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K

Katharine M. Wright

Johns Hopkins Medicine
H指数:13
被引数:1,012

个人简介

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教育背景

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工作经历

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荣誉奖项

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Bispecific antibodies and CAR T cells targeting a TP53 mutation-associated neoantigen show discordant affinity requirements

双特异性抗体和靶向TP53突变相关新抗原的CAR T细胞显示出不同的亲和力需求

Journal of Clinical Investigation
IF13.6
2026-01-160
OA
Dinapoli, Sarah R.; Wright, Katharine M.; Mog, Brian J.; Pearlman, Alexander H.; Nichakawade, Tushar D.; Marcou, Nikita; Hsiue, Emily Han-Chung; Hwang, Michael S.; Douglass, Jacqueline; Liu, Qiang; Watson, Evangeline; Dal Molin, Marco; Cohen, Joshua D.; Popoli, Maria; Paul, Suman; Konig, Maximilian F.; Wyhs, Nicolas; Azurmendi, P. Aitana; Glavaris, Stephanie; Ge, Jiaxin; Awosika, Tolulope O.; Liu, Jin; Gabrielson, Kathleen L.; Gabelli, Sandra B.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Zhou, Shibin; Vogelstein, Bert
Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-07-101
PRE
Mog, Brian J.; Marcou, Nikita; Dinapoli, Sarah R.; Pearlman, Alexander H.; Nichakawade, Tushar D.; Hwang, Michael S.; Douglass, Jacqueline; Hsiue, Emily Han-Chung; Glavaris, Stephanie; Wright, Katharine M.; Konig, Maximilian F.; Paul, Suman; Wyhs, Nicolas; Ge, Jiaxin; Miller, Michelle S.; Azurmendi, Aitana; Watson, Evangeline; Pardoll, Drew M.; Gabelli, Sandra B.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin
Cancer therapy with antibodies

用抗体治疗癌症

NATURE REVIEWS CANCER
IF66.8
2024-05-1314
PRE
Paul, Suman; Konig, Maximilian F.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Wright, Katharine M.; Gabelli, Sandra B.; Ho, Mitchell; van Elsas, Andrea; Zhou, Shibin
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen

疏水相互作用主导了KRAS G12V新抗原的识别

NATURE COMMUNICATIONS
IF15.7
2023-08-218
OAAI
Wright, Katharine M.; DiNapoli, Sarah R.; Miller, Michelle S.; Azurmendi, P. Aitana; Zhao, Xiaowei; Yu, Zhiheng; Chakrabarti, Mayukh; Shi, WuXian; Douglass, Jacqueline; Hwang, Michael S.; Hsiue, Emily Han-Chung; Mog, Brian J.; Pearlman, Alexander H.; Paul, Suman; Konig, Maximilian F.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.
Hybrid TCR-CAR design surpasses conventional CARs and patient-derived TCRs in targeting an ultra-low-density neoantigen
CANCER RESEARCH
IF16.6
2023-04-140
PRE
Mog, Brian J.; DiNapoli, Sarah R.; Hwang, Michael S.; Nichakawade, Tushar D.; Douglass, Jacqueline; Hsiue, Emily Han-Chung; Wright, Katharine M.; Pearlman, Alexander H.; Konig, Maximilian F.; Paul, Suman; Wyhs, Nicolas; Marcou, Nikita; Glavaris, Stephanie; Ge, Jiaxin; Miller, Michelle S.; Azurmendi, P. Aitana; Watson, Evangeline; Pardoll, Drew M.; Gabelli, Sandra B.; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin
The rapid and highly parallel identification of antibodies with defined biological activities by SLISY

通过slissy快速，高度平行地鉴定具有确定生物学活性的抗体

NATURE COMMUNICATIONS
IF15.7
2023-01-031
OAAI
Lu, Steve; Mattox, Austin K.; Azurmendi, P. Aitana; Christodoulou, Ilias; Wright, Katharine M.; Popoli, Maria; Chen, Zan; Sur, Surojit; Li, Yana; Bonifant, Challice L.; Bettegowda, Chetan; Papadopoulos, Nickolas; Zhou, Shibin; Gabelli, Sandra B.; Vogelstein, Bert; Kinzler, Kenneth W.
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens

靶向HLA限制性新抗原的嵌合抗原受体的结构工程

NATURE COMMUNICATIONS
IF15.7
2021-09-0625
OAAI
Hwang, Michael S.; Miller, Michelle S.; Thirawatananond, Puchong; Douglass, Jacqueline; Wright, Katharine M.; Hsiue, Emily Han-Chung; Mog, Brian J.; Aytenfisu, Tihitina Y.; Murphy, Michael B.; Azurmendi, P. Aitana; Skora, Andrew D.; Pearlman, Alexander H.; Paul, Suman; DiNapoli, Sarah R.; Konig, Maximilian F.; Bettegowda, Chetan; Pardoll, Drew M.; Papadopoulos, Nickolas; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.
TCR β chain-directed bispecific antibodies for the treatment of T cell cancers
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-03-1040
OA
Paul, Suman; Pearlman, Alexander H.; Douglass, Jacqueline; Mog, Brian J.; Hsiue, Emily Han-Chung; Hwang, Michael S.; DiNapoli, Sarah R.; Konig, Maximilian F.; Brown, Patrick A.; Wright, Katharine M.; Sur, Surojit; Gabelli, Sandra B.; Li, Yana; Ghiaur, Gabriel; Pardoll, Drew M.; Papadopoulos, Nickolas; Bettegowda, Chetan; Kinzler, Kenneth W.; Zhou, Shibin; Vogelstein, Bert
Bispecific antibodies targeting mutant RAS neoantigens
SCIENCE IMMUNOLOGY
IF16.3
2021-03-04122
OAAI
Douglass, Jacqueline; Hsiue, Emily Han-Chung; Mog, Brian J.; Hwang, Michael S.; DiNapoli, Sarah R.; Pearlman, Alexander H.; Miller, Michelle S.; Wright, Katharine M.; Azurmendi, P. Aitana; Wang, Qing; Paul, Suman; Schaefer, Annika; Skora, Andrew D.; Dal Molin, Marco; Konig, Maximilian F.; Liu, Qiang; Watson, Evangeline; Li, Yana; Murphy, Michael B.; Pardoll, Drew M.; Bettegowda, Chetan; Papadopoulos, Nickolas; Gabelli, Sandra B.; Kinzler, Kenneth W.; Vogelstein, Bert; Zhou, Shibin

研究方向

暂未获取到该数据
S
Sandra B. Gabelli
H 指数:40论文数:234被引数:7,767
S
Suman Paul
H 指数:20论文数:100被引数:2,024
C
Chetan Bettegowda
H 指数:69论文数:751被引数:3.1万
K
Kenneth W. Kinzler
H 指数:213论文数:786被引数:24.8万
S
Shibin Zhou
H 指数:49论文数:158被引数:4.0万
N
Nickolas Papadopoulos
H 指数:101论文数:530被引数:9.1万
B
Bert Vogelstein
H 指数:255论文数:1,043被引数:36.8万
S
Sarah R. DiNapoli
H 指数:18论文数:34被引数:1,450
B
Brian J. Mog
H 指数:13论文数:68被引数:1,634
E
Emily Han-Chung Hsiue
H 指数:19论文数:83被引数:1,924