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S

Sandra B. Gabelli

Sidney Kimmel Comprehensive Cancer Center
H指数:40
被引数:7,767

个人简介

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教育背景

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工作经历

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荣誉奖项

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Bispecific antibodies and CAR T cells targeting a TP53 mutation-associated neoantigen show discordant affinity requirements

双特异性抗体和靶向TP53突变相关新抗原的CAR T细胞显示出不同的亲和力需求

Journal of Clinical Investigation
IF13.6
2026-01-160
OA
Dinapoli, Sarah R.; Wright, Katharine M.; Mog, Brian J.; Pearlman, Alexander H.; Nichakawade, Tushar D.; Marcou, Nikita; Hsiue, Emily Han-Chung; Hwang, Michael S.; Douglass, Jacqueline; Liu, Qiang; Watson, Evangeline; Dal Molin, Marco; Cohen, Joshua D.; Popoli, Maria; Paul, Suman; Konig, Maximilian F.; Wyhs, Nicolas; Azurmendi, P. Aitana; Glavaris, Stephanie; Ge, Jiaxin; Awosika, Tolulope O.; Liu, Jin; Gabrielson, Kathleen L.; Gabelli, Sandra B.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Zhou, Shibin; Vogelstein, Bert
WRN structural flexibility showcased through fragment-based lead discovery of inhibitors

WRN结构柔韧性通过基于片段的先导化合物发现抑制剂得到展示

Nature Communications
IF15.7
2026-01-030
OAAI
Rachel L. Palte; Mihir Mandal; Justyna Sikorska; Artjohn B. Villafania; Meredith M. Rickard; Robert J. Bauer; Alexei V. Buevich; Xiaomei Chai; Jiafang He; Zahid Hussain; Markus Koglin; Hannah B. MacDonald; My S. Mansueto; Klaus Maskos; Joey L. Methot; Jaclyn Robustelli; Aileen Soriano; Marcel J. Tauchert; Sriram Tyagarajan; Minjia Zhang; Daniel J. Klein; Jacqueline D. Hicks; David G. McLaren; Sandra B. Gabelli; Daniel F. Wyss
Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-07-101
PRE
Mog, Brian J.; Marcou, Nikita; Dinapoli, Sarah R.; Pearlman, Alexander H.; Nichakawade, Tushar D.; Hwang, Michael S.; Douglass, Jacqueline; Hsiue, Emily Han-Chung; Glavaris, Stephanie; Wright, Katharine M.; Konig, Maximilian F.; Paul, Suman; Wyhs, Nicolas; Ge, Jiaxin; Miller, Michelle S.; Azurmendi, Aitana; Watson, Evangeline; Pardoll, Drew M.; Gabelli, Sandra B.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin
Cancer therapy with antibodies

用抗体治疗癌症

NATURE REVIEWS CANCER
IF66.8
2024-05-1314
PRE
Paul, Suman; Konig, Maximilian F.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Wright, Katharine M.; Gabelli, Sandra B.; Ho, Mitchell; van Elsas, Andrea; Zhou, Shibin
TRBC1-targeting antibody–drug conjugates for the treatment of T cell cancers

用于治疗T细胞癌症的TRBC1-targeting抗体-药物结合物

Nature
IF48.5
2024-03-270
PRE
Tushar D. Nichakawade; Jiaxin Ge; Brian J. Mog; Bum Seok Lee; Alexander H. Pearlman; Michael S. Hwang; Sarah R. DiNapoli; Nicolas Wyhs; Nikita Marcou; Stephanie Glavaris; Maximilian F. Konig; Sandra B. Gabelli; Evangeline Watson; Cole Sterling; Nina Wagner-Johnston; Sima Rozati; Lode Swinnen; Ephraim Fuchs; Drew M. Pardoll; Kathy Gabrielson; Nickolas Papadopoulos; Chetan Bettegowda; Kenneth W. Kinzler; Shibin Zhou; Surojit Sur; Bert Vogelstein; Suman Paul
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen

疏水相互作用主导了KRAS G12V新抗原的识别

NATURE COMMUNICATIONS
IF15.7
2023-08-218
OAAI
Wright, Katharine M.; DiNapoli, Sarah R.; Miller, Michelle S.; Azurmendi, P. Aitana; Zhao, Xiaowei; Yu, Zhiheng; Chakrabarti, Mayukh; Shi, WuXian; Douglass, Jacqueline; Hwang, Michael S.; Hsiue, Emily Han-Chung; Mog, Brian J.; Pearlman, Alexander H.; Paul, Suman; Konig, Maximilian F.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.
Hybrid TCR-CAR design surpasses conventional CARs and patient-derived TCRs in targeting an ultra-low-density neoantigen
CANCER RESEARCH
IF16.6
2023-04-140
PRE
Mog, Brian J.; DiNapoli, Sarah R.; Hwang, Michael S.; Nichakawade, Tushar D.; Douglass, Jacqueline; Hsiue, Emily Han-Chung; Wright, Katharine M.; Pearlman, Alexander H.; Konig, Maximilian F.; Paul, Suman; Wyhs, Nicolas; Marcou, Nikita; Glavaris, Stephanie; Ge, Jiaxin; Miller, Michelle S.; Azurmendi, P. Aitana; Watson, Evangeline; Pardoll, Drew M.; Gabelli, Sandra B.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin
The rapid and highly parallel identification of antibodies with defined biological activities by SLISY

通过slissy快速，高度平行地鉴定具有确定生物学活性的抗体

NATURE COMMUNICATIONS
IF15.7
2023-01-031
OAAI
Lu, Steve; Mattox, Austin K.; Azurmendi, P. Aitana; Christodoulou, Ilias; Wright, Katharine M.; Popoli, Maria; Chen, Zan; Sur, Surojit; Li, Yana; Bonifant, Challice L.; Bettegowda, Chetan; Papadopoulos, Nickolas; Zhou, Shibin; Gabelli, Sandra B.; Vogelstein, Bert; Kinzler, Kenneth W.

研究方向

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L
L. Mario Amzel
H 指数:0论文数:0被引数:0
B
Bert Vogelstein
H 指数:255论文数:1,043被引数:36.8万
K
Kenneth W. Kinzler
H 指数:213论文数:786被引数:24.8万
S
Shibin Zhou
H 指数:49论文数:158被引数:4.0万
K
Katharine M. Wright
H 指数:13论文数:29被引数:1,012
J
Jacqueline Douglass
H 指数:16论文数:69被引数:1,796
C
Chetan Bettegowda
H 指数:69论文数:751被引数:3.1万
N
Nickolas Papadopoulos
H 指数:101论文数:530被引数:9.1万
M
Michelle S. Miller
H 指数:17论文数:56被引数:1,370
S
Suman Paul
H 指数:20论文数:100被引数:2,024