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L

Lukas Villiger

University of Bern
H指数:17
被引数:3,492

个人简介

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教育背景

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工作经历

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荣誉奖项

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Treatment of a metabolic liver disease in mice with a transient prime editing approach

使用暂时性碱基编辑方法治疗小鼠的代谢性肝病

NATURE BIOMEDICAL ENGINEERING
IF26.6
2025-05-200
OA
Rothgangl, Tanja; Talas, Andras; Ioannidi, Eleonora I.; Weber, Yanik; Bock, Desiree; Matsushita, Mai; Villiger, Elina Andrea; Schmidheini, Lukas; Moon, Woohyun J.; Lin, Paulo J. C.; Fan, Steven H. Y.; Marquart, Kim F.; Schwerdel, Cornelia; Rimann, Nicole; Faccin, Erica; Villiger, Lukas; Muramatsu, Hiromi; Vadovics, Mate; Cremonesi, Alessio; Kulcsar, Peter Istvan; Thoeny, Beat; Kopf, Manfred; Haberle, Johannes; Pardi, Norbert; Tam, Ying K.; Schwank, Gerald
Reprogramming site-specific retrotransposon activity to new DNA sites

将位点特异性逆转座子活性重编程至新的DNA位点

NATURE
IF48.5
2025-04-091
PRE
Fell, Christopher W.; Villiger, Lukas; Lim, Justin; Hiraizumi, Masahiro; Tagliaferri, Dario; Yarnall, Matthew T. N.; Lee, Anderson; Jiang, Kaiyi; Kayabolen, Alisan; Krajeski, Rohan N.; Schmitt-Ulms, Cian; Ramani, Harsh; Yousef, Sarah M.; Roberts, Nathaniel; Vakulskas, Christopher A.; Nishimasu, Hiroshi; Abudayyeh, Omar O.; Gootenberg, Jonathan S.
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

使用CRISPR指导的整合酶在没有双链DNA切割的情况下拖放大序列的基因组插入

NATURE BIOTECHNOLOGY
IF41.7
2022-11-24197
OA
Yarnall, Matthew T. N.; Ioannidi, Eleonora I.; Schmitt-Ulms, Cian; Krajeski, Rohan N.; Lim, Justin; Villiger, Lukas; Zhou, Wenyuan; Jiang, Kaiyi; Garushyants, Sofya K.; Roberts, Nathaniel; Zhang, Liyang; Vakulskas, Christopher A.; Walker, John A. I. I. I. I.; Kadina, Anastasia P.; Zepeda, Adrianna E.; Holden, Kevin; Ma, Hong; Xie, Jun; Gao, Guangping; Foquet, Lander; Bial, Greg; Donnelly, Sara K.; Miyata, Yoshinari; Radiloff, Daniel R.; Henderson, Jordana M.; Ujita, Andrew; Abudayyeh, Omar O.; Gootenberg, Jonathan S.
Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy
CELL GENOMICS
IF9
2022-02-0131
OAAI
Hirt, Christian K.; Booij, Tijmen H.; Grob, Linda; Simmler, Patrik; Toussaint, Nora C.; Keller, David; Taube, Doreen; Ludwig, Vanessa; Goryachkin, Alexander; Pauli, Chantal; Lenggenhager, Daniela; Stekhoven, Daniel J.; Stirnimann, Christian U.; Endhardt, Katharina; Ringnalda, Femke; Villiger, Lukas; Siebenhuner, Alexander; Karkampouna, Sofia; De Menna, Marta; Beshay, Janette; Klett, Hagen; Julio, Marianna Kruithof-de; Schuler, Julia; Schwank, Gerald
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

猕猴体内PCSK9的腺嘌呤碱基编辑可降低LDL胆固醇水平

NATURE BIOTECHNOLOGY
IF41.7
2021-05-19246
OAAI
Rothgangl, Tanja; Dennis, Melissa K.; Lin, Paulo J. C.; Oka, Rurika; Witzigmann, Dominik; Villiger, Lukas; Qi, Weihong; Hruzova, Martina; Kissling, Lucas; Lenggenhager, Daniela; Borrelli, Costanza; Egli, Sabina; Frey, Nina; Bakker, Noelle; Walker, John A., II; Kadina, Anastasia P.; Victorov, Denis V.; Pacesa, Martin; Kreutzer, Susanne; Kontarakis, Zacharias; Moor, Andreas; Jinek, Martin; Weissman, Drew; Stoffel, Markus; van Boxtel, Ruben; Holden, Kevin; Pardi, Norbert; Thoeny, Beat; Haeberle, Johannes; Tam, Ying K.; Semple, Sean C.; Schwank, Gerald
Elevated HbA1c is not associated with recurrent venous thromboembolism in the elderly, but with all-cause mortality- the SWEETCO 65+study
SCIENTIFIC REPORTS
IF3.9
2020-02-125
OAAI
Mathis, Alexandra; Villiger, Lukas; Reiner, Martin F.; Egloff, Michael; Schmid, Hans Ruedi; Stivala, Simona; Limacher, Andreas; Mean, Marie; Aujesky, Drahomir; Rodondi, Nicolas; Angelillo-Scherrer, Anna; Righini, Marc; Staub, Daniel; Aschwanden, Markus; Frauchiger, Beat; Osterwalder, Joseph; Kucher, Nils; Matter, Christian M.; Banyai, Martin; Hugli, Oliver; Beer, Juerg H.
Growth of Epithelial Organoids in a Defined Hydrogel

定义的水凝胶中上皮类器官的生长

ADVANCED MATERIALS
IF26.8
2018-09-10211
OAAI
Broguiere, Nicolas; Isenmann, Luca; Hirt, Christian; Ringel, Till; Placzek, Silja; Cavalli, Emma; Ringnalda, Femke; Villiger, Lukas; Zuellig, Richard; Lehmann, Roger; Rogler, Gerhard; Heim, Markus H.; Schueler, Julia; Zenobi-Wong, Marcy; Schwank, Gerald

研究方向

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G
Gerald Schwank
H 指数:33论文数:85被引数:8,445
J
Jonathan S. Gootenberg
H 指数:49论文数:121被引数:4.3万
O
Omar O. Abudayyeh
H 指数:46论文数:115被引数:3.7万
T
Tanja Rothgangl
H 指数:10论文数:25被引数:843
F
Femke Ringnalda
H 指数:15论文数:35被引数:2,910
K
Kaiyi Jiang
H 指数:13论文数:25被引数:1,038
K
Kim Fabiano Marquart
H 指数:12论文数:29被引数:585
L
Lukas Schmidheini
H 指数:9论文数:19被引数:527
S
Sharan Janjuha
H 指数:12论文数:28被引数:1,258
Y
Ying K. Tam
H 指数:62论文数:188被引数:2.0万