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W

Wesley C. Van Voorhis

university of washington
H指数:72
被引数:1.8万

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Bumped Kinase Inhibitor BKI-1708 Interferes in Cytokinesis and Drives Baryzoite Conversion in the Cyst-Forming Apicomplexan Parasites Toxoplasma gondii, Neospora caninum and Besnoitia besnoiti

碰撞激酶抑制剂BKI-1708干扰细胞分裂并驱动包囊形成顶复门寄生虫弓形虫、新孢子虫和贝氏贝诺虫的类囊体转化

International Journal of Molecular Sciences
IF4.9
2026-03-300
OAAI
Maria Cristina Ferreira de Sousa; Joachim Müller; Kai Pascal Alexander Hänggeli; Manfred Heller; Anne-Christine Uldry; Sophie Braga-Lagache; Alexandre Leitao; Luis-Miguel Ortega-Mora; Kayode K. Ojo; Wesley C. Van Voorhis; Andrew Hemphill
Pharmacokinetic analysis of bumped-kinase inhibitors in horses demonstrates their potential utility for prevention and treatment of equine protozoal myeloencephalitis

马匹中凸起激酶抑制剂的药代动力学分析表明其在预防与治疗马原虫性脑脊髓炎方面的潜在应用价值

American Journal of Veterinary Research
IF1.4
2026-01-010
PRE
Rocha, Izabela de Assis; McPeek, Jenna L.; Hulverson, Matthew A.; Choi, Ryan; Orr, Kindra; Sponseller, Beatrice T.; Kennedy, Tom; Ojo, Kayode K.; Barrett, Lynn K.; Ruby, Rebecca; Janes, Jennifer; Reed, Stephen M.; Arnold, Samuel L. M.; Van Voorhis, Wesley C.; Page, Allen; Howe, Daniel K.
Effective Treatment using Bumped Kinase Inhibitor 1708 in a Calf Clinical Model of Cryptosporidiosis

使用1708凸起激酶抑制剂对牛临床模型的隐孢子虫病进行有效治疗

The Journal of Infectious Diseases
IF0
2026-01-010
OA
Deborah A Schaefer; Dana P Betzer; Kevin Ackman; Elizabeth Carranza-Acevedo; Paula Grijalva; Elizabeth Miller; Karissa Pottorff; Elina Landeros Rivas; Kayode K Ojo; Matthew A Hulverson; Samuel L M Arnold; Wenlin Huang; Ryan Choi; Lynn K Barrett; Erkang Fan; Wesley C Van Voorhis; Michael W Riggs
Reemergence of yellow fever virus in forest and periurban settings in Brazil

巴西森林和城郊地区黄热病毒的再出现

Communications Medicine
IF6.3
2025-12-150
OAAI
Valnete das Graças Dantas Andrade; Talita Émile Ribeiro Adelino; Vagner Fonseca; Keldenn Melo Farias Moreno; Luiz Marcelo Ribeiro Tomé; Luiz Augusto Pereira; Debora Glenda Lima de La-Roque; Ana Maria Bispo de Filippis; Daniel Garkauskas Ramos; Dario Brock Ramalho; Kátia Cristina de Lima Furtado; Gleissy Adriane Lima Borges; Livia Caricio Martins; Livia C. V. Frutuoso; Ludmila Oliveira Lamounier; Natália Rocha Guimarães; Patrícia Miriam Sayuri Sato Barros; Priscila Souza de Almeida; Paulo Eduardo de Souza da Silva; Rodrigo Giesbrecht Pinheiro; Rodrigo Guerino Stabeli; Shirley Moreira da Silva Chagas; Sílvia Helena Sousa Pietra Pedroso; Simone Kashima; Solange Gonçalves Penante; Marília Santini de Oliveira; Vinicius Lemes da Silva; Wesley C. Van Voorhis; Edward C. Holmes; José Lourenço; Felipe Campos de Melo Iani; Alberto Simões Jorge Júnior; Marta Giovanetti; Luiz Carlos Junior Alcantara
Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD+-bound protomer chains

Brucella ovis来源的短链脱氢酶的晶体结构，包含apo形式和结合NAD+辅酶的原聚体链

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS
IF1.1
2025-12-010
OA
Zupko, Sean P.; Konstanty, Amelia T.; Mayclin, Steve J.; Choi, Ryan; Serbzhinskiy, Dmitry; Robles, Emily; Moses, Victoria; Barrett, Lynn K.; Van Voorhis, Wesley C.; Edwards, Tom E.; Myler, Peter J.; Torelli, Andrew T.; French, Jarrod B.; Hicks, Katherine A.
Dose-dependent tissue tropism and efficacy of early BKI-1748 treatment in chronic Toxoplasma gondii infection in sheep

剂量依赖性的组织嗜性及早期BKI-1748治疗在慢性弓形虫感染羊中的疗效

Food and Waterborne Parasitology
IF3.1
2025-10-260
OAAI
Roberto Sánchez-Sánchez; Rafael Calero-Bernal; Natalia Velasco-Jiménez; Irene Gallego-Moreno; Carmen Pérez Díaz; Rocío Bustamante; Ryan Choi; Matthew A. Hulverson; Andrew Hemphill; Wesley C. Van Voorhis; Luis Miguel Ortega-Mora
Enhancing SARS-CoV-2 Response Capacity in Africa and Other CREID Centers through a Collaborative Training Program

通过合作培训计划增强非洲及其他CREID中心对SARS-CoV-2的响应能力

Clinical Microbiology and Infection
IF8.5
2025-10-110
PRE
Ambroise Ahouidi; Abdou Padane; Alioune Gaye; Anavaj Sakuntabha; Awa Deme; Badara Cisse; Carla de Oliveira; Caroline Weldon; Cyrille Diedhiou; Daouda Ndiaye; Geoffrey S. Gottlieb; Helene McOwen; Ibrahima Dia; Joilson Xavier; Katherine J. Siddle; Kristian Andersen; Lynn Barrett; Mariétou Faye Paye; Mawlouth Diallo; Sasha Tilles; Scott C. Weaver; Shirlee Wohl; Tulio de Oliveira; Luiz Carlos Junior Alcantara; Wesley C. Van Voorhis; Souleymane Mboup; Eduan Wilkinson; Marta Giovanetti
Clinical characteristics and serotype association of dengue and dengue like illness in Pakistan

巴基斯坦登革热及登革热样疾病的临床特征与血清型关联

PLOS NEGLECTED TROPICAL DISEASES
IF3.4
2025-05-120
OA
Iqbal, Najeeha Talat; Ahmed, Kumail; Khalid, Aqsa; Imtiaz, Kehkashan; Ali, Qamreen Mumtaz; Munir, Tania; Mahmood, Syed Faisal; Khan, Unab; Afzal, Badar; Qamar, Farah Naz; Waggoner, Jesse J.; Fenelon, Hannah; McOwen, Helene; Khan, Erum; Rabinowitz, Peter; Van Voorhis, Wesley C.
Structure guided modification of 2-chloro-5-(ethyl-phenyl-sulfamoyl)-N-[2-(2-oxo-pyrrolidin-1-yl)-phenyl]-benzamide to afford selective inhibitors of Cryptosporidium parvum N-myristoyltransferase

在2-氯-5-（乙基苯磺酰氨基）-N-[2-（2-氧代吡咯烷-1-基）苯基]苯甲酰胺的指导下进行结构修饰，以制备隐孢子虫微小种N-豆蔻酰转移酶的选择性抑制剂

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
IF2.2
2025-04-010
PRE
Sigalapalli, Dilep K.; Groustra, Sophia; Fenwick, Michael K.; Zigweid, Rachael; Hulverson, Matthew A.; Owsley, Eric; Khim, Monique; Shibata, Sayaka; Van Voorhis, Wesley C.; Staker, Bart L.; Fan, Erkang
Treatment with BKI-1748 after Toxoplasma gondii systemic dissemination in experimentally infected pregnant sheep improves fetal and lamb mortality and morbidity and prevents congenital infection
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2025-02-132
PRE
Sanchez-Sanchez, Roberto; Huertas-Lopez, Ana; Largo-de la Torre, Andrea; Ferre, Ignacio; Dini, Filippo Maria; Re, Michela; Moreno-Gonzalo, Javier; Choi, Ryan; Hulverson, Matthew A.; Ojo, Kayode K.; Arnold, Samuel L. M.; Hemphill, Andrew; Van Voorhis, Wesley C.; Ortega-Mora, Luis Miguel
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens
COMMUNICATIONS BIOLOGY
IF5.1
2024-12-050
OAAI
Fenwick, Michael K.; Pierce, Phillip G.; Abendroth, Jan; Barrett, Kayleigh F.; Barrett, Lynn K.; Bowatte, Kalinga; Choi, Ryan; Chun, Ian; Conrady, Deborah G.; Craig, Justin K.; Dranow, David M.; Hammerson, Bradley; Higgins, Tate; Lorimer, Donald D.; Lukat, Peer; Mayclin, Stephen J.; Hewitt, Stephen Nakazawa; Peng, Ying Po; Shanbhogue, Ashwini; Smutney, Hayden; Stigliano, Matthew Z. Z.; Tillery, Logan M.; Udell, Hannah S.; Wallace, Ellen G.; Derocher, Amy E.; Phan, Isabelle Q.; Staker, Bart L.; Subramanian, Sandhya; Van Voorhis, Wesley C.; Blankenfeldt, Wulf; Mueller, Rolf; Edwards, Thomas E.; Myler, Peter J.
Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
IF3.4
2024-08-010
OAAI
de Sousa, Maria Cristina Ferreira; Imhof, Dennis; Hanggeli, Kai Pascal Alexander; Choi, Ryan; Hulverson, Matthew A.; Arnold, Samuel L. M.; Van Voorhis, Wesley C.; Fan, Erkang; Roberto, Sanchez-Sanchez; Ortega-Mora, Luis M.; Hemphill, Andrew
A Compound That Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-06-121
OA
Uo, Takuma; Ojo, Kayode K.; Sprenger, Cynthia C. T.; Epilepsia, Kathryn S.; Perera, B. Gayani K.; Damodarasamy, Mamatha; Sun, Shihua; Kim, Soojin; Hogan, Hannah H.; Hulverson, Matthew A.; Choi, Ryan; Whitman, Grant R.; Barrett, Lynn K.; Michaels, Samantha A.; Xu, Linda H.; Sun, Vicky L.; Arnold, Samuel L. M.; Pang, Haley J.; Nguyen, Matthew M.; Vigil, Anna-Lena B. G.; Kamat, Varun; Sullivan, Lucas B.; Sweet, Ian R.; Vidadala, Ram; Maly, Dustin J.; Van Voorhis, Wesley C.; Plymate, Stephen R.
Clofazimine pharmacokinetics in HIV-infected adults with diarrhea: Implications of diarrheal disease on absorption of orally administered therapeutics
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
2024-01-023
OA
Zhang, Cindy X.; Conrad, Thomas M.; Hermann, David; Gordon, Melita A.; Houpt, Eric; Iroh Tam, Pui-Ying; Jere, Khuzwayo C.; Nedi, Wilfred; Operario, Darwin J.; Phulusa, Jacob; Quinnan, Gerald V.; Sawyer, Leigh A.; Barrett, Lynn K.; Thole, Herbert; Toto, Neema; Van Voorhis, Wesley C.; Arnold, Samuel L. M.
An Early Treatment With BKI-1748 Exhibits Full Protection Against Abortion and Congenital Infection in Sheep Experimentally Infected With Toxoplasma gondii
JOURNAL OF INFECTIOUS DISEASES
IF4.5
2023-10-276
PRE
Sanchez-Sanchez, Roberto; Imhof, Dennis; Hecker, Yanina P.; Ferre, Ignacio; Re, Michela; Moreno-Gonzalo, Javier; Blanco-Murcia, Javier; Mejias-Lopez, Elena; Hulverson, Matthew A.; Choi, Ryan; Arnold, Samuel L. M.; Ojo, Kayode K.; Barrett, Lynn K.; Hemphill, Andrew; Van Voorhis, Wesley C.; Ortega-Mora, Luis Miguel

研究方向

暂未获取到该数据
K
Kayode K. Ojo
H 指数:41论文数:235被引数:4,766
R
Ryan Choi
H 指数:28论文数:233被引数:2,338
M
Matthew A. Hulverson
H 指数:24论文数:155被引数:1,526
L
Lynn K. Barrett
H 指数:33论文数:201被引数:2,940
E
Erkang Fan
H 指数:44论文数:246被引数:6,376
D
Dustin J. Maly
H 指数:48论文数:320被引数:6,738
S
Samuel L.M. Arnold
H 指数:24论文数:174被引数:1,570
G
Grant R. Whitman
H 指数:17论文数:134被引数:771
C
Christophe L. M. J. Verlinde
H 指数:48论文数:199被引数:7,756
A
Andrew Hemphill
H 指数:63论文数:461被引数:1.3万