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S

Shibin Zhou

Johns Hopkins University School of Medicine
H指数:49
被引数:4.0万

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TRBC2-targeting antibody–drug conjugates for the treatment of T cell cancers

用于治疗T细胞癌症的TRBC2-targeting抗体-药物结合物

Nature Cancer
IF28.5
2025-12-220
PRE
Jiaxin Ge; Joshua Urban; Sarah R. DiNapoli; Bum Seok Lee; Taha Ahmedna; Tushar D. Nichakawade; Brian J. Mog; Steve Lu; Xuyang Li; Nikita Marcou; Stephanie Glavaris; Jacqueline Douglass; Jin Liu; Maximilian F. Konig; Evangeline Watson; Maria Popoli; J. David Peske; Sima Rozati; Cole H. Sterling; Nina Wagner-Johnston; Richard F. Ambinder; Kathy Gabrielson; Charles G. Mullighan; Nickolas Papadopoulos; Chetan Bettegowda; Drew M. Pardoll; Shibin Zhou; Surojit Sur; Kenneth W. Kinzler; Bert Vogelstein; Suman Paul
Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-07-101
PRE
Mog, Brian J.; Marcou, Nikita; Dinapoli, Sarah R.; Pearlman, Alexander H.; Nichakawade, Tushar D.; Hwang, Michael S.; Douglass, Jacqueline; Hsiue, Emily Han-Chung; Glavaris, Stephanie; Wright, Katharine M.; Konig, Maximilian F.; Paul, Suman; Wyhs, Nicolas; Ge, Jiaxin; Miller, Michelle S.; Azurmendi, Aitana; Watson, Evangeline; Pardoll, Drew M.; Gabelli, Sandra B.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin
Cancer therapy with antibodies

用抗体治疗癌症

NATURE REVIEWS CANCER
IF66.8
2024-05-1314
PRE
Paul, Suman; Konig, Maximilian F.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Wright, Katharine M.; Gabelli, Sandra B.; Ho, Mitchell; van Elsas, Andrea; Zhou, Shibin
TRBC1-targeting antibody–drug conjugates for the treatment of T cell cancers

用于治疗T细胞癌症的TRBC1-targeting抗体-药物结合物

Nature
IF48.5
2024-03-270
PRE
Tushar D. Nichakawade; Jiaxin Ge; Brian J. Mog; Bum Seok Lee; Alexander H. Pearlman; Michael S. Hwang; Sarah R. DiNapoli; Nicolas Wyhs; Nikita Marcou; Stephanie Glavaris; Maximilian F. Konig; Sandra B. Gabelli; Evangeline Watson; Cole Sterling; Nina Wagner-Johnston; Sima Rozati; Lode Swinnen; Ephraim Fuchs; Drew M. Pardoll; Kathy Gabrielson; Nickolas Papadopoulos; Chetan Bettegowda; Kenneth W. Kinzler; Shibin Zhou; Surojit Sur; Bert Vogelstein; Suman Paul
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen

疏水相互作用主导了KRAS G12V新抗原的识别

NATURE COMMUNICATIONS
IF15.7
2023-08-218
OAAI
Wright, Katharine M.; DiNapoli, Sarah R.; Miller, Michelle S.; Azurmendi, P. Aitana; Zhao, Xiaowei; Yu, Zhiheng; Chakrabarti, Mayukh; Shi, WuXian; Douglass, Jacqueline; Hwang, Michael S.; Hsiue, Emily Han-Chung; Mog, Brian J.; Pearlman, Alexander H.; Paul, Suman; Konig, Maximilian F.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.
Hybrid TCR-CAR design surpasses conventional CARs and patient-derived TCRs in targeting an ultra-low-density neoantigen
CANCER RESEARCH
IF16.6
2023-04-140
PRE
Mog, Brian J.; DiNapoli, Sarah R.; Hwang, Michael S.; Nichakawade, Tushar D.; Douglass, Jacqueline; Hsiue, Emily Han-Chung; Wright, Katharine M.; Pearlman, Alexander H.; Konig, Maximilian F.; Paul, Suman; Wyhs, Nicolas; Marcou, Nikita; Glavaris, Stephanie; Ge, Jiaxin; Miller, Michelle S.; Azurmendi, P. Aitana; Watson, Evangeline; Pardoll, Drew M.; Gabelli, Sandra B.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin
The rapid and highly parallel identification of antibodies with defined biological activities by SLISY

通过slissy快速，高度平行地鉴定具有确定生物学活性的抗体

NATURE COMMUNICATIONS
IF15.7
2023-01-031
OAAI
Lu, Steve; Mattox, Austin K.; Azurmendi, P. Aitana; Christodoulou, Ilias; Wright, Katharine M.; Popoli, Maria; Chen, Zan; Sur, Surojit; Li, Yana; Bonifant, Challice L.; Bettegowda, Chetan; Papadopoulos, Nickolas; Zhou, Shibin; Gabelli, Sandra B.; Vogelstein, Bert; Kinzler, Kenneth W.
TCR-mimic bispecific antibodies to target the HIV-1 reservoir

TCR模拟双特异性抗体靶向HIV-1库

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-04-0816
OAAI
Sengupta, Srona; Board, Nathan L.; Wu, Fengting; Moskovljevic, Milica; Douglass, Jacqueline; Zhang, Josephine; Reinhold, Bruce R.; Duke-Cohan, Jonathan; Yu, Jeanna; Reed, Madison C.; Tabdili, Yasmine; Azurmendi, Aitana; Fray, Emily J.; Zhang, Hao; Hsiue, Emily Han-Chung; Jenike, Katharine; Ho, Ya-Chi; Gabelli, Sandra B.; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin; Siliciano, Janet D.; Sadegh-Nasseri, Scheherazade; L.Reinherz, Ellis; Siliciano, Robert F.
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens

靶向HLA限制性新抗原的嵌合抗原受体的结构工程

NATURE COMMUNICATIONS
IF15.7
2021-09-0625
OAAI
Hwang, Michael S.; Miller, Michelle S.; Thirawatananond, Puchong; Douglass, Jacqueline; Wright, Katharine M.; Hsiue, Emily Han-Chung; Mog, Brian J.; Aytenfisu, Tihitina Y.; Murphy, Michael B.; Azurmendi, P. Aitana; Skora, Andrew D.; Pearlman, Alexander H.; Paul, Suman; DiNapoli, Sarah R.; Konig, Maximilian F.; Bettegowda, Chetan; Pardoll, Drew M.; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.
Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers

anti-PD-1-treated肺癌中新抗原特异性TIL的转录程序

Nature
IF48.5
2021-07-210
OAAI
Justina X. Caushi; Jiajia Zhang; Zhicheng Ji; Ajay Vaghasia; Boyang Zhang; Emily Han-Chung Hsiue; Brian J. Mog; Wenpin Hou; Sune Justesen; Richard Blosser; Ada Tam; Valsamo Anagnostou; Tricia R. Cottrell; Haidan Guo; Hok Yee Chan; Dipika Singh; Sampriti Thapa; Arbor G. Dykema; Poromendro Burman; Begum Choudhury; Luis Aparicio; Laurene S. Cheung; Mara Lanis; Zineb Belcaid; Margueritta El Asmar; Peter B. Illei; Rulin Wang; Jennifer Meyers; Kornel Schuebel; Anuj Gupta; Alyza Skaist; Sarah Wheelan; Jarushka Naidoo; Kristen A. Marrone; Malcolm Brock; Jinny Ha; Errol L. Bush; Bernard J. Park; Matthew Bott; David R. Jones; Joshua E. Reuss; Victor E. Velculescu; Jamie E. Chaft; Kenneth W. Kinzler; Shibin Zhou; Bert Vogelstein; Janis M. Taube; Matthew D. Hellmann; Julie R. Brahmer; Taha Merghoub; Patrick M. Forde; Srinivasan Yegnasubramanian; Hongkai Ji; Drew M. Pardoll; Kellie N. Smith
Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection
ELIFE
IF0
2021-06-1118
OA
Koenecke, Allison; Powell, Michael; Xiong, Ruoxuan; Shen, Zhu; Fischer, Nicole; Huq, Sakibul; Khalafallah, Adham M.; Trevisan, Marco; Sparen, Par; Carrero, Juan J.; Nishimura, Akihiko; Caffo, Brian; Stuart, Elizabeth A.; Bai, Renyuan; Staedtke, Verena; Thomas, David L.; Papadopoulos, Nickolas; Kinzler, Ken W.; Vogelstein, Bert; Zhou, Shibin; Bettegowda, Chetan; Konig, Maximilian F.; Mensh, Brett D.; Vogelstein, Joshua T.; Athey, Susan
Targeting public neoantigens for cancer immunotherapy
NATURE CANCER
IF28.5
2021-05-1793
OAAI
Pearlman, Alexander H.; Hwang, Michael S.; Konig, Maximilian F.; Hsiue, Emily Han-Chung; Douglass, Jacqueline; DiNapoli, Sarah R.; Mog, Brian J.; Bettegowda, Chetan; Pardoll, Drew M.; Gabelli, Sandra B.; Papadopoulos, Nicholas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin
Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-05-1761
OA
Dykema, Arbor G.; Zhang, Boyang; Woldemeskel, Bezawit A.; Garliss, Caroline C.; Cheung, Laurene S.; Choudhury, Dilshad; Zhang, Jiajia; Aparicio, Luis; Bom, Sadhana; Rashid, Rufiaat; Caushi, Justina X.; Hsiue, Emily Han-Chung; Cascino, Katherine; Thompson, Elizabeth A.; Kwaa, Abena K.; Singh, Dipika; Thapa, Sampriti; Ordonez, Alvaro A.; Pekosz, Andrew; D'Alessio, Franco R.; Powell, Jonathan D.; Yegnasubramanian, Srinivasan; Zhou, Shibin; Pardoll, Drew M.; Ji, Hongkai; Cox, Andrea L.; Blankson, Joel N.; Smith, Kellie N.

研究方向

暂未获取到该数据
B
Bert Vogelstein
H 指数:255论文数:1,043被引数:36.8万
K
Kenneth W. Kinzler
H 指数:213论文数:786被引数:24.8万
C
Chetan Bettegowda
H 指数:69论文数:751被引数:3.1万
N
Nickolas Papadopoulos
H 指数:101论文数:530被引数:9.1万
S
Sandra B. Gabelli
H 指数:40论文数:234被引数:7,767
J
Jacqueline Douglass
H 指数:16论文数:69被引数:1,796
M
Maximilian F. Konig
H 指数:31论文数:120被引数:3,882
D
Drew M. Pardoll
H 指数:164论文数:893被引数:16.5万
B
Brian J. Mog
H 指数:13论文数:68被引数:1,634
E
Emily Han-Chung Hsiue
H 指数:19论文数:83被引数:1,924