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G

George S. Vassiliou

wellcome mrc cambridge stem cell institute
H指数:59
被引数:2.1万

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Pharmacological inhibition of METTL1 as a therapy against solid and blood cancers

METTL1的药理学抑制作为对抗实体瘤和血液癌的疗法

Nature
IF48.5
2026-10-280
OAAI
Eliza Yankova; Alexandra Sapetschnig; Beth Thomas; Siân Evans; Maria Eleftheriou; Malgorzata Gozdecka; Harry Fischl; Teresa Brevini; Rachael Wilson; Sarah J. Bucknell; Andrew Hutchin; Carmen M. Livi; George Giotopoulos; Ryan Asby; Laura Bond; Aleksandra Azevedo; Natalie Webster; Jack Rogan; James Russell; Byron Andrews; Hendrik Weisser; Joanna Baxter; Judith López-Luis; Giovanna Mantica; Jake Tobin; Diego Lopez-Leon; Dean C. Pask; Vidur Tandon; Richard Fosbeary; Sapphire Sawyer; Sunay Usluer; Nithila Joseph; Evangelia Stamou; Maria T. Bejar; Yogeshkumar Malam; Roland Rad; Elisa Laurenti; Juan Li; Maria P. Alcolea; David J. Adams; Walid T. Khaled; Fotios Sampaziotis; George S. Vassiliou; Brian J. P. Huntly; Oliver Rausch; Konstantinos Tzelepis
Transferrin in combination with induction chemotherapy improves outcomes in mouse models of acute myeloid leukemia

转铁蛋白联合诱导化疗可改善急性髓系白血病小鼠模型的预后

Science Translational Medicine
IF14.6
2026-06-240
PRE
Marta Lopes; Filipa Lemos; Lídia Rocha; Carolina Pereira; Catarina Moreira-Barbosa; Joana P. Reis; Tiago L. Duarte; André M. N. Silva; Nuno Gonçalves; Laura Mosteo; Mariana Trigo Miranda; Maria J. Teles; Sérgio Chacim; George S. Vassiliou; Graça Porto; Maria J. Oliveira; Pedro Madureira; Delfim Duarte
The prevalence and clinical significance of clonal monocytosis

克隆性单核细胞增多的患病率及临床意义

Blood
IF23.1
2026-03-100
OA
William G. Dunn; Michael C Sachs; Matteo Maggi; Muxin Gu; Pedro M. Quiros; Kiran Batta; Christen Lykkegaard Andersen; Margarete A. Fabre; Timothy Chevassut; Irina Mohorianu; Daniel H. Wiseman; George S. Vassiliou
A disease model resource reveals core principles of tissue-specific cancer evolution

一个疾病模型资源揭示了组织特异性癌症演化的核心原则

Nature
IF48.5
2026-02-250
OAAI
Sebastian Mueller; Niklas de Andrade Krätzig; Markus Tschurtschenthaler; Miguel G. Silva; Chiara Thordsen; Riccardo Trozzo; Perrine Simon; Frederic Saab; Thorsten Kaltenbacher; Magdalena Zukowska; Daniele Lucarelli; Rupert Öllinger; Joscha Griger; Nina Groß; Tanja Groll; Jessica Löprich; Antonio E. Zaurito; Linus R. Schömig; Jeroen M. Bugter; Stefanie Bärthel; Chiara Falcomatà; Alexander Strong; Cordelia Brandt; Mulham Najajreh; Aristeidis Papargyriou; Roman Maresch; Katharina A. N. Collins; David Sailer; Christian Schneeweis; Sebastian Burger; Lisa M. Fröhlich; Christine Klement; Alexander Belka; Juan J. Montero; Ute Jungwirth; Maximilian Reichert; Markus Moser; Jens Neumann; George Vassiliou; Juan Cadiñanos; Ignacio Varela; Carsten Marr; Daniel F. Alonso; Pier-Luigi Lollini; Jean Zhao; Louis Chesler; Clare M. Isacke; Angela Riedel; Christian J. Braun; Martin L. Sos; Filippo Beleggia; Hans C. Reinhardt; Monica Musteanu; Mariano Barbacid; Michael Quante; Marc Schmidt-Supprian; Günter Schneider; Simon Clare; Trevor D. Lawley; Gordon Dougan; Katja Steiger; Nathalie Conte; Allan Bradley; Lena Rad; Dieter Saur; Roland Rad
CDK7-targeted therapy effectively disrupts cell cycle progression and oncogenic signaling in head and neck cancer

CDK7-targeted疗法可有效破坏头颈癌的细胞周期进程和致癌信号传导

Signal Transduction and Targeted Therapy
IF52.7
2025-11-060
OAAI
María Otero-Rosales; Miguel Álvarez-González; Irene Pazos; Beatriz de Luxán-Delgado; Sonia Del Marro; Esperanza Pozo-Agundo; Mar Rodríguez-Santamaría; Ana López-Fernández; Daniela Corte-Torres; Rocío Granda-Díaz; Saúl Álvarez-Teijeiro; Iván Fernández-Vega; Corina Lorz; Ramón García-Escudero; Juan P. Rodrigo; Konstantinos Tzelepis; George Vassiliou; Irene Ferrer; Mónica Álvarez-Fernández; Juana María García-Pedrero; Francisco Hermida-Prado
Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis

端粒损耗成为衰老造血和白血病发生过程中克隆选择的一种机制。

Nature Genetics
IF0
2025-08-280
OAAI
Matthew A. McLoughlin; Sruthi Cheloor Kovilakam; William G. Dunn; Muxin Gu; Jake Tobin; Yash Pershad; Nicholas Williams; Daniel Leongamornlert; Kevin Dawson; Laura Bond; Ludovica Marando; Sean Wen; Rachael Wilson; Giampiero Valenzano; Vasiliki Symeonidou; Justyna Rak; Aristi Damaskou; Malgorzata Gozdecka; Xiaoxuan Liu; Clea Barcena; Josep Nomdedeu; Paul Costeas; Ioannis D. Dimitriou; Edoardo Fiorillo; Valeria Orrù; Jose Guilherme de Almeida; Thomas McKerrell; Matthew Cullen; Irina Mohorianu; Theodora Foukaneli; Alan J. Warren; Chi Wong; George Follows; Anna L. Godfrey; Emma Gudgin; Francesco Cucca; Eoin McKinney; E. Joanna Baxter; Moritz Gerstung; Jonathan Mitchell; Daniel Wiseman; Alexander G. Bick; Margarete Fabre; Pedro M. Quiros; Jyoti Nangalia; Siddhartha Kar; George S. Vassiliou
Post-transcriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1-mutant AML

转录后耗竭核糖体生物发生因子在NPM1突变AML中产生治疗易感性

Blood
IF23.1
2025-06-270
OA
Aristi Damaskou; Rachael Wilson; Malgorzata Gozdecka; George Giotopoulos; Ryan Asby; Maria Eleftheriou; Muxin Gu; Christian Récher; Véronique De Mas; Francois Vergez; Ambrine Sahal; Binje Vick; Evangelia K. Papachristou; Ashley Sawle; Eliza Yankova; Monika Dudek; Xiaoxuan Liu; James Russell; Justyna Rak; Christine Hilcenko; Clive D’ Santos; Irmela Jeremias; Jean-Emmanuel Sarry; Konstantinos Tzelepis; Brian J. P. Huntly; Alan J. Warren; Omid Tavana; George S. Vassiliou
Treatment of acute myeloid leukemia models by targeting a cell surface RNA-binding protein

通过靶向细胞表面RNA结合蛋白对急性髓系白血病模型的治疗

NATURE BIOTECHNOLOGY
IF41.7
2025-04-230
OA
George, Benson M.; Eleftheriou, Maria; Yankova, Eliza; Perr, Jonathan; Chai, Peiyuan; Nestola, Gianluca; Almahayni, Karim; Evans, Sian; Damaskou, Aristi; Hemberger, Helena; Lebedenko, Charlotta G.; Rak, Justyna; Yu, Qi; Bapcum, Ece; Russell, James; Bagri, Jaana; Volk, Regan F.; Spiekermann, Malte; Stone, Richard M.; Giotopoulos, George; Huntly, Brian J. P.; Baxter, Joanna; Camargo, Fernando; Liu, Jie; Zaro, Balyn W.; Vassiliou, George S.; Moeckl, Leonhard; de la Rosa, Jorge; Tzelepis, Konstantinos
Mutagenic DNA Lesions in Normal Hematopoietic Stem Cells Persist for Years Causing Distinct Patterns of Mutation

正常造血干细胞中的致突变DNA损伤持续数年并导致特异的突变模式

BLOOD
IF23.1
2024-11-050
PRE
Chapman, Michael Spencer; Mitchell, Emily; Yoshida, Kenichi; Williams, Nicholas; Fabre, Margarete A.; Ranzoni, Anna Maria; Robinson, Philip S.; Kregar, Lori; Wilk, C. Matthias; Boettcher, Steffen; Mahbubani, Krishnaa; Saeb-Parsy, Kourosh; Ng, Stanley; Vassiliou, George S.; Gowers, Kate; Janes, Sam; Hoare, Matt; Green, Anthony R.; Cvejic, Ana; Manz, Markus G.; Laurenti, Elisa; Martincorena, Inigo; Stratton, Michael; Nangalia, Jyoti; Coorens, Tim H. H.; Campbell, Peter
SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells
ELIFE
IF0
2024-06-180
OA
Zhang, Linda; Hsu, Joanne, I; Braekeleer, Etienne D.; Chen, Chun-Wei; Patel, Tajhal D.; Martell, Alejandra G.; Guzman, Anna G.; Wohlan, Katharina; Waldvogel, Sarah M.; Uryu, Hidetaka; Tovy, Ayala; Callen, Elsa; Murdaugh, Rebecca L.; Richard, Rosemary; Jansen, Sandra; Vissers, Lisenka; de Vries, Bert B. A.; Nussenzweig, Andre; Huang, Shixia; Coarfa, Cristian; Anastas, Jamie; Takahashi, Koichi; Vassiliou, George; Goodell, Margaret A.
Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma

关于多发性骨髓瘤先兆临床试验优化设计的圆桌讨论

BLOOD CANCER DISCOVERY
IF11.5
2024-05-012
OA
Ghobrial, Irene M.; Gormley, Nicole; Kumar, Shaji K.; Mateos, Maria-Victoria; Bergsagel, P. Leif; Chesi, Marta; Dhodapkar, Madhav V.; Dispenzieri, Angela; Fonseca, Rafael; Getz, Gad; Kastritis, Efstathios; Kristinsson, Sigurdur Y.; Martinez-Climent, Jose Angel; Manier, Salomon; Marinac, Catherine R.; Maura, Francesco; Morgan, Gareth J.; Davies, Faith E.; Nadeem, Omar; Nuvolone, Mario; Paiva, Bruno; O'Donnell, Elizabeth; Prosper, Felipe; Shah, Urvi A.; Sklavenitis-Pistofidis, Romanos; Sperling, Adam S.; Vassiliou, George S.; Munshi, Nikhil C.; Castle, Philip E.; Anderson, Kenneth C.; San Miguel, Jesus F.
Investigating the role of the somatic DDX41 variant in the context of DDX41 hereditary myeloid malignancy syndromes (HMMS)
CANCER RESEARCH
IF16.6
2024-02-010
PRE
Marando, Ludovica; Badar, Talha; Kusne, Yael; Morris, Audrey; Lasho, Terra; Mangaonkar, Abhishek; Finke, Christy; Crawley, Carles; Foran, James M.; Al-Kali, Aref; King, Andrew; Alkhateeb, Hassan; Gangat, Naseema; Wong, Chi; He, Rong; Viswanatha, David; Basheer, Faisal; Litzow, Mark; Ferrer, Alejandro; Vassiliou, George; Patnaik, Mrinal

研究方向

暂未获取到该数据
B
Brian J.P. Huntly
H 指数:64论文数:336被引数:2.3万
R
Roland Rad
H 指数:69论文数:428被引数:2.0万
M
Muxin Gu
H 指数:24论文数:74被引数:3,644
A
Allan Bradley
H 指数:137论文数:461被引数:8.6万
O
Oliver M. Dovey
H 指数:25论文数:57被引数:9,537
M
Mathias Friedrich
H 指数:14论文数:70被引数:1,586
M
Malgorzata Gozdecka
H 指数:13论文数:64被引数:2,964
K
Konstantinos Tzelepis
H 指数:25论文数:99被引数:5,531
C
Carolyn Grove
H 指数:24论文数:84被引数:3,269
I
Ignacio Varela
H 指数:48论文数:153被引数:3.3万