Alan R. Saltiel - Publications, H-index & Citations

Alan R. Saltiel

departments of medicine and pharmacology

107H指数

387论文数

5.7W被引数

收录论文 154

发表时间

One drug, five targets 一种药物，五种靶点

Cell Research

IF25.9

2026-07-01

PREAI

Haipeng Fu; Alan R. Saltiel

Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover 膳食胆固醇激活依赖Ral的通路驱动LDLR周转

Nature

IF48.5

2026-06-24

PREAI

Xue Feng; Shuo Zhang; Yuqi Wang; Twisha Kurlagunda; Allyssa Sit; Priyadarshini Jaishankar; Pusu Yang; Sadatsugu Sakane; Se Yong Park; Churaibhon Wisessaowapak; Kaylee Nguyen; Jamie Yan; Himani Pothulu; Catherine Dinh; Felicia Chu; Yuyao Ren; Bichen Zhang; Patrick Secrest; Linmeng Han; Chao-Wei Hung; Preethi Veeragandham; Yuliya Skorobogatko; Tatiana Kisseleva; Philip L.S.M. Gordts; Adam R. Renslo; Peng Zhao; Amit R. Majithia; Alan R. Saltiel

Multi-layered transcriptional control of glycogen metabolism coordinates thermogenic remodeling of white adipocytes in male mice 多层级转录调控糖原代谢，协调雄性小鼠白色脂肪细胞的产热重塑。

Nature Communications

IF15.7

2025-12-16

OAAI

Haipeng Fu; Seoyeon Lee; Nathan R. Zemke; Weiwei Fan; Yunqing Wang; James Garza; David Tin; Bryce Villao; Bichen Zhang; Xianda Ma; Jinyang Zhang; Tangran Dong; Yuyao Ren; Michael Downes; Ronald M. Evans; Bing Ren; Alan R. Saltiel

Neutrophils preserve energy storage in sympathetically activated adipocytes 中性粒细胞维持交感神经激活的脂肪细胞中的能量储存

Nature

IF48.5

2025-12-10

PREAI

Seunghwan Son; Cindy Xu; Haipeng Fu; Churaibhon Wisessaowapak; Joseph M. Valentine; Garam An; Janice Jang; Maddox Dinh; Yang Dai; Weiwei Fan; Ruth T. Yu; Michael Downes; Wei Ying; Yuliya Skorobogatko; Ronald M. Evans; Alan R. Saltiel

Pedro Cuatrecasas (1936–2025)

Nature Biotechnology

IF41.7

2025-12-03

PREAI

Alan R. Saltiel

Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation

NATURE METABOLISM

IF20.8

2024-01-29

OAAI

Xia, Wenmin; Veeragandham, Preethi; Cao, Yu; Xu, Yayun; Rhyne, Torrey E.; Qian, Jiaxin; Hung, Chao-Wei; Zhao, Peng; Jones, Ying; Gao, Hui; Liddle, Christopher; Yu, Ruth T.; Downes, Michael; Evans, Ronald M.; Ryden, Mikael; Wabitsch, Martin; Wang, Zichen; Hakozaki, Hiroyuki; Schoneberg, Johannes; Reilly, Shannon M.; Huang, Jianfeng; Saltiel, Alan R.

Obesity-Induced Mitochondrial Fragmentation in White Adipocytes Is Controlled by the Small GTPase RalA

DIABETES

IF7.5

2023-06-20

PREAI

Xia, Wenmin; Veeragandham, Preethi; Cao, Yu; Xu, Yayun; Rhyne, Torrey E.; Jones, Ying; Yu, Ruth T.; Ryden, Mikael; Wabitsch, Martin; Saltiel, Alan

Hepatic Glycogen Directly Regulates Gluconeogenesis in Energy Shortage through AMPK

DIABETES

IF7.5

2023-06-20

PREAI

Zhang, Bichen; Johnson, Morgan M.; Yuan, Timothy; Tammy-Nhu Nguyen; Saltiel, Alan

Increased Glucose Uptake in Brown Fat Promotes Energy Expenditure

DIABETES

IF7.5

2023-06-20

PREAI

Rezayat, Farid; Resnick, Julie A.; Farah, Isabella M.; Skorobogatko, Yuliya; Saltiel, Alan

Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness 果糖-1，6-双磷酸酶是一种非酶安全阀，可减少AKT激活以防止胰岛素高反应性

CELL METABOLISM

IF30.9

2023-06-01

OAAI

Gu, Li; Zhu, Yahui; Watari, Kosuke; Lee, Maiya; Liu, Junlai; Perez, Sofia; Thai, Melinda; Mayfield, Joshua E.; Zhang, Bichen; Cunha e Rocha, Karina; Li, Fuming; Kim, Laura C.; Jones, Alexander C.; Wierzbicki, Igor H.; Liu, Xiao; Newton, Alexandra C.; Kisseleva, Tatiana; Lee, Jun Hee; Ying, Wei; Gonzalez, David J.; Saltiel, Alan R.; Simon, M. Celeste; Karin, Michael

A novel, multifunctional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

213

OAAI

Ribon, V; Printen, JA; Hoffman, NG; Kay, BK; Saltiel, AR

APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

175

OAAI

Liu, J; Kimura, A; Baumann, CA; Saltiel, AR

The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Watson, RT; Furukawa, M; Chiang, SH; Boeglin, D; Kanzaki, M; Saltiel, AR; Pessin, JE

White Adipose Tissue Glycogen Regulates Exercise Capacity and Metabolism

DIABETES RESEARCH AND CLINICAL PRACTICE

IF7.4

2023-03-01

PREAI

Rovira-Llopis, S.; Deshpande, S. S. S.; Columbus, M. M.; Hirshman, M. F.; Keinan, O.; Saltiel, A. R.; Goodyear, L. J.

The TBK1/IKKε inhibitor amlexanox improves dyslipidemia and prevents atherosclerosis TBK1/ikk ε 抑制剂amlexanox改善血脂异常并预防动脉粥样硬化

JCI INSIGHT

IF6.1

2022-09-08

OAAI

Zhao, Peng; Sun, Xiaoli; Liao, Zhongji; Yu, Hong; Li, Dan; Shen, Zeyang; Glass, Christopher K.; Witztum, Joseph L.; Saltiel, Alan R.

Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome

CELL REPORTS

IF6.9

2022-07-01

OAAI

Machado, Ana Carolina Dantas; Brown, Steven D.; Lingaraju, Amulya; Sivaganesh, Vignesh; Martino, Cameron; Chaix, Amandine; Zhao, Peng; Pinto, Antonio F. M.; Chang, Max W.; Richter, R. Alexander; Saghatelian, Alan; Saltiel, Alan R.; Knight, Rob; Panda, Satchidananda; Zarrinpar, Amir

β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2022-01-18

OAAI

Valentine, Joseph M.; Ahmadian, Maryam; Keinan, Omer; Abu-Odeh, Mohammad; Zhao, Peng; Zhou, Xin; Keller, Mark P.; Gao, Hui; Yu, Ruth T.; Liddle, Christopher; Downes, Michael; Zhang, Jin; Lusis, Aldons J.; Attie, Alan D.; Evans, Ronald M.; Ryden, Mikael; Saltier, Alan R.

300 or CBP is required for insulin- stimulated glucose uptake in skeletal muscle and adipocytes

JCI INSIGHT

IF6.1

2022-01-11

OAAI

Martins, Vitor F.; LaBarge, Samuel A.; Stanley, Alexandra; Svensson, Kristoffer; Hung, Chao-Wei; Keinan, Omer; Ciaraldi, Theodore P.; Banoian, Dion; Park, Ji E.; Ha, Christina; Hetrick, Byron; Meyer, Gretchen A.; Philp, Andrew; David, Larry L.; Henry, Robert R.; Aslan, Joseph E.; Saltiel, Alan R.; McCurdy, Carrie. E.; Schenk, Simon

Roles of IκB kinases and TANK-binding kinase 1 in hepatic lipid metabolism and nonalcoholic fatty liver disease

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2021-11-30

OAAI

Huh, Jin Young; Saltiel, Alan R.

Chop/Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-07-28

OAAI

Yong, Jing; Parekh, Vishal S.; Reilly, Shannon M.; Nayak, Jonamani; Chen, Zhouji; Lebeaupin, Cynthia; Jang, Insook; Zhang, Jiangwei; Prakash, Thazha P.; Sun, Hong; Murray, Sue; Guo, Shuling; Ayala, Julio E.; Satin, Leslie S.; Saltiel, Alan R.; Kaufman, Randal J.

研究方向