Jean‐Paul Vincent - Publications, H-index & Citations

Jean‐Paul Vincent

Francis Crick Institute

46H指数

134论文数

6.7K被引数

收录论文 62

发表时间

HIF-1α-mediated feedback prevents TOR signalling from depleting oxygen supply and triggering stress during normal development HIF-1α介导的反馈可防止TOR信号通路耗尽氧气供应并在正常发育期间引发应激。

Nature Communications

IF15.7

2025-12-21

OAAI

Yifan Zhao; Cyrille Alexandre; Gavin Kelly; Jean-Paul Vincent; Gantas Perez-Mockus

A genetic circuit that extends the useful range of a BMP morphogen arose alongside insect wing evolution 一个扩展BMP形态发生素的适用范围的遗传回路，与昆虫翅膀的进化同时出现。

Current Biology

IF7.5

2025-11-17

OAAI

Anqi Huang; Luca Cocconi; Ben Nicholls-Mindlin; Cyrille Alexandre; Guillaume Salbreux; Jean-Paul Vincent

Signaling-dependent refinement of cell fate choice during tissue remodeling in Drosophila pupal wings 果蝇蛹翅组织重塑期间信号依赖性对细胞命运选择的优化

Developmental Cell

IF8.7

2025-09-18

OAAI

Sophie Herszterg; Simone Cicolini; Marc de Gennes; Anqi Huang; Alexis Matamoro-Vidal; Cyrille Alexandre; Matthew Smith; Helena Araujo; Romain Levayer; Jean-Paul Vincent; Guillaume Salbreux

The Drosophila ecdysone receptor promotes or suppresses proliferation according to ligand level

DEVELOPMENTAL CELL

IF8.7

2023-10-01

OAAI

Perez-Mockus, Gantas; Cocconi, Luca; Alexandre, Cyrille; Aerne, Birgit; Salbreux, Guillaume; Vincent, Jean-Paul

Structural Analysis and Development of Notum Fragment Screening Hits

ACS CHEMICAL NEUROSCIENCE

IF3.9

2022-06-22

OAAI

Zhao, Yuguang; Mahy, William; Willis, Nicky J.; Woodward, Hannah L.; Steadman, David; Bayle, Elliott D.; Atkinson, Benjamin N.; Sipthorp, James; Vecchia, Luca; Ruza, Reinis R.; Harlos, Karl; Jeganathan, Fiona; Constantinou, Stefan; Costa, Artur; Kjaer, Svend; Bictash, Magda; Salinas, Patricia C.; Whiting, Paul; Vincent, Jean-Paul; Fish, Paul, V; Jones, E. Yvonne

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-05-10

OAAI

Willis, Nicky J.; Mahy, William; Sipthorp, James; Zhao, Yuguang; Woodward, Hannah L.; Atkinson, Benjamin N.; Bayle, Elliott D.; Svensson, Fredrik; Frew, Sarah; Jeganathan, Fiona; Monaghan, Amy; Benvegnu, Stefano; Jolly, Sarah; Vecchia, Luca; Ruza, Reinis R.; Kjaer, Svend; Howell, Steven; Snijders, Ambrosius P.; Bictash, Magda; Salinas, Patricia C.; Vincent, Jean-Paul; Jones, E. Yvonne; Whiting, Paul; Fish, Paul, V

Mechanical constraints to cell-cycle progression in a pseudostratified epithelium 假复层上皮细胞周期进展的机械约束

CURRENT BIOLOGY

IF7.5

2022-05-01

OAAI

Hecht, Sophie; Perez-Mockus, Gantas; Schienstock, Dominik; Recasens-Alvarez, Carles; Merino-Aceituno, Sara; Smith, Matt; Salbreux, Guillaume; Degond, Pierre; Vincent, Jean-Paul

Rapid and robust optogenetic control of gene expression in Drosophila

DEVELOPMENTAL CELL

IF8.7

2021-12-01

OAAI

di Pietro, Florencia; Herszterg, Sophie; Huang, Anqi; Bosveld, Floris; Alexandre, Cyrille; Sancere, Lucas; Pelletier, Stephane; Joudat, Amina; Kapoor, Varun; Vincent, Jean-Paul; Bellaiche, Yohanns

Notum deacylates octanoylated ghrelin

MOLECULAR METABOLISM

IF6.6

2021-07-01

OAAI

Zhao, Yuguang; Schuhmacher, Laura-Nadine; Roberts, Morgan; Kakugawa, Satoshi; Bineva-Todd, Ganka; Howell, Steve; O'Reilly, Nicola; Perret, Christine; Snijders, Ambrosius P.; Vincent, Jean-Paul; Jones, E. Yvonne

Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-03-30

OAAI

Bayle, Elliott D.; Svensson, Fredrik; Atkinson, Benjamin N.; Steadman, David; Willis, Nicky J.; Woodward, Hannah L.; Whiting, Paul; Vincent, Jean-Paul; Fish, Paul, V

Generation of extracellular morphogen gradients: the case for diffusion

NATURE REVIEWS GENETICS

IF52

2021-03-25

PREAI

Stapornwongkul, Kristina S.; Vincent, Jean-Paul

Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition

NATURE CELL BIOLOGY

IF19.1

2021-01-25

OAAI

Recasens-Alvarez, Carles; Alexandre, Cyrille; Kirkpatrick, Joanna; Nojima, Hisashi; Huels, David J.; Snijders, Ambrosius P.; Vincent, Jean-Paul

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-10-30

OAAI

Mahy, William; Willis, Nicky J.; Zhao, Yuguang; Woodward, Hannah L.; Svensson, Fredrik; Sipthorp, James; Vecchia, Luca; Ruza, Reinis R.; Hillier, James; Kjaer, Svend; Frew, Sarah; Monaghan, Amy; Bictash, Magda; Salinas, Patricia C.; Whiting, Paul; Vincent, Jean-Paul; Jones, E. Yvonne; Fish, Paul, V

Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands

DEVELOPMENTAL CELL

IF8.7

2020-09-01

OAAI

Yu, Joyce J. S.; Maugarny-Cales, Aude; Pelletier, Stephane; Alexandre, Cyrille; Bellaiche, Yohanns; Vincent, Jean-Paul; McGough, Ian J.

Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells 新型引发剂半胱天冬酶报道子揭示了半胱天冬酶激活细胞的先前未知特征

DEVELOPMENT

IF3.6

2018-12-04

OAAI

Baena-Lopez, Luis Alberto; Arthurton, Lewis; Bischoff, Marcus; Vincent, Jean-Paul; Alexandre, Cyrille; McGregor, Reuben