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P

Patrick M. Sexton

monash university
H指数:90
被引数:3.0万

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De novo design of miniproteins targeting GPCRs

从头设计靶向GPCRs的迷你蛋白

Nature
IF48.5
2026-05-210
PRE
Edin Muratspahić; David Feldman; David E. Kim; Xiangli Qu; Ana-Maria Bratovianu; Paula Rivera-Sánchez; Jan Hendrik Voss; Emil P. T. Hertz; Mads Jeppesen; Federica Dimitri; Kensuke Sakamoto; Amrita Nallathambi; Pia Peceli; Jianjun Cao; Brian P. Cary; Matthew J. Belousoff; Peter Keov; Phuc N. H. Trinh; Qingchao Chen; Yue Ren; Justyn Fine; Sudha Mishra; Annu Dalal; Shachie Sinha; Ramanuj Banerjee; Manisankar Ganguly; Karthik Varappalayam Karuppusamy; Isaac Sappington; Thomas Schlichthaerle; Jason Z. Zhang; Arvind Pillai; Brian Coventry; Ljubica Mihaljević; Magnus Bauer; Susana Vázquez Torres; Amir Motmaen; Gyu Rie Lee; Long Tran; Xinru Wang; Inna Goreshnik; Dionne K. Vafeados; Justin E. Svendsen; Parisa Hosseinzadeh; Nicolai Lindegaard; Matthäus Brandt; Yann Waltenspühl; Kristine Deibler; Lukas Deweid; Anja Bennett; Jendrik Schöppe; Tiantang Dong; Xiaoli Yan; Luke Oostdyk; William Cao; Lakshmi Anantharaman; Johan J. Weisser; Jesper Frank Bastlund; Christoffer Bundgaard; Ayodeji A. Asuni; Justin G. English; Lance Stewart; Lauren Halloran; Jamie B. Spangler; André Lieber; Arun K. Shukla; Patrick M. Sexton; Bryan L. Roth; Brian E. Krumm; Denise Wootten; Christopher G. Tate; Christoffer Norn; David Baker
In vivo functional profiling and structural characterization of the human GLP1R A316T variant
Science Advances
IF12.5
2026-02-040
OA
Liliane El Eid; Yusman Manchanda; Gregory Austin; Kieran Deane-Alder; Roxana-Maria Rujan; Zamara Mariam; Affiong I. Oqua; Matthew J. Belousoff; Jorge Bernardino de la Serna; Kyle W. Sloop; Guy A. Rutter; Alex Montoya; Dominic J. Withers; Steven J. Millership; Karim Bouzakri; Ben Jones; Christopher A. Reynolds; Patrick M. Sexton; Denise Wootten; Giuseppe Deganutti; Alejandra Tomas
A versatile antibody capture system drives specific in vivo delivery of mRNA-loaded lipid nanoparticles

一种多功能抗体捕获系统驱动了负载mRNA的脂质纳米颗粒在体内的特异性递送

Nature Nanotechnology
IF34.9
2025-08-040
OAAI
Moore Z. Chen; Daniel Yuen; Victoria M. McLeod; Ken W. Yong; Cameron H. Smyth; Bruna Rossi Herling; Thomas. J. Payne; Stewart A. Fabb; Matthew J. Belousoff; Azizah Algarni; Patrick M. Sexton; Christopher J. H. Porter; Colin W. Pouton; Angus P. R. Johnston
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR

Xanomeline在M4 mAChR处显示伴随的正构和变构结合模式

NATURE COMMUNICATIONS
IF15.7
2023-09-0610
OAAI
Burger, Wessel A. C.; Pham, Vi; Vuckovic, Ziva; Powers, Alexander S.; Mobbs, Jesse I.; Laloudakis, Yianni; Glukhova, Alisa; Wootten, Denise; Tobin, Andrew B.; Sexton, Patrick M.; Paul, Steven M.; Felder, Christian C.; Danev, Radostin; Dror, Ron O.; Christopoulos, Arthur; Valant, Celine; Thal, David M.

研究方向

暂未获取到该数据
A
Arthur Christopoulos
H 指数:95论文数:1,861被引数:4.1万
D
Denise Wootten
H 指数:52论文数:184被引数:9,146
C
Craig W. Lindsley
H 指数:86论文数:1,460被引数:3.0万
C
Céline Valant
H 指数:34论文数:110被引数:5,446
C
Carolyn R. Bertozzi
H 指数:140论文数:947被引数:8.4万
C
Cynthia J. Burrows
H 指数:65论文数:453被引数:1.4万
D
Deqing Zhang
H 指数:82论文数:881被引数:2.6万
M
Mary Beth Mulcahy
H 指数:5论文数:163被引数:160
J
Joel D. Blum
H 指数:88论文数:505被引数:2.4万
S
Shu Wang
H 指数:87论文数:974被引数:3.2万