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D

Daniel A. Thomas

University of Strathclyde
H指数:14
被引数:1,489

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Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-12-208
PRE
Wellaway, Christopher R.; Baldwin, Ian R.; Bamborough, Paul; Barker, Daniel; Bartholomew, Michelle A.; Chung, Chun-wa; Dumpelfeld, Birgit; Evans, John P.; Fazakerley, Neal J.; Homes, Paul; Keeling, Steven P.; Lewell, Xiao Q.; McNab, Finlay W.; Morley, Joanne; Needham, Deborah; Neu, Margarete; van Oosterhout, Antoon J. M.; Pal, Anshu; Reinhard, Friedrich B. M.; Rianjongdee, Francesco; Robertson, Craig M.; Rowland, Paul; Shah, Rishi R.; Sherriff, Emma B.; Sloan, Lisa A.; Teague, Simon; Thomas, Daniel A.; Wellaway, Natalie; Wojno-Picon, Justyna; Woolven, James M.; Coe, Diane M.
Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-09-113
PRE
Down, Kenneth; Amour, Augustin; Anderson, Niall A.; Barton, Nick; Campos, Sebastien; Cannons, Edward P.; Clissold, Cole; Convery, Maire A.; Coward, John J.; Doyle, Kevin; Duempelfeld, Birgit; Edwards, Christopher D.; Goldsmith, Michael D.; Krause, Jana; Mallett, David N.; McGonagle, Grant A.; Patel, Vipulkumar K.; Rowedder, James; Rowland, Paul; Sharpe, Andrew; Sriskantharajah, Srividya; Thomas, Daniel A.; Thomson, Douglas W.; Uddin, Sorif; Hamblin, J. Nicole; Hessel, Edith M.
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target

口服可生物利用的PI3Kδ 抑制剂的优化和Vps34作为关键选择性靶标的鉴定

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-12-1919
PREAI
Henley, Zoe A.; Amour, Augustin; Barton, Nick; Bantscheff, Marcus; Bergamini, Giovanna; Bertrand, Sophie M.; Convery, Maire; Down, Kenneth; Duempelfeld, Birgit; Edwards, Chris D.; Grandi, Paola; Gore, Paul M.; Keeling, Steve; Livia, Stefano; Mallett, David; Maxwell, Aoife; Price, Mark; Rau, Christina; Reinhard, Friedrich B. M.; Rowedder, James; Rowland, Paul; Taylor, Jonathan A.; Thomas, Daniel A.; Hessel, Edith M.; Hamblin, J. Nicole
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2015-09-03127
PREAI
Down, Kenneth; Amour, Augustin; Baldwin, Ian R.; Cooper, Anthony W. J.; Deakin, Angela M.; Felton, Leigh M.; Guntrip, Stephen B.; Hardy, Charlotte; Harrison, Zoe A.; Jones, Katherine L.; Jones, Paul; Keeling, Suzanne E.; Le, Joelle; Livia, Stefano; Lucas, Fiona; Lunniss, Christopher J.; Parr, Nigel J.; Robinson, Ed; Rowland, Paul; Smith, Sarah; Thomas, Daniel A.; Vitulli, Giovanni; Washio, Yoshiaki; Hamblin, J. Nicole

研究方向

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J
John P. Evans
H 指数:31论文数:93被引数:3,787
P
Paul Rowland
H 指数:29论文数:113被引数:3,587
M
M.A. Convery
H 指数:26论文数:155被引数:2,163
N
Nigel M. Hooper
H 指数:86论文数:527被引数:3.2万
C
Chun‐wa Chung
H 指数:48论文数:141被引数:1.2万
S
Sébastien Campos
H 指数:13论文数:41被引数:2,061
K
Kenneth Down
H 指数:7论文数:14被引数:465
J
J. Hamblin
H 指数:19论文数:81被引数:1,477
I
Ian R. Baldwin
H 指数:9论文数:20被引数:214
H 指数:0论文数:50被引数:695