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B

Brian J.P. Huntly

University of Cambridge

64H指数
334论文数
2.3W被引数
收录论文 92
发表时间
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Author Correction: Timing and trajectory of BCR::ABL1-driven chronic myeloid leukaemia作者更正：BCR::ABL1驱动的慢性髓性白血病的时机和轨迹
errNature
IF48.5
err2026-10-12
err0
errOAAI
errAleksandra E. Kamizela; Daniel Leongamornlert; Nicholas Williams; Xin Wang; Kudzai Nyamondo; Kevin Dawson; Michael Spencer Chapman; Jing Guo; Joe Lee; Karim Mane; Kate Milne; Anthony R. Green; Timothy Chevassut; Peter J. Campbell; Patrick T. Ellinor; Brian J. P. Huntly; E. Joanna Baxter; Jyoti Nangalia
err分享
err收藏
A step-wise, deterministic and fatal mouse model of myeloid neoplasm with spontaneous acquisition of patient-relevant RTK–RAS mutations分步、确定性且致命的小鼠髓系肿瘤模型，可自发获得与患者相关的RTK–RAS突变
errOncogene
IF7.3
err2026-09-04
err0
errOAAI
errMarija A. Zarocsinceva; Moosa Qureshi; Nicola K. Wilson; George Giotopoulos; Blaise Musabe; Katherine H. M. Sturgess; M. S. Vijayabaskar; Sarah J. Kinston; Ryan Asby; David J. Adams; Brian J. P. Huntly; Fernando J. Calero-Nieto; Berthold Göttgens
err分享
err收藏
Machine learning provides individualized prediction of outcomes after first complete remission without allo-HSCT consolidation in adult acute myeloid leukemia—A HARMONY study机器学习为成人急性髓系白血病首次完全缓解后无allo-HSCT巩固治疗的患者结局提供个体化预测——一项HARMONY研究
errHemaSphere
IF14.6
err2026-08-31
err0
errOAAI
errAlberto Hernández-Sánchez; Javier Martínez Elicegui; Eric Sträng; Axel Benner; Marta Sobas; Ángela Villaverde Ramiro; Amin T. Turki; María Abáigar; Gastone Castellani; Jurjen Versluis; Ian Thomas; Jesse M. Tettero; Rabea Mecklenbrauck; Joaquín Martínez-López; Marta Pratcorona; Guillermo Sanz; Maria Teresa Voso; Sören Lehmann; Christoph Röllig; Klaus H. Metzeler; Konstanze Döhner; Michael Heuser; Torsten Haferlach; Peter J. M. Valk; Jesús María Hernández-Rivas; Brian J. P. Huntly; Gert Ossenkoppele; Hartmut Döhner; Lars Bullinger
err分享
err收藏
The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferationNAT10的RNA解旋酶结构域通过促进低修饰核糖体的生物发生来增强癌细胞增殖
errNature Communications
IF15.7
err2026-08-08
err0
errOAAI
errMahmood H. Dalhat; Sharath Narayan; Maria Eleftheriou; James Russell; James Heslop; Hannah Serio; Khulood A. Alzahrani; Adam Suh; Ajay Edakkara; Sweta Raikundalia; Lea Landmann; Ryan Asby; Evangelia Stamou; Judith López; Yogeshkumar Malam; Demetrios Aspris; Emmely A. Patrasso; Stephanie Mou; George Giotopoulos; Walid T. Khaled; Brian J. P. Huntly; Fotios Sampaziotis; Konstantinos Tzelepis; Daniel Arango
err分享
err收藏
Prognostic impact of myelodysplasia-related gene mutations in FLT3-ITD-mutated acute myeloid leukemiaFLT3-ITD突变急性髓系白血病中髓系发育异常相关基因突变的预后影响
errLeukemia
IF13.4
err2026-02-09
err0
errOAAI
errRabea Mecklenbrauck; Angela Villaverde Ramiro; Eric Sträng; Razif Gabdoulline; Javier Martinez Elicegui; Marta Sobas; Lisa Pleyer; Amin Turki; Maria Teresa Voso; Axel Benner; Alberto Hernández-Sánchez; Jesse M. Tettero; Laura Tur Gimenez; Klaus H. Metzeler; Guadalupe Oñate; Sören Lehmann; Brian JP Huntly; Ian Thomas; Felicitas R. Thol; Florian H. Heidel; Peter JM Valk; Konstanze Döhner; Torsten Haferlach; Kenneth I. Mills; Hartmut Döhner; Gastone Castellani; Gert J. Ossenkoppele; Jesus María Hernández-Rivas; Lars Bullinger; Michael Heuser
err分享
err收藏
Unravelling co-mutational patterns with prognostic implications in NPM1 mutated adult acute myeloid leukemia – a HARMONY study解析具有预后意义的NPM1突变成人急性髓系白血病的共突变模式——一项HARMONY研究
errLeukemia
IF13.4
err2026-01-14
err0
errOAAI
errAlberto Hernández-Sánchez; Ángela Villaverde Ramiro; Eric Sträng; Amin T. Turki; María Abáigar; Jurjen Versluis; Ian Thomas; Marta Sobas; Javier Martínez Elicegui; Gastone Castellani; Axel Benner; Raúl Azibeiro; Jesse M. Tettero; Rabea Mecklenbrauck; Joaquín Martínez-López; Marta Pratcorona; Ken I. Mills; Guillermo Sanz; Maria Teresa Voso; Lehmann Sören; Christoph Röllig; Christian Thiede; Klaus H. Metzeler; Konstanze Döhner; Michael Heuser; Torsten Haferlach; Peter JM Valk; Nigel Russell; Jesús María Hernández-Rivas; Brian Huntly; Gert Ossenkoppele; Hartmut Döhner; Lars Bullinger
err分享
err收藏
Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens通过bulk和single-cell CRISPR筛选鉴定心脏成纤维细胞中纤维化转化的表观遗传调控因子
errNature Communications
IF15.7
err2025-11-26
err0
errOAAI
errLaura Pilar Aguado-Alvaro; Nerea Garitano; Wolfgang Esser-Skala; Judy Sayers; Cynthia del Valle; Daniel Alameda; Julen Mendieta-Esteban; Maria Erendira Calleja-Cervantes; Ainhoa Goñi-Salaverri; Jon Zazpe; Anna Rosaria de Vito; Francesco Marchese; Diego Alignani; Juliana Cudini; Torsten Gross; Gregorio Rábago; Nisha Narayan; Laura Martinez; Sonia Martinez; Brian Huntly; Paul Riley; Arantxa Gonzalez; Jake P. Taylor-King; Nikolaus Fortelny; Beatriz Pelacho; David Lara-Astiaso
err分享
err收藏
Post-transcriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1-mutant AML转录后耗竭核糖体生物发生因子在NPM1突变AML中产生治疗易感性
errBlood
IF23.1
err2025-06-27
err0
errOAAI
errAristi Damaskou; Rachael Wilson; Malgorzata Gozdecka; George Giotopoulos; Ryan Asby; Maria Eleftheriou; Muxin Gu; Christian Récher; Véronique De Mas; Francois Vergez; Ambrine Sahal; Binje Vick; Evangelia K. Papachristou; Ashley Sawle; Eliza Yankova; Monika Dudek; Xiaoxuan Liu; James Russell; Justyna Rak; Christine Hilcenko; Clive D’ Santos; Irmela Jeremias; Jean-Emmanuel Sarry; Konstantinos Tzelepis; Brian J. P. Huntly; Alan J. Warren; Omid Tavana; George S. Vassiliou
err分享
err收藏
Epigenetic Dysregulation in Acute Myeloid Leukemia急性髓系白血病中的表观遗传失调
errSeminars in Hematology
IF4.1
err2025-06-19
err0
errOAAI
errJens Schrezenmeier; B.J.P. Huntly
err分享
err收藏
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibitionCREBBP失活会增强B细胞急性淋巴细胞白血病在BCL2抑制下的铁死亡敏感性。
errNATURE COMMUNICATIONS
IF15.7
err2025-05-20
err0
errOAAI
errGarcia-Gimenez, Alicia; Ditcham, Jonathan E.; Azazi, Dhoyazan M. A.; Giotopoulos, George; Asby, Ryan; Meduri, Eshwar; Bagri, Jaana; Sakakini, Nathalie; Lopez, Cecile K.; Narayan, Nisha; Beinortas, Tumas; Agrawal-Singh, Shuchi; Fung, Kent; O'Connor, David; Mansour, Marc R.; Alabed, Husam B. R.; Jenkins, Benjamin; Koulman, Albert; Murphy, Michael P.; Horton, Sarah J.; Huntly, Brian J. P.
err分享
err收藏
Treatment of acute myeloid leukemia models by targeting a cell surface RNA-binding protein通过靶向细胞表面RNA结合蛋白对急性髓系白血病模型的治疗
errNATURE BIOTECHNOLOGY
IF41.7
err2025-04-23
err0
errOAAI
errGeorge, Benson M.; Eleftheriou, Maria; Yankova, Eliza; Perr, Jonathan; Chai, Peiyuan; Nestola, Gianluca; Almahayni, Karim; Evans, Sian; Damaskou, Aristi; Hemberger, Helena; Lebedenko, Charlotta G.; Rak, Justyna; Yu, Qi; Bapcum, Ece; Russell, James; Bagri, Jaana; Volk, Regan F.; Spiekermann, Malte; Stone, Richard M.; Giotopoulos, George; Huntly, Brian J. P.; Baxter, Joanna; Camargo, Fernando; Liu, Jie; Zaro, Balyn W.; Vassiliou, George S.; Moeckl, Leonhard; de la Rosa, Jorge; Tzelepis, Konstantinos
err分享
err收藏
Timing and trajectory of BCR::ABL1-driven chronic myeloid leukaemiaBCR::ABL1驱动的慢性髓系白血病的发病时间与轨迹
errNATURE
IF48.5
err2025-04-09
err0
errOAAI
errKamizela, Aleksandra E.; Leongamornlert, Daniel; Williams, Nicholas; Wang, Xin; Nyamondo, Kudzai; Dawson, Kevin; Chapman, Michael Spencer; Guo, Jing; Lee, Joe; Mane, Karim; Milne, Kate; Green, Anthony R.; Chevassut, Timothy; Campbell, Peter J.; Ellinor, Patrick T.; Huntly, Brian J. P.; Baxter, E. Joanna; Nangalia, Jyoti
err分享
err收藏
Interim Analysis of Promise, a Clinical Study Combining the BET Inhibitor OPN-2853 with Ruxolitinib in Patients with Advanced Myelofibrosis Experiencing an Inadequate Response to RuxolitinibPromise临床研究中期分析：评估BET抑制剂OPN-2853联合鲁索利替尼治疗对鲁索利替尼应答不足的晚期骨髓纤维化患者的疗效
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errMead, Adam J.; Huntly, Brian J. P.; Psaila, Bethan; Harrison, Claire; Boucher, Rebecca; Wang, Jiayi; Collings, Rebecca; Nagy, Zsofia; Record, Rebecca
err分享
err收藏
Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation急性对BET抑制剂的耐药性通过p300协同激活重塑补偿性转录程序
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errShah, Viral; Giotopoulos, George; Osaki, Hikari; Meyerhoefer, Markus; Meduri, Eshwar; Gallego-Crespo, Aaron; Behrendt, Malte Andreas; Saura-Panella, Maria; Schubert, Benedict; Yun, Haiyang; Horton, Sarah J.; Singh, Shuchi Agrawal; Haehnel, Patricia S.; Basheer, Faisal; Lugo, Dave; Kuehn, Michael; Guezguez, Borhane; Theobald, Matthias; Kindler, Thomas; Gallipoli, Paolo; Yeh, Paul; Dawson, Mark A.; Prinjha, Rab; Huntly, Brian J. P.; Sasca, Daniel
err分享
err收藏
The Prognostic Impact of Myelodysplasia-Related Gene Mutations in Acute Myeloid Leukemia with FLT3-ITD Mutations伴FLT3-ITD突变的急性髓系白血病中，髓系发育不良相关基因突变对预后的影响
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errMecklenbrauck, Rabea; Ramiro, Angela Villaverde; Straeng, Eric; Gabdoulline, Razif; Elicegui, Javier Martinez; Sobas, Marta; Pleyer, Lisa; Voso, Maria Teresa; Benner, Axel; Sanchez, Alberto Hernandez; Tettero, Jesse M.; Tur, Laura; Metzeler, Klaus H.; Onate, Guadalupe; Lehmann, Soren; Huntly, Brian J. P.; Thomas, Ian; Thol, Felicitas R.; Heidel, Florian; Valk, Peter J. M.; Doehner, Konstanze; Haferlach, Torsten; Mills, Ken, I; Doehner, Hartmut; Castellani, Gastone; Ossenkoppele, Gert; Rivas, Jesus Maria Hernandez; Bullinger, Lars; Heuser, Michael
err分享
err收藏
Novel immunotherapeutics against LGR5 to target multiple cancer types (vol 16, pg 2233, 2024)
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-09-25
err1
errOAAI
errChen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M.; Beke, Flavio; Walsh, Stephen J.; Ashman, Nicola; O'Brien, Louise; Fard, Amir Rafati; Ghodsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J.; Hoare, Matthew; Mair, Richard; Serrao, Eva; Brenton, James D.; Garcia-Gimenez, Alicia; Richardson, Simon E.; Huntly, Brian; Spring, David R.; Skjoedt, Mikkel-Ole; Skjodt, Karsten; de la Roche, Marc; de la Roche, Maike
err分享
err收藏
Differential inflammatory conditioning of the bone marrow by acute myeloid leukemia and its impact on progression
errBLOOD ADVANCES
IF7.1
err2024-09-25
err2
errOAAI
errMinciacchi, Valentina R.; Karantanou, Christina; Bravo, Jimena; Pereira, Raquel S.; Zanetti, Costanza; Krack, Theresa; Kumar, Rahul; Bankov, Katrin; Hartmann, Sylvia; Huntly, Brian J. P.; Meduri, Eshwar; Ruf, Wolfram; Krause, Daniela S.
err分享
err收藏
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy
errLEUKEMIA
IF13.4
err2024-09-17
err0
errOAAI
errInnes, Andrew J.; Hayden, Chloe; Orovboni, Victoria; Claudiani, Simone; Fernando, Fiona; Khan, Afzal; Rees, David; Byrne, Jennifer; Gallipoli, Paolo; Francis, Sebastian; Copland, Mhairi; Horne, Gillian; Raghavan, Manoj; Arnold, Claire; Collins, Angela; Cranfield, Tanya; Cunningham, Nicholas; Danga, Akila; Forsyth, Peter; Frewin, Rebecca; Garland, Paula; Hannah, Guy; Avenoso, Daniele; Hassan, Sandra; Huntly, Brian J. P.; Husain, Jissan; Makkuni, Sudhakaran; Rothwell, Kate; Khorashad, Jamshid; Apperley, Jane F.; Milojkovic, Dragana
err分享
err收藏
Novel immunotherapeutics against LGR5 to target multiple cancer types
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-08-21
err1
PREAI
errChen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M.; Beke, Flavio; Walsh, Stephen J.; Ashman, Nicola; O'Brien, Louise; Rafati Fard, Amir; Godsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J.; Hoare, Matthew; Mair, Richard; Serrao, Eva; Brenton, James D.; Garcia-Gimenez, Alicia; Richardson, Simon E.; Huntly, Brian; Spring, David R.; Skjoedt, Mikkel-Ole; Skjodt, Karsten; de la Roche, Marc; de la Roche, Maike
err分享
err收藏
Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study涉及11 q21.3/KMT2A的重排在成人AML中: 突变景观和预后意义-和谐研究
errLEUKEMIA
IF13.4
err2024-07-04
err3
errOAAI
errHernandez-Sanchez, Alberto; Gonzalez, Teresa; Sobas, Marta; Straeng, Eric; Castellani, Gastone; Abaigar, Maria; Valk, Peter J. M.; Ramiro, Angela Villaverde; Benner, Axel; Metzeler, Klaus H.; Azibeiro, Raul; Tettero, Jesse M.; Martinez-Lopez, Joaquin; Pratcorona, Marta; Elicegui, Javier Martinez; Mills, Ken I.; Thiede, Christian; Sanz, Guillermo; Doehner, Konstanze; Heuser, Michael; Haferlach, Torsten; Turki, Amin T.; Reinhardt, Dirk; Schulze-Rath, Renate; Barbus, Martje; Hernandez-Rivas, Jesus Maria; Huntly, Brian; Ossenkoppele, Gert; Doehner, Hartmut; Bullinger, Lars
err分享
err收藏

研究方向

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Michael R. Stratton
H 指数: 179 · 论文数: 644
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H 指数: 159 · 论文数: 749
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Hartmut Döhner
H 指数: 146 · 论文数: 1.4K
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Michael P. Murphy
H 指数: 142 · 论文数: 780
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