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L

Larry A. Sklar

university of new mexico
H指数:81
被引数:2.5万

个人简介

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教育背景

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工作经历

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荣誉奖项

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RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-03-1523
OA
Matthijssens, Filip; Sharma, Nitesh D.; Nysus, Monique; Nickl, Christian K.; Kang, Huining; Perez, Dominique R.; Lintermans, Beatrice; Van Loocke, Wouter; Roels, Juliette; Peirs, Sofie; Demoen, Lisa; Pieters, Tim; Reunes, Lindy; Lammens, Tim; De Moerloose, Barbara; Van Nieuwerburgh, Filip; Deforce, Dieter L.; Cheung, Laurence C.; Kotecha, Rishi S.; Risseeuw, Martijn D. P.; Van Calenbergh, Serge; Takarada, Takeshi; Yoneda, Yukio; van Delft, Frederik W.; Lock, Richard B.; Merkley, Seth D.; Chigaev, Alexandre; Sklar, Larry A.; Mullighan, Charles G.; Loh, Mignon L.; Winter, Stuart S.; Hunger, Stephen P.; Goossens, Steven; Castillo, Eliseo F.; Ornatowski, Wojciech; Van Vlierberghe, Pieter; Matlawska-Wasowska, Ksenia
Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-09-0933
OAAI
Rai, Ganesha; Urban, Daniel J.; Mott, Bryan T.; Hu, Xin; Yang, Shyh-Ming; Benavides, Gloria A.; Johnson, Michelle S.; Squadrito, Giuseppe L.; Brimacombe, Kyle R.; Lee, Tobie D.; Cheff, Dorian M.; Zhu, Hu; Henderson, Mark J.; Pohida, Katherine; Sulikowski, Gary A.; Dranow, David M.; Kabir, Md; Shah, Pranav; Padilha, Elias; Tao, Dingyin; Fang, Yuhong; Christov, Plamen P.; Kim, Kwangho; Jana, Somnath; Muttil, Pavan; Anderson, Tamara; Kunda, Nitesh K.; Hathaway, Helen J.; Kusewitt, Donna F.; Oshima, Nobu; Cherukuri, Murali; Davies, Douglas R.; Norenberg, Jeffrey P.; Sklar, Larry A.; Moore, William J.; Dang, Chi, V; Stott, Gordon M.; Neckers, Leonard; Flint, Andrew J.; Darley-Usmar, Victor M.; Simeonov, Anton; Waterson, Alex G.; Jadhav, Ajit; Hall, Matthew D.; Maloney, David J.
Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

肿瘤中LDH抑制的动态成像揭示了快速的体内代谢重组和对联合治疗的脆弱性

CELL REPORTS
IF6.9
2020-02-0181
OAAI
Oshima, Nobu; Ishida, Ryo; Kishimoto, Shun; Beebe, Kristin; Brender, Jeffrey R.; Yamamoto, Kazutoshi; Urban, Daniel; Rai, Ganesha; Johnson, Michelle S.; Benavides, Gloria; Squadrito, Giuseppe L.; Crooks, Dan; Jackson, Joseph; Joshi, Abhinav; Mott, Bryan T.; Shrimp, Jonathan H.; Moses, Michael A.; Lee, Min-Jung; Yuno, Akira; Lee, Tobie D.; Hu, Xin; Anderson, Tamara; Kusewitt, Donna; Hathaway, Helen H.; Jadhav, Ajit; Picard, Didier; Trepel, Jane B.; Mitchell, James B.; Stott, Gordon M.; Moore, William; Simeonov, Anton; Sklar, Larry A.; Norenberg, Jeffrey P.; Linehan, W. Marston; Maloney, David J.; Dang, Chi V.; Waterson, Alex G.; Hall, Matthew; Darley-Usmar, Victor M.; Krishna, Murali C.; Neckers, Leonard M.
Autophagy, Inflammation, and Metabolism (AIM) Center in its second year
AUTOPHAGY
IF14.3
2019-07-151
OAAI
Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J.; Cannon, Judy; Liu, Ke Jian; Liu, Meilian; Hall, Pamela; Sklar, Larry A.; Allers, Lee; Mariscal, Luisa; Garcia, Sally Ann; Weaver, John; Baehrecke, Eric H.; Behrends, Christian; Cecconi, Francesco; Codogno, Patrice; Chen, Guang-Chao; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fourie, Bernard; Gozuacik, Devrim; Hong, Wanjin; Jo, Eun-Kyeong; Johansen, Terje; Juhasz, Gabor; Kimch, Adi; Ktistakis, Nicholas; Kroemer, Guido; Mizushima, Noboru; Muenz, Christian; Reggiori, Fulvio; Rubinsztein, David; Ryan, Kevin; Schroder, Kate; Shen, Han-Min; Simonsen, Anne; Tooze, Sharon A.; Vaccaro, Maria; Yoshimori, Tamotsu; Yu, Li; Zhang, Hong; Klionsky, Daniel J.
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

自噬，炎症和代谢 (AIM) 生物医学研究卓越中心: 支持下一代自噬研究人员并促进国际合作

AUTOPHAGY
IF14.3
2018-06-233
OAAI
Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J.; Cannon, Judy; Liu, Ke Jian; Sklar, Larry A.; Allers, Lee; Garcia, Sally Ann; Baehrecke, Eric H.; Behrends, Christian; Cecconi, Francesco; Codogno, Patrice; Chen, Guang-Chao; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fourie, Bernard; Gozuacik, Devrim; Hong, Wanjin; Hotamisligi, Gokhan; Jaaettela, Marja; Jo, Eun-Kyeong; Johansen, Terje; Juhasz, Gabor; Kimchi, Adi; Ktistakis, Nicholas; Kroemer, Guido; MIzushima, Noboru; Munz, Christian; Reggiori, Fulvio; Rubinsztein, David; Ryan, Kevin; Schroder, Kate; Simonsen, Anne; Tooze, Sharon; Vaccaro, Maria I.; Yoshimori, Tamotsu; Yu, Li; Zhang, Hong; Klionsky, Daniel J.
Activation of Rho Family GTPases by Small Molecules
ACS CHEMICAL BIOLOGY
IF3.8
2018-05-1016
OAAI
Palsuledesai, Charuta C.; Suryiladze, Zurab; Waller, Anna; Miscioscia, T. Fabiola; Guo, Yuna; Wu, Yang; Strouse, Jake; Romero, Elsa; Salas, Virginia M.; Curpan, Ramona; Young, Susan; Carter, Mark; Foutz, Terry; Galochkina, Zhanna; Ames, Harold; Haynes, Mark K.; Edwards, Bruce S.; Nicolotti, Orazio; Luo, Li; Ursu, Oleg; Bologa, Cristian G.; Oprea, Tudor, I; Wandinger-Ness, Angela; Sklar, Larry A.
Unexplored therapeutic opportunities in the human genome (vol 17, pg 317, 2018)

人类基因组中未开发的治疗机会 (第17卷，317页，2018页)

NATURE REVIEWS DRUG DISCOVERY
IF101.8
2018-03-2323
OAAI
Oprea, Tudor I.; Bologa, Cristian G.; Brunak, Soren; Campbell, Allen; Gan, Gregory N.; Gaulton, Anna; Gomez, Shawn M.; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L.; Karlson, Anneli; Leach, Andrew R.; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Steven L.; McManus, Michael T.; Meehan, Terrence F.; von Mering, Christian; Muthas, Daniel; Dac-Trung Nguyen; Overington, John P.; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L.; Schurer, Stephan C.; Simeonov, Anton; Sklar, Larry A.; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Dusica; Waller, Anna; Westergaard, David; Yang, Jeremy J.; Zahoranszky-Kohalmi, Gergely
Unexplored therapeutic opportunities in the human genome

人类基因组中未开发的治疗机会

NATURE REVIEWS DRUG DISCOVERY
IF101.8
2018-03-23278
OAAI
Oprea, Tudor I.; Bologa, Cristian G.; Brunak, Soren; Campbell, Allen; Gan, Gregory N.; Gaulton, Anna; Gomez, Shawn M.; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L.; Karlson, Anneli; Leach, Andrew R.; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Stephen L.; McManus, Michael T.; Meehan, Terrence F.; von Mering, Christian; Muthas, Daniel; Dac-Trung Nguyen; Overington, John P.; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L.; Schurer, Stephan C.; Simeonov, Anton; Sklar, Larry A.; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Dusica; Waller, Anna; Westergaard, David; Yang, Jeremy J.; Zahoranszky-Kohalmi, Gergely
Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2018-01-0476
OAAI
Tissino, Erika; Benedetti, Dania; Herman, Sarah E. M.; ten Hacken, Elisa; Ahn, Inhye E.; Chaffee, Kari G.; Rossi, Francesca Maria; Dal Bo, Michele; Bulian, Pietro; Bomben, Riccardo; Bayer, Elisabeth; Haerzschel, Andrea; Gutjahr, Julia Christine; Postorino, Massimiliano; Santinelli, Enrico; Ayed, Ayed; Zaja, Francesco; Chiarenza, Annalisa; Pozzato, Gabriele; Chigaev, Alexandre; Sklar, Larry A.; Burger, Jan A.; Ferrajoli, Alessandra; Shanafelt, Tait D.; Wiestner, Adrian; Del Poeta, Giovanni; Hartmann, Tanja Nicole; Gattei, Valter; Zucchetto, Antonella
Pharos: Collating protein information to shed light on the druggable genome

Pharos: 整理蛋白质信息以阐明可药用基因组

NUCLEIC ACIDS RESEARCH
IF13.1
2016-11-29189
OAAI
Dac-Trung Nguyen; Mathias, Stephen; Bologa, Cristian; Brunak, Soren; Fernandez, Nicolas; Gaulton, Anna; Hersey, Anne; Holmes, Jayme; Jensen, Lars Juhl; Karlsson, Anneli; Liu, Guixia; Ma'ayan, Avi; Mandava, Geetha; Mani, Subramani; Mehta, Saurabh; Overington, John; Patel, Juhee; Rouillard, Andrew D.; Schurer, Stephan; Sheils, Timothy; Simeonov, Anton; Sklar, Larry A.; Southall, Noel; Ursu, Oleg; Vidovic, Dusica; Waller, Anna; Yang, Jeremy; Jadhav, Ajit; Oprea, Tudor I.; Guha, Rajarshi

研究方向

暂未获取到该数据
E
Eric R. Prossnitz
H 指数:81论文数:323被引数:2.3万
T
Tudor I. Oprea
H 指数:85论文数:510被引数:2.8万
B
Bruce S. Edwards
H 指数:34论文数:225被引数:4,814
A
Alexandre Chigaev
H 指数:24论文数:59被引数:2,307
A
Anna Waller
H 指数:34论文数:229被引数:5,458
O
Oleg Ursu
H 指数:30论文数:139被引数:7,304
T
Tione Buranda
H 指数:30论文数:131被引数:2,887
J
Jeffrey B. Arterburn
H 指数:38论文数:136被引数:8,779
C
Cristian Bologa
H 指数:0论文数:2被引数:43
T
Terry D. Foutz
H 指数:15论文数:73被引数:516