMISTRY
IF3.6
err2020-01-01
err8
errOAAI
errUl Mahmood, Shams; Cheng, Huimin; Tummalapalli, Sreedhar R.; Chakrasali, Ramappa; Bheemanaboina, Rammohan R. Yadav; Kreiss, Tamara; Chojnowski, Agnieska; Eck, Tyler; Siekierka, John J.; Rotella, David P.
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Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis淋巴丝虫病应激激活蛋白激酶抑制剂的发现
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2018-02-09
err6
errOAAI
errTummalapalli, Sreedhar R.; Bhat, Rohit; Chojnowski, Agnieszka; Prorok, Monika; Kreissir, Tamara; Goldberg, Ronald; Canan, Stacie; Hawryluk, Natalie; Mortensen, Deborah; Khetan, Vikram; Zeldis, Jerome; Siekierka, John J.; Rotella, David P.
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Mechanism of inhibition of botulinum neurotoxin type A light chain by two quinolinol compounds
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2017-03-01
err11
PREAI
errMinnow, Yacoba V. T.; Goldberg, Ronald; Tummalapalli, Sreedhar R.; Rotella, David P.; Goodey, Nina M.
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The Critical Role of Organic Chemistry in Drug Discovery有机化学在药物发现中的关键作用
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2016-09-13
err26
PREAI
errRotella, David P.
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Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2014-08-29
err121
PREAI
errBhat, Rohit; Tummalapalli, Sreedhar R.; Rotella, David P.
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The discovery and development of boceprevir
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2013-09-30
err22
PREAI
errRotella, David P.
err分享
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Gamma Secretase Modulators
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2013-08-09
err0
errOAAI
errRotella, David P.
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Substituted Benzylspiroindolin-2-one Analogues as Positive Allosteric Modulators of the Muscarinic Acetylcholine Receptor M1
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2013-08-09
err0
errOAAI
errRotella, David P.
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研究方向

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合作学者
合作期刊
Y
Yutaka Saito
H 指数: 89 · 论文数: 1.1K
J
Jerome B. Zeldis
H 指数: 65 · 论文数: 248
J
John A. Montgomery
H 指数: 64 · 论文数: 727
G
Gunda I. Georg
H 指数: 51 · 论文数: 620
A
Aiping Dong
H 指数: 49 · 论文数: 218
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