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H

Hening Lin

university of chicago

62H指数
330论文数
1.8W被引数
收录论文 132
发表时间
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Development of GS-441524 Derivatives as Potent SARS-CoV-2 Mac1 Inhibitors via a Direct-to-Biology Approach通过直接生物学方法开发GS-441524衍生物作为强效SARS-CoV-2 Mac1抑制剂
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-08-28
err0
PREAI
errKewen Peng; Suryadeep Chakraborty; Shamar D. Wallace; Jessica Caroline Gomes Noll; Jialin Shang; Xuan Lu; Annette Choi; Gary Whittaker; J. Christopher Fromme; Hening Lin
err分享
err收藏
Trans-regulatory gene mapping prioritizes disease drivers in asthma跨调控基因作图优先识别哮喘疾病驱动因素
errCell
IF42.5
err2026-08-11
err0
errOAAI
errIsabella M. Salamone; Peixin Tian; Zining Qi; Jiaqi Zhao; Li Zhang; Qilong Tan; Jinghui Li; Ashley N. Michael; Alexis G. Thornburg; Noboru J. Sakabe; Mark Minogue; Zachary T. Weber; Bohao Chen; Cezary Ciszewski; Xin He; Hardik Shah; Donata Vercelli; Carole Ober; Hening Lin; Zhonghua Liu
err分享
err收藏
ACSS2 is required for colorectal cancer progression and a druggable target for colorectal cancer treatmentACSS2是结直肠癌进展所必需的，也是结直肠癌治疗的可成药靶点
erriScience
IF4.1
err2026-07-21
err0
errOAAI
errLei Wang; Urszula Dougherty; Wenliang He; Lu Gao; Caleb Muefong; Rajesh Sarkar; Jie Du; Ardaman Shergill; Hening Lin; Marc Bissonnette; Yan Chun Li
err分享
err收藏
A ratiometric fluorescent reporter of mitochondrial sodium线粒体钠离子的比率荧光报告分子
errNature Chemical Biology
IF13.7
err2026-06-22
err0
PREAI
errKoushambi Mitra; Soyoung Kim; Daphne Oettinger; Sanjeev Uthishtran; Qian Zhao; Aneesh Tazhe Veetil; Joseph R. Ramirez; Hening Lin; Senthil Arumugam; Yamuna Krishnan
err分享
err收藏
NEK7 Cys298 is important for NLRP3 inflammasome and targetable by dimethyl fumarateNEK7 Cys298对NLRP3炎性小体至关重要且可被二甲基富马酸靶向
errCell Chemical Biology
IF7.2
err2026-04-21
err0
errOAAI
errYandong Zhang; Helena Lindner; Brian So; Zirong Chen; Haoyang Li; Jiashu Xu; Jiahe Wang; Jie Xu; Alexandru M. Petre; Mark D. Distefano; Gabriel Núñez; Hening Lin
err分享
err收藏
A High-Throughput Fluorescence Polarization Assay for Screening Sirtuin Inhibitors高通量荧光偏振分析用于筛选去乙酰化酶抑制剂
errACS Chemical Biology
IF3.8
err2026-04-17
err0
PREAI
errKewen Peng; Suryadeep Chakraborty; Yizhen Jin; Hening Lin
err分享
err收藏
HDAC5 regulates the activation of cytotoxic CD8+T cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBorregard, Megan; Ciszewski, Cezary; Zhang, Yandong; Lin, Hening; Jabri, Bana
err分享
err收藏
Biochemistry and regulation of histone lysine l-lactylation组蛋白赖氨酸乳酰化的生物化学及其调控
errNature Reviews Molecular Cell Biology
IF90.2
err2025-08-19
err0
PREAI
errXinlei Sheng; Hening Lin; Philip A. Cole; Yingming Zhao
err分享
err收藏
PARP7 inhibition stabilizes STAT1/STAT2 and relieves experimental autoimmune encephalomyelitis in micePARP7抑制稳定STAT1/STAT2并缓解小鼠实验性自身免疫性脑脊髓炎
errCell Reports
IF6.9
err2025-08-12
err0
errOAAI
errJiashu Xu; Tao Yu; Zongwei Yue; Xuan Lu; Yandong Zhang; Lei Wang; Samaneh Shabani Åhrling; Michael R. Smith; Yan Chun Li; Jason Matthews; Hening Lin
err分享
err收藏
Myristoylation of TMEM106B by NMT1/2 regulates TMEM106B trafficking and turnoverTMEM106B经NMT1/2的豆蔻酰化调控其运输和周转
errJournal of Biological Chemistry
IF3.9
err2025-07-01
err0
errOAAI
errAlexander Lacrampe; Dan Hou; Isis G. Perez; Belvin Gong; Natalia Franco-Hernandez; Angie Yee; Wenzhe Chen; Maxime Ah Young-Chapon; Hening Lin; Fenghua Hu
err分享
err收藏
Antibiotic target discovery by integrated phenotypic and activity-based profiling of electrophilic fragments通过整合电亲核片段的表型与基于活性的分析进行抗生素靶点发现
errCELL CHEMICAL BIOLOGY
IF7.2
err2025-02-01
err0
errOAAI
errJin, Yizhen; Jana, Sadhan; Abbasov, Mikail E.; Lin, Hening
err分享
err收藏
Loss of Diphthamide Increases DNA Replication Stress in Mammalian Cells by Modulating the Translation of RRM1
errACS CENTRAL SCIENCE
IF10.4
err2024-09-06
err0
errOAAI
errZhao, Jiaqi; Ahn, Byunghyun; Lin, Hening
err分享
err收藏
A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-27
err1
errOAAI
errJana, Sadhan; Shang, Jialin; Hong, Jun Young; Fenwick, Michael K.; Puri, Rishi; Lu, Xuan; Melnick, Ari M.; Li, Meng; Lin, Hening
err分享
err收藏
MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunityMAVS Cys508棕榈酰化促进其在线粒体外膜上的聚集和抗病毒先天免疫
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-08-14
err0
errOAAI
errLiu, Yinong; Hou, Dan; Chen, Wenzhe; Lu, Xuan; Komaniecki, Garrison P.; Xu, Yilai; Yu, Tao; Zhang, Sophia M.; Linder, Maurine E.; Lin, Hening
err分享
err收藏
GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains
errACS CHEMICAL BIOLOGY
IF3.8
err2024-04-22
err1
errOAAI
errPeng, Kewen; Wallace, Shamar D.; Bagde, Saket R.; Shang, Jialin; Anmangandla, Ananya; Jana, Sadhan; Fromme, J. Christopher; Lin, Hening
err分享
err收藏
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-04-22
err3
errOAAI
errHou, Dan; Yu, Tao; Lu, Xuan; Hong, Jun Young; Yang, Min; Zi, Yanlin; Ho, Thanh Tu; Lin, Hening
err分享
err收藏
NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
errCELL REPORTS
IF6.9
err2024-04-01
err8
errOAAI
errYu, Tao; Hou, Dan; Zhao, Jiaqi; Lu, Xuan; Greentree, Wendy K.; Zhao, Qian; Yang, Min; Conde, Don-Gerard; Linder, Maurine E.; Lin, Hening
err分享
err收藏
A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain (vol 18, pg 1200, 2023)
errACS CHEMICAL BIOLOGY
IF3.8
err2024-03-27
err0
errOAAI
errAnmangandla, Ananya; Jana, Sadhan; Peng, Kewen; Wallace, Shamar D.; Bagde, Saket R.; Drown, Bryon S.; Xu, Jiashu; Hergenrother, Paul J.; Fromme, J. Christopher; Lin, Hening
err分享
err收藏
HDAC11's de-fatty acylation of SF3B2 could provide new understanding of RNA splicing regulation and Liver Cancer progression
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errClements, Jenna; Peng, Changmin; Thanh Tu Ho; Lin, Hening; Seto, Edward
err分享
err收藏
Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets
errNATURE REVIEWS CANCER
IF66.8
err2024-02-29
err7
PREAI
errTate, Edward W.; Soday, Lior; de la Lastra, Ana Losada; Wang, Mei; Lin, Hening
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
J
Johan Auwerx
H 指数: 183 · 论文数: 913
C
Christopher T. Walsh
H 指数: 144 · 论文数: 852
R
Rudolph E. Tanzi
H 指数: 143 · 论文数: 836
D
David R. Liu
H 指数: 124 · 论文数: 379
杨
杨敏 (Min Yang)
H 指数: 121 · 论文数: 3.6K
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