logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
T

Thomas Kuilman

Utrecht University Medical Center
H指数:21
被引数:9,418

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies

基于从诊断性肿瘤活检样本高通量TCR发现，实现下一代工程化TCR-T疗法

NATURE COMMUNICATIONS
IF15.7
2025-01-140
OA
Kuilman, Thomas; Schrikkema, Deborah S.; Gadiot, Jules; Gomez-Eerland, Raquel; Bies, Laura; Walker, Julia; Spaapen, Robbert M.; Kok, Hanna; Houg, Demi; Viyacheva, Milena; Claassen, Yvonne B.; Saornil, Manuel; Krijgsman, Oscar; Stringer, Bas; Ding, Huiwen; Geleijnse, Anou; Meinema, Anne C.; Weissbrich, Bianca; Lancee, Melissa; Engele, Carmen G.; Sabatino, Marianna; Chen, Pei-Ling; Tsai, Kenneth Y.; Mule, James J.; Sondak, Vernon K.; van den Bulk, Jitske; de Miranda, Noel F.; Jedema, Inge; Haanen, John G.; van Heijst, Jeroen W. J.; Schumacher, Ton N.; Linnemann, Carsten; Bendle, Gavin M.
An adverse tumor-protective effect of IDO1 inhibition

IDO1抑制的不良肿瘤保护作用

CELL REPORTS MEDICINE
IF10.6
2023-02-0110
OAAI
Kenski, Juliana C. N.; Huang, Xinyao; Vredevoogd, David W.; de Bruijn, Beaunelle; Traets, Joleen J. H.; Ibanez-Molero, Sofia; Schieven, Sebastiaan M.; van Vliet, Alex; Krijgsman, Oscar; Kuilman, Thomas; Pozniak, Joanna; Loayza-Puch, Fabricio; Terry, Alexandra M.; Mueller, Judith; Logtenberg, Meike E. W.; de Bruijn, Marjolein; Levy, Pierre; Korner, Pierre-Rene; Goding, Colin R.; Schumacher, Ton N.; Marine, Jean-Christophe; Agami, Reuven; Peeper, Daniel S.
SERPINB9 is commonly amplified and high expression in cancer cells correlates with poor immune checkpoint blockade response

SERPINB9通常被扩增，癌细胞中的高表达与免疫检查点阻断反应差相关

ONCOIMMUNOLOGY
IF6.3
2022-11-2916
OA
Ibanez-Molero, Sofia; van Vliet, Alex; Pozniak, Joanna; Hummelink, Karlijn; Terry, Alexandra M.; Monkhorst, Kim; Sanders, Joyce; Hofland, Ingrid; Landeloos, Ewout; Van Herck, Yannick; Bechter, Oliver; Kuilman, Thomas; Zhong, Weiwei; Marine, Jean-Christophe; Wessels, Lodewyk; Peeper, Daniel S.
Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4
CLINICAL CANCER RESEARCH
IF10.2
2021-07-061
OA
Krijgsman, Oscar; Kemper, Kristel; Boshuizen, Julia; Vredevoogd, David W.; Rozeman, Elisa A.; Molero, Sofia Ibanez; de Bruijn, Beaunelle; Cornelissen-Steijger, Paulien; Shahrabi, Aida; Velasco-Herrera, Martin Del Castillo; Song, Ji-Ying; Ligtenberg, Maarten A.; Kluin, Roelof J. C.; Kuilman, Thomas; Ross-Macdonald, Petra; Haanen, John B. A. G.; Adams, David J.; Blank, Christian U.; Peeper, Daniel S.
Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors
NATURE MEDICINE
IF50
2018-01-15188
PREAI
Boshuizen, Julia; Koopman, Louise A.; Krijgsman, Oscar; Shahrabi, Aida; Gresnigt-van den Heuvel, Elke; Ligtenberg, Maarten A.; Vredevoogd, David W.; Kemper, Kristel; Kuilman, Thomas; Song, Ji-Ying; Pencheva, Nora; Mortensen, Jens Thing; Foppen, Marnix Geukes; Rozeman, Elisa A.; Blank, Christian U.; Janmaat, Maarten L.; Satijn, David; Breij, Esther C. W.; Peeper, Daniel S.; Parren, Paul W. H. I.
Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients
CELL REPORTS
IF6.9
2016-07-01123
OAAI
Semenova, Ekaterina A.; Kwon, Min-chul; Monkhorst, Kim; Song, Ji-Ying; Bhaskaran, Rajith; Krijgsman, Oscar; Kuilman, Thomas; Peters, Dennis; Buikhuisen, Wieneke A.; Smit, Egbert F.; Pritchard, Colin; Cozijnsen, Miranda; van der Vliet, Jan; Zevenhoven, John; Lambooij, Jan-Paul; Proost, Natalie; van Montfort, Erwin; Velds, Arno; Huijbers, Ivo J.; Berns, Anton
BRAFV600E Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts
CELL REPORTS
IF6.9
2016-06-0184
OAAI
Kemper, Kristel; Krijgsman, Oscar; Kong, Xiangjun; Cornelissen-Steijger, Paulien; Shahrabi, Aida; Weeber, Fleur; van der Velden, Daphne L.; Bleijerveld, Onno B.; Kuilman, Thomas; Kluin, Roel J. C.; Sun, Chong; Voest, Emile E.; Ju, Young Seok; Schumacher, Ton N. M.; Altelaar, A. F. Maarten; McDermott, Ultan; Adams, David J.; Blank, Christian U.; Haanen, John B.; Peeper, Daniel S.
Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

从人类结直肠癌转移灶活检培养的类器官中保留的遗传多样性

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2015-10-12386
OAAI
Weeber, Fleur; van de Wetering, Marc; Hoogstraat, Marlous; Dijkstra, Krijn K.; Krijgsman, Oscar; Kuilman, Thomas; Gadellaa-van Hooijdonk, Christa G. M.; van der Velden, Daphne L.; Peeper, Daniel S.; Cuppen, Edwin P. J. G.; Vries, Robert G.; Clevers, Hans; Voest, Emile E.
Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

跨不同数据集和平台重复的样本拷贝数谱的鲁棒BRCA1-like分类

MOLECULAR ONCOLOGY
IF4.5
2015-03-2027
OAAI
Schouten, Philip C.; Grigoriadis, Anita; Kuilman, Thomas; Mirza, Hasan; Watkins, Johnathan A.; Cooke, Saskia A.; van Dyk, Ewald; Severson, Tesa M.; Rueda, Oscar M.; Hoogstraat, Marlous; Verhagen, Caroline V. M.; Natrajan, Rachael; Chin, Suet-Feung; Lips, Esther H.; Kruizinga, Janneke; Velds, Arno; Nieuwland, Marja; Kerkhoven, Ron M.; Krijgsman, Oscar; Vens, Conchita; Peeper, Daniel; Nederlof, Petra M.; Caldas, Carlos; Tutt, Andrew N.; Wessels, Lodewyk F.; Linn, Sabine C.
CopywriteR: DNA copy number detection from off-target sequence data
GENOME BIOLOGY
IF9.4
2015-02-27173
OAAI
Kuilman, Thomas; Velds, Arno; Kemper, Kristel; Ranzani, Marco; Bombardelli, Lorenzo; Hoogstraat, Marlous; Nevedomskaya, Ekaterina; Xu, Guotai; de Ruiter, Julian; Lolkema, Martijn P.; Ylstra, Bauke; Jonkers, Jos; Rottenberg, Sven; Wessels, Lodewyk F.; Adams, David J.; Peeper, Daniel S.; Krijgsman, Oscar
Detailed imaging and genetic analysis reveal a secondary BRAFL505H resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib
PIGMENT CELL & MELANOMA RESEARCH
IF2.6
2015-01-073
PREAI
Hoogstraat, Marlous; Gadellaa-van Hooijdonk, Christa G.; Ubink, Inge; Besselink, Nicolle J. M.; Pieterse, Mark; Veldhuis, Wouter; van Stralen, Marijn; Meijer, Eelco F. J.; Willems, Stefan M.; Hadders, Michael A.; Kuilman, Thomas; Krijgsman, Oscar; Peeper, Daniel S.; Koudijs, Marco J.; Cuppen, Edwin; Voest, Emile E.; Lolkema, Martijn P.

研究方向

暂未获取到该数据
D
Daniel S. Peeper
H 指数:62论文数:299被引数:2.7万
O
Oscar Krijgsman
H 指数:34论文数:173被引数:5,576
E
Emile E. Voest
H 指数:92论文数:811被引数:3.8万
D
David W. Vredevoogd
H 指数:15论文数:52被引数:1,245
J
Ji‐Ying Song
H 指数:49论文数:303被引数:8,522
K
Kristel Kemper
H 指数:28论文数:112被引数:7,286
D
David J. Adams
H 指数:113论文数:975被引数:5.7万
T
Ton N. Schumacher
H 指数:109论文数:733被引数:8.3万
A
Arno Velds
H 指数:32论文数:127被引数:9,276
M
Marlous Hoogstraat
H 指数:22论文数:120被引数:4,549