logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
O

Oscar Krijgsman

agendia
H指数:34
被引数:5,563

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies

基于从诊断性肿瘤活检样本高通量TCR发现，实现下一代工程化TCR-T疗法

NATURE COMMUNICATIONS
IF15.7
2025-01-140
OA
Kuilman, Thomas; Schrikkema, Deborah S.; Gadiot, Jules; Gomez-Eerland, Raquel; Bies, Laura; Walker, Julia; Spaapen, Robbert M.; Kok, Hanna; Houg, Demi; Viyacheva, Milena; Claassen, Yvonne B.; Saornil, Manuel; Krijgsman, Oscar; Stringer, Bas; Ding, Huiwen; Geleijnse, Anou; Meinema, Anne C.; Weissbrich, Bianca; Lancee, Melissa; Engele, Carmen G.; Sabatino, Marianna; Chen, Pei-Ling; Tsai, Kenneth Y.; Mule, James J.; Sondak, Vernon K.; van den Bulk, Jitske; de Miranda, Noel F.; Jedema, Inge; Haanen, John G.; van Heijst, Jeroen W. J.; Schumacher, Ton N.; Linnemann, Carsten; Bendle, Gavin M.
A Dysfunctional T-cell Gene Signature for Predicting Nonresponse to PD-1 Blockade in Non-small Cell Lung Cancer That Is Suitable for Routine Clinical Diagnostics

用于预测非小细胞肺癌对PD-1阻断无反应的功能失调的T细胞基因签名，适用于常规临床诊断

CLINICAL CANCER RESEARCH
IF10.2
2023-12-134
OAAI
Hummelink, Karlijn; Tissier, Renaud; Bosch, Linda J. W.; Krijgsman, Oscar; van den Heuvel, Michel M.; Theelen, Willemijn S. M. E.; Damotte, Diane; Goldwasser, Francois; Leroy, Karen; Smit, Egbert F.; Meijer, Gerrit A.; Thommen, Daniela S.; Monkhorst, Kim
An adverse tumor-protective effect of IDO1 inhibition

IDO1抑制的不良肿瘤保护作用

CELL REPORTS MEDICINE
IF10.6
2023-02-0110
OAAI
Kenski, Juliana C. N.; Huang, Xinyao; Vredevoogd, David W.; de Bruijn, Beaunelle; Traets, Joleen J. H.; Ibanez-Molero, Sofia; Schieven, Sebastiaan M.; van Vliet, Alex; Krijgsman, Oscar; Kuilman, Thomas; Pozniak, Joanna; Loayza-Puch, Fabricio; Terry, Alexandra M.; Mueller, Judith; Logtenberg, Meike E. W.; de Bruijn, Marjolein; Levy, Pierre; Korner, Pierre-Rene; Goding, Colin R.; Schumacher, Ton N.; Marine, Jean-Christophe; Agami, Reuven; Peeper, Daniel S.
Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling
NATURE COMMUNICATIONS
IF15.7
2022-04-0830
OAAI
Apriamashvili, Georgi; Vredevoogd, David W.; Krijgsman, Oscar; Bleijerveld, Onno B.; Ligtenberg, Maarten A.; de Bruijn, Beaunelle; Boshuizen, Julia; Traets, Joleen J. H.; Altimari, Daniela D'Empaire; van Vliet, Alex; Lin, Chun-Pu; Visser, Nils L.; Londino, James D.; Sanchez-Hodge, Rebekah; Oswalt, Leah E.; Altinok, Selin; Schisler, Jonathan C.; Altelaar, Maarten; Peeper, Daniel S.
Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma
NATURE COMMUNICATIONS
IF15.7
2021-12-22151
OAAI
Vos, Joris L.; Elbers, Joris B. W.; Krijgsman, Oscar; Traets, Joleen J. H.; Qiao, Xiaohang; van der Leun, Anne M.; Lubeck, Yoni; Seignette, Iris M.; Smit, Laura A.; Willems, Stefan M.; van den Brekel, Michiel W. M.; Dirven, Richard; Karakullukcu, M. Baris; Karssemakers, Luc; Klop, W. Martin C.; Lohuis, Peter J. F. M.; Schreuder, Willem H.; Smeele, Ludi E.; van der Velden, Lilly-Ann; Tan, I. Bing; Onderwater, Suzanne; Jasperse, Bas; Vogel, Wouter V.; Al-Mamgani, Abrahim; Keijser, Astrid; van der Noort, Vincent; Broeks, Annegien; Hooijberg, Erik; Peeper, Daniel S.; Schumacher, Ton N.; Blank, Christian U.; de Boer, Jan Paul; Haanen, John B. A. G.; Zuur, Charlotte L.
Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
CANCER DISCOVERY
IF33.3
2021-12-2037
OA
Song, Kai; Minami, Jenna K.; Huang, Arthur; Dehkordi, Siavash R.; Lomeli, Shirley H.; Luebeck, Jens; Goodman, Mark H.; Moriceau, Gatien; Krijgsman, Oscar; Dharanipragada, Prashanthi; Ridgley, Trevor; Crosson, William P.; Salazar, Jesus; Pazol, Eli; Karin, Gabriel; Jayaraman, Rachana; Balanis, Nikolas G.; Alhani, Salwan; Sheu, Kyle; Ten Hoeve, Johanna; Palermo, Amelia; Motika, Stephen E.; Senaratne, T. Niroshi; Paraiso, Kim H.; Hergenrother, Paul J.; Rao, P. Nagesh; Multani, Asha S.; Peeper, Daniel S.; Bafna, Vineet; Lo, Roger S.; Graeber, Thomas G.
High CD8+ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy

高CD8肿瘤浸润淋巴细胞密度与对新辅助放化疗反应不良的食管腺癌预后不良相关

HISTOPATHOLOGY
IF4.1
2021-04-276
PREAI
Koemans, Willem J.; van Dieren, Jolanda M.; van den Berg, Jose G.; Meijer, Gerrit A.; Snaebjornsson, Petur; Chalabi, Myriam; Lecot, Frederig; Riedl, Robert; Krijgsman, Oscar; Hofland, Ingrid; Broeks, Annegien; Voncken, Francine E. M.; Peppelenbosch, Maikel P.; Sosef, Meindert N.; van Sandick, Johanna W.; Kodach, Liudmila L.
Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma
NATURE MEDICINE
IF50
2021-02-08218
PREAI
Rozeman, E. A.; Hoefsmit, E. P.; Reijers, I. L. M.; Saw, R. P. M.; Versluis, J. M.; Krijgsman, O.; Dimitriadis, P.; Sikorska, K.; van de Wiel, B. A.; Eriksson, H.; Gonzalez, M.; Torres Acosta, A.; Grijpink-Ongering, L. G.; Shannon, K.; Haanen, J. B. A. G.; Stretch, J.; Ch'ng, S.; Nieweg, O. E.; Mallo, H. A.; Adriaansz, S.; Kerkhoven, R. M.; Cornelissen, S.; Broeks, A.; Klop, W. M. C.; Zuur, C. L.; van Houdt, W. J.; Peeper, D. S.; Spillane, A. J.; van Akkooi, A. C. J.; Scolyer, R. A.; Schumacher, T. N. M.; Menzies, A. M.; Long, G. V.; Blank, C. U.
Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade
CANCER RESEARCH
IF16.6
2021-02-0237
OA
Boshuizen, Julia; Pencheva, Nora; Krijgsman, Oscar; Altimari, Daniela D'Empaire; Castro, Patricia Garrido; de Bruijn, Beaunelle; Ligtenberg, Maarten A.; Gresnigt-Van den Heuvel, Elke; Vredevoogd, David W.; Song, Ji-Ying; Visser, Nils; Apriamashvili, Georgi; Janmaat, Maarten L.; Plantinga, Theo S.; Franken, Patrick; Houtkamp, Mischa; Lingnau, Andreas; Jure-Kunkel, Maria; Peeper, Daniel S.
PERSONALIZED COMBINATION OF NEOADJUVANT DOMATINOSTAT, NIVOLUMAB (NIVO) AND IPILIMUMAB (IPI) IN MACROSCOPIC STAGE III MELANOMA PATIENTS STRATIFIED ACCORDING TO INTERFERON-GAMMA (IFN-GAMMA) SIGNATURE - THE DONIMI STUDY
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2020-10-013
OAAI
Reijers, I. L. M.; Rozeman, E. A.; Dimitriadis, P.; Krijgsman, O.; Bosch, L. J. W.; Cornelissen, S.; Bouwman, J.; Versluis, J. M.; Rao, D.; van de Wiel, B.; Spillane, A. J.; Scolyer, R. A.; Menzies, A. M.; van Akkooi, A. C. J.; Long, G. V.; Blank, C. U.
36-months and 18-months relapse-free survival after (neo)adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma patients - update of the OpACIN and OpACIN-neo trials
CANCER RESEARCH
IF16.6
2020-08-158
PRE
Blank, Christian U.; Versluis, Judith M.; Rozeman, Elisa A.; Menzies, Alexander M.; Reijers, Irene L.; Krijgsman, Oscar; Hoefsmit, Esmee P.; van de Wiel, Bart A.; Sikorska, Karolina; Bierman, Carolien; Dimitriadis, Petros; Gonzalez, Maria; Broeks, Annegien; Kerkhoven, Ron M.; Spillane, Andrew J.; Haanen, John B.; van Houdt, Winan J.; Saw, Robyn P.; Eriksson, Hanna; van Akkooi, Alexander C.; Scolyer, Richard A.; Schumacher, Ton N.; Long, Georgina, V
Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
NATURE COMMUNICATIONS
IF15.7
2020-08-0772
OAAI
Boshuizen, Julia; Vredevoogd, David W.; Krijgsman, Oscar; Ligtenberg, Maarten A.; Blankenstein, Stephanie; de Bruijn, Beaunelle; Frederick, Dennie T.; Kenski, Juliana C. N.; Parren, Mara; Bruggemann, Marieke; Madu, Max F.; Rozeman, Elisa A.; Song, Ji-Ying; Horlings, Hugo M.; Blank, Christian U.; van Akkooi, Alexander C. J.; Flaherty, Keith T.; Boland, Genevieve M.; Peeper, Daniel S.
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
CELL REPORTS
IF6.9
2019-10-01228
OAAI
Renner, Kathrin; Bruss, Christina; Schnell, Annette; Koehl, Gudrun; Becker, Holger M.; Fante, Matthias; Menevse, Ayse-Nur; Kauer, Nathalie; Blazquez, Raquel; Hacker, Lisa; Decking, Sonja-Maria; Bohn, Toszka; Faerber, Stephanie; Evert, Katja; Aigle, Lisa; Amslinger, Sabine; Landa, Maria; Krijgsman, Oscar; Rozeman, Elisa A.; Brummer, Christina; Siska, Peter J.; Singer, Katrin; Pektor, Stefanie; Miederer, Matthias; Peter, Katrin; Gottfried, Eva; Herr, Wolfgang; Marchiq, Ibtisam; Pouyssegur, Jacques; Roush, William R.; Ong, SuFey; Warren, Sarah; Pukrop, Tobias; Beckhove, Philipp; Lang, Sven A.; Bopp, Tobias; Blank, Christian U.; Cleveland, John L.; Oefner, Peter J.; Dettmer, Katja; Selby, Mark; Kreutz, Marina
Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities
NATURE CELL BIOLOGY
IF19.1
2019-06-0331
OAAI
Coppe, Jean-Philippe; Mori, Miki; Pan, Bo; Yau, Christina; Wolf, Denise M.; Ruiz-Saenz, Ana; Brunen, Diede; Prahallad, Anirudh; Cornelissen-Steijger, Paulien; Kemper, Kristel; Posch, Christian; Wang, Changjun; Dreyer, Courtney A.; Krijgsman, Oscar; Lee, Pei Rong Evelyn; Chen, Zhongzhong; Peeper, Daniel S.; Moasser, Mark M.; Bernards, Rene; van't Veer, Laura J.

研究方向

暂未获取到该数据
D
Daniel S. Peeper
H 指数:62论文数:299被引数:2.7万
T
Thomas Kuilman
H 指数:21论文数:97被引数:9,412
C
Christian U. Blank
H 指数:95论文数:670被引数:5.8万
G
Gerrit A. Meijer
H 指数:89论文数:1,107被引数:3.4万
K
Kristel Kemper
H 指数:28论文数:112被引数:7,281
B
Bauke Ylstra
H 指数:69论文数:574被引数:2.1万
T
Ton N. Schumacher
H 指数:109论文数:733被引数:8.3万
J
Ji‐Ying Song
H 指数:49论文数:303被引数:8,513
J
John B.A.G. Haanen
H 指数:109论文数:931被引数:9.8万
D
David J. Adams
H 指数:113论文数:975被引数:5.7万