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Phase I study of bevacizumab and temsirolimus combination therapy in advanced malignancies: safety, efficacy, and ovarian cancer expansion 贝伐珠单抗和替西罗莫司联合疗法在晚期恶性肿瘤中的I期研究：安全性、有效性和卵巢癌扩展 Piha-Paul, Sarina A.; Tseng, Chieh; Thompson, Emily; Stafford, R. Jason; Le, Hung; Kang, Lei; Fu, Siqing; Tsimberidou, Apostolia; Blumenschein, George; Ahnert, Jordi Rodon; Slopis, John M.; Hong, David; Naing, Aung; Meric-Bernstam, Funda; Ng, Chaan S.; Westin, Shannon; Sood, Anil K. 分享 收藏
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A First-In-Human Study of the SUMOylation Inhibitor Subasumstat in Patients with Advanced/Metastatic Solid Tumors or Relapsed/Refractory Hematologic Malignancies Juric, Dejan; Anderson, Daniel; Dowlati, Afshin; Rodon, Jordi; Lugowska, Iwona; Mandziuk, Slawomir; Song, Yuqin; Woei-A-Jin, Feng Jung Sherida H.; Andre, Marc; Tybor, Joanna Gora; Hernandez-Rivas, Jose-Angel; Kurzrock, Razelle; Lopez-Guillermo, Armando; Schroder, David; Stec, Rafal; Berger, Allison; Chao, Bo; Chudnovsky, Aleksander; Gibbs, John P.; Long, Tao; Stroopinsky, Dina; Dong, Qi; Olszanski, Anthony J. 分享 收藏
Pemigatinib for previously treated metastatic or unresectable central nervous system tumors with fibroblast growth factor receptor mutations or rearrangements: FIGHT-207 results 培米加替尼用于既往治疗过的具有成纤维细胞生长因子受体突变或重排的转移性或不可切除的中枢神经系统肿瘤：FIGHT-207研究结果 Spanggaard, Iben; Matrana, Marc; Rocha Lima, Caio; Mahipal, Amit; Vieito, Maria; Hervieu, Alice; Goyal, Lipika; Rodon, Jordi; Veronese, Maria Luisa; Oliveira, Natalia; Li, Xin; Schaffer, Michael; Kesari, Santosh 分享 收藏
A PHASE 1/2 TRIAL OF FOG-001, A FIRST-IN-CLASS DIRECT β-CATENIN:TCF4 INHIBITOR: SAFETY AND PRELIMINARY ANTITUMOR ACTIVITY IN ADAMANTINOMATOUS CRANIOPHARYNGIOMA (ACP) PATIENTS I期/II期FOG-001试验：一种首创的、直接作用于β-CATENIN:TCF4的抑制剂，在成釉细胞瘤性颅咽管瘤（ACP）患者中的安全性及初步抗肿瘤活性研究 Papadopoulos, Kyriakos P.; Brastianos, Priscilla K.; Cecchini, Michael; Khushman, Moh'd; Kummar, Shivaani; Pelster, Meredith; Rodon, Jordi; Sharma, Sunil; Yaeger, Rona; Rojo, Jonathan; Wells, Amber L.; Tipps, Megan; Berry, Wade; Garofalo, Amanda; Akella, Lalith; Yu, Ziyang; Ramos, Jorge D.; Nguyen, Marie Huong; Orford, Keith; Klempner, Samuel J. 分享 收藏
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Afatinib in patients with solid tumors with neuregulin 1 (NRG1) fusions: a case series from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study 阿法替尼在具有神经营养因子1（NRG1）融合的实体瘤患者中的应用：Targeted Agent and Profiling Utilization Registry（TAPUR）研究中的病例系列 Rodon, J.; Rothe, M.; Mangat, P. K.; Garrett-Mayer, E.; Cannon, T. L.; Hobbs, E.; Kalemkerian, G. P.; Hinshaw, D. C.; Gregory, A.; Grantham, G. N.; Halabi, S.; Schilsky, R. L. 分享 收藏
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Sacituzumab tirumotecan in advanced non-small-cell lung cancer with or without EGFR mutations: phase 1/2 and phase 2 trials Sacituzumab tirumotecan在有无EGFR突变晚期非小细胞肺癌中的研究：Ⅰ/Ⅱ期和Ⅱ期临床试验 Zhao, Shen; Cheng, Ying; Wang, Qiming; Li, Xingya; Liao, Jun; Rodon, Jordi; Meng, Xiangjiao; Luo, Yongzhong; Chen, Zhendong; Wang, Wei; Yi, Tienan; Li, Yongsheng; Yin, Yongmei; Xu, Huiting; Yu, Guohua; Mi, Yanjun; Fan, Yun; Wainberg, Zev A.; Wang, Xiang; Su, Cuiyun; Yu, Qitao; Lai, Shuzhen; Sun, Longhua; Zhuang, Wu; Wang, Xian; Yang, Jiacheng; Li, Yaling; Ge, Junyou; Li, Jin; Zhang, Li 分享 收藏
A phase I/II trial of avelumab combinations with ivuxolimab, utomilumab, and radiation therapy in patients with advanced gastrointestinal malignancies 一项avelumab联合ivuxolimab、utomilumab和放射治疗的I/II期临床试验，用于治疗晚期胃肠道恶性肿瘤患者 Ahmed, Jibran; Knisely, Anne; Torrado, Carlos; Stephen, Bettzy; Yang, Yali; Song, Juhee; Alshawa, Anas; Zarifa, Abdulrazzak; Jhingran, Anuja; Koay, Eugene J.; Morris, Van Karlyle; Javle, Milind; Wolff, Robert A.; Meric-Bernstam, Funda; Pant, Shubham; Rodon, Jordi; Naing, Aung 分享 收藏
Olaparib in treatment-refractory isocitrate dehydrogenase 1 (IDH1)- and IDH2-mutant cholangiocarcinoma: Safety and antitumor activity from the phase 2 National Cancer Institute 10129 trial 奥拉帕尼治疗难治性异柠檬酸脱氢酶1 (IDH1) 和IDH2-mutant胆管癌: 来自美国国家癌症研究所10129期2试验的安全性和抗肿瘤活性 Cecchini, Michael; Pilat, Mary Jo; Uboha, Nataliya; Azad, Nilofer S.; Cho, May; Davis, Elizabeth J.; Ahnert, Jordi Rodon; Tinoco, Gabriel; Shapiro, Geoffrey I.; Khagi, Simon; Powers, Benjamin; Spencer, Kristen; Groisberg, Roman; Drappatz, Jan; Chen, Li; Das, Biswajit; Bao, Xun; Li, Jing; Narayan, Azeet; Vu, Dennis; Patel, Abhijit; Niger, Monica; Doroshow, Deborah; Durecki, Diane; Boerner, Scott A.; Bindra, Ranjit; Ivy, Percy; Shyr, Derek; Shyr, Yu; Lorusso, Patricia M. 分享 收藏
Phase I trial of the combination of the pan-ErbB inhibitor neratinib and mTOR inhibitor everolimus in advanced cancer patients with ErbB family gene alterations Piha-Paul, S. A.; Tseng, C.; Tran, H. T.; Naing, A.; Dumbrava, E. E.; Karp, D. D.; Rodon, J.; Yap, T. A.; Raghav, K. P.; Damodaran, S.; Le, X.; Soliman, P. T.; Lim, J.; Meric-Bernstam, F. 分享 收藏
First-in-human study of AMG 193, an MTA-cooperative PRMT5 inhibitor, in patients with MTAP-deleted solid tumors: results from phase I dose exploration5 MTAP缺失的实体瘤患者中MTA合作PRMT5抑制剂AMG 193的首次人体研究: I期剂量探索的结果5 Rodon, J.; Prenen, H.; Sacher, A.; Villalona-Calero, M.; Penel, N.; El Helali, A.; Rottey, S.; Yamamoto, N.; Ghiringhelli, F.; Goebeler, M. E.; Doi, T.; Postel-Vinay, S.; Lin, C. -c.; Liu, C.; Chuang, C. -h.; Keyvanjah, K.; Eggert, T.; Neil, B. h. o ' 分享 收藏
The ESMO Tumour-Agnostic Classifier and Screener (ETAC-S): a tool for assessing tumour-agnostic potential of molecularly guided therapies and for steering drug development ESMO肿瘤不可知分类器和筛选器 (etac-s): 一种评估分子引导疗法的肿瘤不可知潜力和指导药物开发的工具 Westphalen, C. B.; Martins-Branco, D.; Beal, J. R.; Cardone, C.; Coleman, N.; Schram, A. M.; Halabi, S.; Michiels, S.; Yap, C.; Andre, F.; Bibeau, F.; Curigliano, G.; Garralda, E.; Kummar, S.; Kurzrock, R.; Limaye, S.; Loges, S.; Marabelle, A.; Marchio, C.; Mateo, J.; Rodon, J.; Spanic, T.; Pentheroudakis, G.; Subbiah, V. 分享 收藏
First results of a Phase 1 study evaluating safety, PK, PD and clinical activity of STC-15, aMETTL3 inhibitor, in patients with advanced malignancies Rodon, J.; Moser, J. C.; Papadopoulos, K. P.; Ofir-Rosenfeld, Y.; Weisser, H.; Snyder, M.; Schmalbach, T.; Barker, T.; Deshpande, D.; Skead, B.; Hester, D.; Sheth, N.; Leon, P. Saldana; Blanco-Cepeda, E.; Rausch, O.; Holz, J. B. 分享 收藏
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